Myelofibrosis
📧 Sign up to get email alerts when something new happens for Myelofibrosis.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases [Phase 2]
Phase 2 trial evaluating myeloablative umbilical cord blood transplantation in various hematological diseases has completed with results pos…
-
CLINICAL_TRIALS trial_result · 2020-08-14Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Idelalisib in Adults Receiving Ruxolitinib as Therapy for Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis With Progressive or Relapsed Disease [Phase 1]
Phase 1 trial evaluating safety, tolerability, and pharmacokinetics of idelalisib in adults with myelofibrosis receiving ruxolitinib; study …
-
CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia [Phase 2]
Phase 2 single-arm trial evaluating oral rigosertib in myelofibrosis with anemia was terminated; results posted.
-
CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: Efficacy and Safety of Simtuzumab in Adults With Primary, Post Polycythemia Vera or Post Essential Thrombocythemia Myelofibrosis [Phase 2]
Phase 2 trial assessing the efficacy and safety of simtuzumab in adults with primary myelofibrosis or post polycythemia vera/post essential …
-
CLINICAL_TRIALS trial_result · 2020-06-02Clinical Trial Update: AZD1775 in Advanced Acute Myeloid Leukemia, Myelodysplastic Syndrome and Myelofibrosis [Phase 2]
Phase 2 trial of AZD1775 in advanced acute myeloid leukemia, myelodysplastic syndromes, and myelofibrosis was terminated with posted results…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2020-05-27Clinical Trial Update: Allogeneic Stem Cell Transplantation for Multiple Myeloma and Myelofibrosis [Phase 2]
Phase 2 trial update on allogeneic stem cell transplantation for multiple myeloma and myelofibrosis; the study status is terminated with pos…
-
CLINICAL_TRIALS trial_result · 2020-04-30Clinical Trial Update: Efficacy and Safety of Ruxolitinib in the Treatment of Anemic Myelofibrosis Patients. [Phase 2]
Phase 2 trial update on the efficacy and safety of ruxolitinib in treating anemic myelofibrosis, with completed status and results posted.
-
CLINICAL_TRIALS trial_result · 2020-04-15Clinical Trial Update: A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF [Phase 1, Phase 2]
Phase Ib/II dose-finding study assessing safety and efficacy of LDE225 plus INC424 in myelofibrosis patients completed with posted results.
-
CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF) [Phase 2]
Phase 2 trial assessing ruxolitinib (INCB018424) in participants with primary myelofibrosis and related post-MPN myelofibrosis conditions ha…
-
CLINICAL_TRIALS trial_result · 2020-01-21Clinical Trial Update: Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT [Phase 1]
Phase 1 trial exploring a calcineurin inhibitor-free graft-versus-host disease prevention regimen after related haploidentical peripheral bl…
-
FDA approval · 2020-01-14FDA Approved: JAKAFI — Supplemental Application (Incyte Corporation)
FDA approved a supplemental application for JAKAFI (ruxolitinib) submitted by Incyte Corporation, resulting in a label change and/or expande…
-
CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Phase IIA Study of the HDAC Inhibitor ITF2357 in Patients With JAK-2 V617F Positive Chronic Myeloproliferative Diseases [Phase 2]
Phase IIa study of HDAC inhibitor ITF2357 in JAK-2 V617F positive myeloproliferative diseases has completed with posted results.
-
CLINICAL_TRIALS trial_result · 2019-10-21Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]
Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…
-
CLINICAL_TRIALS trial_result · 2019-09-03Clinical Trial Update: Asian Phase II Study of INC424 in Patients With Primary Myelofibrosis (MF), Post-PV MF or Post-ET MF [Phase 2]
Phase II clinical trial update for INC424 (sonidegib) in various myelofibrosis subtypes has completed with posted results.
-
FDA approval · 2019-08-16FDA Approved: INREBIC — Original Application (Celgene Corporation)
FDA approved INREBIC (fedratinib hydrochloride) from Celgene as an original application for adults with myelofibrosis.
-
CLINICAL_TRIALS trial_result · 2019-08-16Clinical Trial Update: Phase III Study Investigating the Efficacy and Safety of Ruxolitinib in Early Myelofibrosis Patients With High Molecular Risk Mutations. [Phase 3]
Phase III study of ruxolitinib in early myelofibrosis with high molecular risk mutations was terminated; results posted in 2019.
-
CLINICAL_TRIALS trial_result · 2019-07-31Clinical Trial Update: Ruxolitinib and Lenalidomide for Patients With Myelofibrosis [Phase 2]
Phase 2 trial evaluating the combination of ruxolitinib and lenalidomide in patients with myelofibrosis; results were posted in 2019 after s…
-
CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Lenalidomide for Patients With Myelofibrosis (MF) [Phase 2]
Phase 2 clinical trial update evaluating lenalidomide in patients with myelofibrosis.
-
CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Ruxolitinib and Pracinostat Combination Therapy for Patients With Myelofibrosis (MF) [Phase 2]
Phase 2 clinical trial evaluating ruxolitinib in combination with pracinostat for myelofibrosis has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Nivolumab in Treating Patients With Primary Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis, or Post-Polycythemia Vera Myelofibrosis [Phase 2]
Phase 2 trial evaluating nivolumab in various myelofibrosis-related conditions, terminated with posted results.
-
CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation [Phase 2]
Phase 2 clinical trial update evaluating a sympathicomimetic agonist in patients with myeloproliferative neoplasms carrying JAK2 mutations, …
-
CLINICAL_TRIALS trial_result · 2019-05-06Clinical Trial Update: Dasatinib as Therapy for Myeloproliferative Disorders (MPDs) [Phase 2]
Phase 2 trial evaluating dasatinib for myeloproliferative disorders; the study has completed and results were posted in 2019.
-
CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: INC424 for Patients With Primary Myelofibrosis, Post Polycythemia Myelofibrosis or Post-essential Thrombocythemia Myelofibrosis. [Phase 3]
Phase 3 trial update for INC424 in patients with myelofibrosis including primary, post-polycythemia myelofibrosis, or post-essential thrombo…
-
CLINICAL_TRIALS trial_result · 2019-04-04Clinical Trial Update: PTCy and Ruxolitinib GVHD Prophylaxis in Myelofibrosis [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated prophylaxis for graft-versus-host disease using post-transplant cyclophosphamide and ruxolitinib in pat…
-
CLINICAL_TRIALS trial_result · 2019-03-20Clinical Trial Update: Ruxolitinib Prior to Transplant in Patients With Myelofibrosis [Phase 2]
Phase 2 trial evaluating ruxolitinib before transplant in myelofibrosis was terminated; results posted in 2019.