Myeloproliferative Neoplasm
📧 Sign up to get email alerts when something new happens for Myeloproliferative Neoplasm.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome [Phase 3]
Phase 3 trial evaluating response-based chemotherapy in younger patients with Down syndrome who have newly diagnosed acute myeloid leukemia …
-
CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update describing the addition of itacitinib to cyclophosphamide and tacrolimus for preventing graft-versus-host dise…
-
CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study
This completed clinical trial (NCT05053100) investigates the risk of blood clots and bleeding in patients with hematologic cancers.
-
CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Determination of the Clonality Profile in Myeloproliferative Neoplasms and Association With the Thrombotic Complications (CLOJAK)
This ClinicalTrials.gov entry describes the CLOJAK study, a recruiting trial evaluating clonality profiles in myeloproliferative neoplasms a…
-
CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Study of IMGN632 in Patients With Untreated BPDCN and Relapsed/Refractory BPDCN [Phase 1, Phase 2]
An ongoing Phase 1/2 trial of IMGN632 for untreated and relapsed/refractory Blastic plasmacytoid dendritic cell neoplasm. The study is curre…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS withdrawal · 2024-12-05Clinical Trial Update: Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT [Phase 1]
A Phase 1 trial evaluating a preemptive infusion of donor lymphocytes depleted of TCR+ T cells and CD19+ B cells after autologous stem cell …
-
CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Evaluation of CPX-351 Monotherapy in Acute Myeloid Leukemia Secondary to Myeloproliferative Neoplasm [Phase 2]
Phase 2 evaluation of CPX-351 monotherapy in acute myeloid leukemia secondary to myeloproliferative neoplasm has completed.
-
CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms [Phase 1]
The Phase 1 study of TAS1553 in subjects with relapsed or refractory acute myeloid leukemia and other myeloid neoplasms has been terminated.
-
CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
-
CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: Exploring the Impact of Monocytes in Myeloproliferative Neoplasia (EMYNEM)
A recruiting clinical trial investigating the role of monocytes in myeloproliferative neoplasms. The study is sponsored by University Hospit…
-
CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
-
CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: 2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II [Phase 1, Phase 2]
This Phase I/II clinical trial evaluated Interleukin-7 for T-cell recovery after haploidentical and cord blood stem cell transplantation and…
-
CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating high-dose cyclophosphamide, tacrolimus, and mycophenolate mofetil to prevent graft-versus-host disease in …
-
CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease [Phase 2]
Phase 2 clinical trial investigating salsalate, venetoclax, and decitabine or azacitidine for acute myeloid leukemia and advanced myelodyspl…
-
CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Phase 3]
Phase 3 trial comparing Tacrolimus plus mini-methotrexate versus Tacrolimus plus methotrexate for graft-versus-host disease prevention has c…
-
CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
Phase 2 trial evaluating decidual stromal cells for treatment of steroid-refractory graft-versus-host disease after allogeneic stem cell tra…
-
CLINICAL_TRIALS trial_result · 2022-06-22Clinical Trial Update: Remotely Administered Diet Intervention to Impact Symptom Burden in Myeloproliferative Neoplasm [Phase 2]
Phase 2 clinical trial evaluating a remotely administered diet intervention to reduce symptom burden in patients with myeloproliferative neo…
-
CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid [Phase 2]
Phase 2 trial updating TET2 mutation targeting with azacitidine plus ascorbic acid in myelodysplastic syndromes and acute myeloid leukemia h…
-
CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma [Phase 2]
Phase 2 trial evaluating CD8+ memory T-cells as consolidative therapy after donor non-myeloablative hematopoietic cell transplant in leukemi…
-
CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms [Phase 1, Phase 2]
Phase 1b/2 trial assessing APR-246 plus azacitidine in TP53-mutant myeloid neoplasms completed with posted results.
-
CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation [Phase 2]
Phase 2 clinical trial update evaluating a sympathicomimetic agonist in patients with myeloproliferative neoplasms carrying JAK2 mutations, …
-
CLINICAL_TRIALS trial_result · 2019-05-01Clinical Trial Update: Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies [Phase 2]
Phase 2 clinical trial evaluating BL-8040 for mobilizing donor hematopoietic stem cells to enable allogeneic transplantation in patients wit…
-
CLINICAL_TRIALS trial_result · 2018-10-05Clinical Trial Update: Pacritinib Before Transplant for Myeloproliferative Neoplasms (MPN) [Phase 2]
Phase 2 trial of pacritinib before transplantation in myeloproliferative neoplasms was terminated with results posted in 2018.
-
CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm [NA]
This clinical trial update reports results for using decitabine plus cytarabine in older adults with untreated acute myeloid leukemia, high-…