Myeloid Malignancies
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Germline Testing for Predisposition to Myeloid Malignancies [NA]
Ongoing recruitment for a germline genetic testing study aimed at identifying predisposition to myeloid malignancies.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Telehealth Advance Care Planning Intervention [NA]
An ongoing clinical trial at the University of Rochester is evaluating a telehealth advance care planning intervention for myeloid malignanc…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Considering alloHCT: Opportunities for Patient Reflection During Decision-Making Via Digital Stories [NA]
A clinical trial update exploring how digital stories can help patients reflect on choosing allogeneic hematopoietic cell transplantation fo…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: US Study of ECT-001-CB in Pediatric and Young Adult Patients With High-Risk Myeloid Malignancies [Phase 1, Phase 2]
ExCellThera's US trial of ECT-001-CB in pediatric and young adult patients with high-risk myeloid malignancies (cord blood transplant) has c…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Reduced MBF Regimen for Patients >=55 Years With Myeloid Malignancies [Phase 2]
A Phase 2 clinical trial evaluating a reduced MBF regimen for patients 55 years and older with myeloid malignancies, currently recruiting an…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid Malignancies [Phase 1, Phase 2]
This clinical trial update describes an ongoing Phase 1/2 study of CAR.70-engineered IL15-transduced cord blood-derived NK cells with TGFBR2…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Phase II Open-label Study of Olutasidenib Post-transplant Maintenance Therapy for Patients With IDH1-mutated Myeloid Malignancies [Phase 2]
Phase II open-label study evaluating olutasidenib as post-transplant maintenance therapy for patients with IDH1-mutated myeloid malignancies…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies [Phase 1]
A Phase 1 clinical trial update for a study of novel anti-leukemia agents used in Flu/Mel reduced-intensity conditioning transplant for myel…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies [Phase 1]
A Phase 1 trial evaluating CC-486/Onureg in participants with hepatic impairment versus normal hepatic function in myeloid malignancies has …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies. [Phase 2]
Phase 2 pediatric trial evaluating GVHD prophylaxis without calcineurin inhibitors after day 60 post first allogeneic hematopoietic stem cel…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML [Phase 1, Phase 2]
This clinical trial update reports that Lisaftoclax (APG-2575) is being studied as a single agent and in combination for relapsed/refractory…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: A Study of GLB-001 in Patients With Myeloid Malignancies [Phase 1]
A Phase 1 clinical trial evaluating GLB-001 in patients with myeloid malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: VEN+DAC+Bu2Flu4 vs Bu2Flu5 Conditioning Regimen for Elderly Myeloid Malignancies Undergoing Allo-HSCT [Phase 2, Phase 3]
A Phase 2/Phase 3 trial update evaluating venetoclax plus decitabine with a Busulfan/Fludarabine conditioning regimen (Bu2Flu4) versus Bu2Fl…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML [Phase 1]
Phase 1 clinical trial update for GTB-3650 Trike in high-risk myeloid malignancies, including acute myeloid leukemia and myelodysplastic syn…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Exploratory Clinical Study on the Safety and Efficacy of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Myeloid Malignancies [Phase 1, Phase 2]
An exploratory Phase 1/2 clinical study evaluating the safety and efficacy of CAR-T cell therapy for relapsed/refractory myeloid malignancie…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Study of Magrolimab Combinations in Participants With Myeloid Malignancies [Phase 2]
Phase 2 study evaluating magrolimab combinations in participants with myeloid malignancies was terminated; results have been posted.
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CLINICAL_TRIALS withdrawal · 2024-11-22Clinical Trial Update: MyeloGen: Germline Testing for Predisposition to Myeloid Malignancies [NA]
The clinical trial MyeloGen investigating germline testing for predisposition to myeloid malignancies has been withdrawn. No further details…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Hypomethylating Agent and Venetoclax After Allo-HSCT in Patients With High-risk Myeloid Malignancies. [Phase 2]
Phase 2 clinical trial evaluating a hypomethylating agent in combination with venetoclax after allogeneic stem cell transplantation in high-…
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: Ph2 NK Cell Enriched DCIs w/wo RLR9 Agonist, DUK-CPG-001 From Donors Following Allogeneic SCT [Phase 2]
Phase 2 trial update on natural killer (NK) cell-enriched dendritic cell vaccines with or without a RLR9 agonist (DUK-CPG-001) from donors a…
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: Fractionated Busulfan Conditioning Regimen for Allo-HSCT in Non-remission Myeloid Malignancies [Phase 2]
Phase 2 trial update on fractionated busulfan conditioning before allogeneic stem cell transplantation in myeloid malignancies.
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies [Phase 2]
Phase 2 clinical trial update assessing post-transplant high-dose cyclosporine as GvHD prophylaxis in 1 HLA-mismatched unrelated hematopoiet…
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CLINICAL_TRIALS trial_result · 2021-09-21Clinical Trial Update: Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis [Phase 2]
Phase 2 trial of imetelstat sodium in adults with primary or secondary myelofibrosis has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2019-10-10Clinical Trial Update: Decitabine + BUCY vs BUCY Conditioning Regimen for TP53+ Myeloid Tumors Undergoing Allo-HSCT [Phase 2, Phase 3]
Phase 2/3 trial evaluating decitabine in combination with a BUCY conditioning regimen versus BUCY alone for TP53+ myeloid tumors undergoing …
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CLINICAL_TRIALS trial_result · 2019-06-25Clinical Trial Update: A Clinical Research of CD33-Targeted CAR-T in Myeloid Malignancies [Phase 1, Phase 2]
Clinical trial update for a CD33-targeted CAR-T therapy in myeloid malignancies (Phase 1/Phase 2) with unknown status.
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: A Clinical Research of LeY-Targeted CAR-T in Myeloid Malignancies [Phase 1, Phase 2]
Clinical trial update for LeY-targeted CAR-T in myeloid malignancies currently in Phase 1/Phase 2.