Myotonic Dystrophy Type
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Technology Assisted Rehabilitation for Upper Limb Function in Myotonic Dystrophy Type 1 [NA]
A completed clinical trial evaluating technology-assisted rehabilitation for improving upper limb function in people with Myotonic Dystrophy…
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CLINICAL_TRIALS withdrawal · 2024-05-06Clinical Trial Update: Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2 [Phase 3]
A Phase 3 clinical trial evaluating mexiletine for myotonic dystrophy type 1 and type 2 has been withdrawn.
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Home-based Training and Supplementation in DM1 Patients [Phase 3]
A Phase 3 clinical trial evaluating home-based training and supplementation in patients with Myotonic Dystrophy Type 1 is ongoing (status un…
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CLINICAL_TRIALS trial_result · 2022-12-06Clinical Trial Update: A Safety andTolerability Study of Multiple Doses of ISIS-DMPKRx in Adults With Myotonic Dystrophy Type 1 [Phase 1, Phase 2]
A completed Phase 1/2 study evaluating safety and tolerability of multiple doses of ISIS-DMPKRx in adults with myotonic dystrophy type 1.
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CLINICAL_TRIALS trial_result · 2022-01-06Clinical Trial Update: Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1 [Phase 2]
Phase 2 trial assessing safety and efficacy of rhIGF-I/rhIGFBP-3 in Myotonic Dystrophy Type 1 has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-23Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of ERX-963 in Adults With Myotonic Dystrophy Type 1 [Phase 1]
Phase 1 study assessing safety, tolerability, and pharmacokinetics of ERX-963 in adults with myotonic dystrophy type 1 has been completed wi…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Brain Involvement in Myotonic Dystrophy Type I: From Functional Neuroimaging to the Impact on Quality of Life
This study investigated brain involvement in Myotonic Dystrophy Type 1 using functional neuroimaging to assess its impact on quality of life…
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CLINICAL_TRIALS trial_result · 2018-07-11Clinical Trial Update: Ventilatory Response After Non Invasive Ventilation in Type 1 Myotonic Dystrophy [NA]
This clinical trial update reports on ventilatory response after non-invasive ventilation in patients with Myotonic Dystrophy Type 1 (Steine…
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CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1 [Phase 2]
This document summarizes a Phase 2 clinical efficacy trial of mexiletine for myotonic dystrophy type 1. Results were posted in 2018.
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CLINICAL_TRIALS research · 2017-10-26Clinical Trial Update: Multicenter Observational Study of Myotonic Dystrophy Type 1
A multicenter observational study of Myotonic Dystrophy Type 1 sponsored by the University of Rochester has completed. The update notes the …
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CLINICAL_TRIALS research · 2017-07-18Clinical Trial Update: Observational Prolonged Trial in Myotonic Dystrophy Type 1 [NA]
An observational prolonged clinical trial in Myotonic Dystrophy Type 1 sponsored by Radboud University Medical Center has completed.
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Venous Thromboembolism in DM1
This clinical trial update reports the completed status of a study evaluating venous thromboembolism in myotonic dystrophy type 1.
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Compare Train and 3D-4D Left Ventricular Systolic Function in Subjects Suffering From Dystrophy and Healthy Subjects [NA]
This entry notes a terminated clinical trial comparing train and 3D-4D left ventricular systolic function in subjects with Steinert's diseas…
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CLINICAL_TRIALS research · 2016-04-06Clinical Trial Update: Tracking the Brain in Myotonic Dystrophies: a 5-year Longitudinal Follow-up Study
A 5-year longitudinal follow-up study tracking brain changes in adults with Myotonic Dystrophy Type 1 and Type 2; the study is completed.
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CLINICAL_TRIALS research · 2014-10-21Clinical Trial Update: Children's Health Research Institute(CHRI), Stanford Lucile Packard Children Hospital (LPCH) Protocol on Myotonic Dystrophy
A protocol for a clinical study on Myotonic Dystrophy Type 1 being conducted by Stanford University; the current trial status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2014-09-26Clinical Trial Update: Induction of Pluripotent Stem Cells From Human Fibroblasts of DM1 Patients [NA]
A completed clinical trial (NCT02084407) investigating induction of pluripotent stem cells from human fibroblasts of patients with myotonic …
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CLINICAL_TRIALS trial_result · 2012-02-20Clinical Trial Update: DM1 Heart Registry - DM1 Respiratory Registry
This document reports a completed status update for the DM1 Heart Registry and DM1 Respiratory Registry sponsored by Institut de Myologie (F…
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CLINICAL_TRIALS trial_result · 2011-08-23Clinical Trial Update: Methylphenidate in Myotonic Dystrophy Type 1 [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating methylphenidate for myotonic dystrophy type 1 has completed, with Laval University listed as sponsor. …
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CLINICAL_TRIALS trial_result · 2010-02-01Clinical Trial Update: Effects of SomatoKine (Iplex)Recombinant Human Insulin-like Growth Factor-1/Recombinant Human Insulin-like Growth Factor-binding Protein-3 (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1) [Phase 1, Phase 2]
Phase 1/2 study of SomatoKine (Iplex), a recombinant IGF-1 and IGFBP-3 combination, in Myotonic Dystrophy Type 1 has completed and results a…