Myelofibrosis
📧 Sign up to get email alerts when something new happens for Myelofibrosis.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid Malignancies [Phase 1, Phase 2]
This document provides an update on the completed Phase 1/2 trial of SB1518 for advanced myeloid malignancies.
-
CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: A Phase 1/2 Study of Oral SB1518 in Subjects With Chronic Idiopathic Myelofibrosis [Phase 1, Phase 2]
The Phase 1/2 study of oral SB1518 (pacritinib) in chronic idiopathic myelofibrosis has completed, with the trial listing other myeloprolife…
-
CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: Low-Dose Decitabine in Treating Patients With Symptomatic Myelofibrosis [Phase 2]
Phase 2 trial evaluating low-dose decitabine for symptomatic myelofibrosis was terminated, with results posted in 2012.
-
CLINICAL_TRIALS trial_result · 2012-01-24Clinical Trial Update: COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial [Phase 3]
Phase 3 COMFORT-I trial evaluating the oral JAK inhibitor ruxolitinib for myelofibrosis completed, with results posted.
-
CLINICAL_TRIALS trial_result · 2012-01-20Clinical Trial Update: PTK 787 and Gleevec in Patients With AML, AMM, and CML-BP [Phase 1, Phase 2]
This clinical trial update reports Phase 1/Phase 2 results for the combination of PTK 787 and imatinib (Gleevec) in patients with acute myel…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2012-01-13Clinical Trial Update: Imatinib Mesylate in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 trial evaluating imatinib mesylate in patients with primary myelofibrosis. The study was terminated and results were posted in Janua…
-
FDA approval · 2011-11-16FDA Approved: JAKAFI — Original Application (Incyte Corporation)
The FDA granted original approval for JAKAFI (ruxolitinib) by Incyte Corporation, marking the first approval of this drug for the treatment …
-
CLINICAL_TRIALS trial_result · 2011-05-04Clinical Trial Update: CEP-701 for PH-negative Myelofibrosis [Phase 2]
Phase 2 clinical trial of CEP-701 (lestaurtinib) for PH-negative myelofibrosis completed, with results posted in May 2011.
-
CLINICAL_TRIALS trial_result · 2011-05-02Clinical Trial Update: Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload [Phase 3]
This Phase 3 expanded-access update describes deferasirox use for patients with congenital disorders of red blood cells and chronic iron ove…
-
CLINICAL_TRIALS withdrawal · 2011-04-28Clinical Trial Update: Creation of Bone Marrow Microenvironment for Treatment of Myelodysplastic Syndrome (MDS) in Conjunction With Allogeneic Stem Cell Transplantation [Phase 2]
The Phase 2 trial investigating the creation of a bone marrow microenvironment to treat myelodysplastic syndromes in conjunction with alloge…
-
CLINICAL_TRIALS trial_result · 2011-04-08Clinical Trial Update: Assessment of Labile Plasma Iron (LPI) in Myelodysplastic Syndromes (MDS) and Primary Myelofibrosis
This clinical trial update assesses labile plasma iron (LPI) in patients with myelodysplastic syndromes and primary myelofibrosis; the curre…
-
CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: A Safety Study of XL019 in Adults With Myelofibrosis [Phase 1]
This clinical trial update reports termination of a Phase 1 safety study of XL019 in adults with myelofibrosis and related myeloproliferativ…
-
CLINICAL_TRIALS trial_result · 2011-03-30Clinical Trial Update: Ph II Study of Azacitidine in Myelofibrosis [Phase 2]
A Phase II study of azacitidine in myelofibrosis has completed and results were posted in 2011.
-
CLINICAL_TRIALS trial_result · 2011-03-17Clinical Trial Update: Thalidomide, Prednisone, and Cyclophosphamide in Treating Patients With Myelofibrosis and Myeloid Metaplasia [Phase 2]
Phase 2 trial evaluating thalidomide, prednisone, and cyclophosphamide in patients with myelofibrosis and myeloid metaplasia; the study has …
-
CLINICAL_TRIALS trial_result · 2011-02-21Clinical Trial Update: A Phase II Study of CC-5013 in Myelofibrosis [Phase 2]
Phase II study of CC-5013 in myelofibrosis has completed and posted results.
-
CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Azacitidine in Treating Patients With Myelofibrosis [Phase 2]
A Phase 2 trial of azacitidine in patients with myelofibrosis was terminated; results were posted in January 2011.
-
CLINICAL_TRIALS trial_result · 2010-06-17Clinical Trial Update: Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating chemotherapy followed by peripheral stem cell transplantation in patients with myelofibrosis; the study ha…
-
CLINICAL_TRIALS trial_result · 2009-10-26Clinical Trial Update: A Dose-escalation Study of the Safety and Tolerability of Orally Administered TG101348 in Patients With Myelofibrosis [Phase 1]
This Phase 1 dose-escalation study reports on the safety and tolerability of orally administered TG101348 in patients with myelofibrosis.
-
CLINICAL_TRIALS research · 2009-10-12Clinical Trial Update: Bone Marrow Transplant Chart Review for RIC
Completed chart-review study evaluating reduced-intensity conditioning bone marrow transplant for myelofibrosis.
-
CLINICAL_TRIALS trial_result · 2009-05-05Clinical Trial Update: A Phase 1 Study of MKC-1 in Patients With Refractory Hematologic Malignancies [Phase 1]
This document reports a Phase 1 trial of MKC-1 in patients with refractory hematologic malignancies, including myelodysplastic syndromes and…