Myxofibrosarcoma

• CLINICAL_TRIALS research · 2026-04-23
  Clinical Trial Update: A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg [Phase 2]

  Phase 2 trial evaluating pembrolizumab plus local chemotherapy delivered by isolated limb infusion for patients with sarcoma in the arm or l…

• CLINICAL_TRIALS research · 2026-04-21
  Clinical Trial Update: NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) [Phase 1, Phase 2]

  This is a clinical trial protocol update for NRSTS2021, a Phase 1/2 study evaluating maintenance pazopanib, limited-margin radiation therapy…

• CLINICAL_TRIALS trial_result · 2026-04-13
  Clinical Trial Update: Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma [Phase 1]

  Phase 1 trial evaluating the safety of low-dose pegylated liposomal doxorubicin in combination with peposertib for advanced sarcoma; current…

• CLINICAL_TRIALS research · 2026-03-10
  Clinical Trial Update: Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma [Phase 1]

  Phase 1 trial evaluating nivolumab plus BO-112 as a neoadjuvant treatment before surgery for resectable soft tissue sarcoma, including multi…

• CLINICAL_TRIALS research · 2026-01-28
  Clinical Trial Update: Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. [Phase 2]

  Clinical trial evaluating dose-escalated, hypofractionated definitive proton radiotherapy for patients with inoperable soft tissue sarcoma (…

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• CLINICAL_TRIALS research · 2026-01-28
  Clinical Trial Update: Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma [Phase 2]

  Phase 2 clinical trial update evaluating hypofractionated, 3-week preoperative radiotherapy using proton or photon therapy for localized sof…

• CLINICAL_TRIALS trial_result · 2025-09-23
  Clinical Trial Update: CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma [Phase 1, Phase 2]

  Clinical trial update indicates the Phase 1/Phase 2 safety and efficacy study of CAB-AXL-ADC in adult and adolescent patients with Undiffere…

• CLINICAL_TRIALS research · 2025-09-05
  Clinical Trial Update: A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors [Phase 1]

  Phase 1 first-in-human trial evaluating OKN4395 in combination with pembrolizumab in patients with solid tumors is currently recruiting. The…

• CLINICAL_TRIALS trial_result · 2025-08-28
  Clinical Trial Update: Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas [Phase 1]

  Phase 1 study of DCC-3014 in combination with Avelumab in patients with advanced or metastatic sarcoma has completed; no efficacy data is pr…

• CLINICAL_TRIALS withdrawal · 2024-07-17
  Clinical Trial Update: Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue Sarcoma [Phase 3]

  A Phase 3 trial (Brightline-3) testing brigimadlin in combination with ezabenlimab for advanced soft tissue sarcoma, including undifferentia…

• CLINICAL_TRIALS research · 2024-05-17
  Clinical Trial Update: ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma [Phase 2]

  This is a Phase 2 clinical trial update for envafolimab, administered alone or with ipilimumab, in patients with undifferentiated pleomorphi…

• CLINICAL_TRIALS trial_result · 2023-11-07
  Clinical Trial Update: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]

  Phase 2 trial evaluating doxorubicin with upfront dexrazoxane for advanced or metastatic soft tissue sarcoma has completed enrollment with r…

• CLINICAL_TRIALS trial_result · 2016-12-28
  Clinical Trial Update: Alisertib in Treating Patients With Advanced or Metastatic Sarcoma [Phase 2]

  A Phase 2 trial update of alisertib in patients with advanced or metastatic soft tissue sarcomas, including myxofibrosarcoma and several his…