Myelofibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of TQ05105 Tablets in Subjects With Intermediate/High-risk Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating the efficacy, safety, and pharmacokinetics of TQ05105 tablets in intermediate/high-risk myelofibrosis is n…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Feasibility Trial of Extracorporeal Iron Purification in Patients With Myelodysplastic Syndrome or Myelofibrosis [NA]
A feasibility clinical trial evaluating extracorporeal iron purification as a treatment approach for patients with myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Therapeutic RSK1 Targeting in Myelofibrosis [Phase 1]
A Phase 1 clinical trial update focusing on a therapy targeting RSK1 for myelofibrosis, which is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis [Phase 2]
This update describes a Phase 2 study evaluating momelotinib in combination with luspatercept for transfusion-dependent myelofibrosis; the t…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT [Phase 1]
Stanford is conducting a Phase 1 study evaluating cessation of tacrolimus immunosuppression after allogeneic hematopoietic cell transplantat…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF) [Phase 3]
This Phase 3 trial evaluates pelabresib in combination with ruxolitinib for myelofibrosis and is currently recruiting across primary MF and …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms [Phase 1]
This clinical trial update announces a Phase 1 study of JNJ-88549968 for CALR-mutated myeloproliferative neoplasms and indicates the trial i…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study of ZE74-0282 for Patients With JAK2 V617F Positive Blood Cancers [Phase 1]
ZE74-0282 is the subject of a Phase 1 trial for JAK2 V617F-positive blood cancers, including polycythemia vera and myelofibrosis, and the st…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial is evaluating oral Nuvisertib (TP-3654) in patients with myelofibrosis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy [Phase 1]
Phase 1 clinical trial sponsored by the University of Alabama at Birmingham evaluating UAB 2419-CD34 selection using the CliniMACS Prodigy s…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs) [Phase 2]
A Phase 2 randomized trial evaluating ASTX727 with or without iadademstat in advanced myeloproliferative neoplasms, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis [Phase 3]
A Phase 3 clinical trial update evaluating the combination of selinexor and ruxolitinib for myelofibrosis; the study is currently active but…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts [Phase 4]
This clinical trial update describes a Phase 4 study comparing momelotinib to ruxolitinib in adults with untreated myelofibrosis and low blo…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: ENERGIA: Personalized Exercise Program for Fatigue in Patients With Myeloproliferative Neoplasms and Chronic Myeloid Leukemia [NA]
The ENERGIA study tests a personalized exercise program to reduce fatigue in patients with myeloproliferative neoplasms and chronic myeloid …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Clinical Trial of Flonoltinib Maleate Tablets in the Treatment of JAK Inhibitor Refractory/Relapsed/Intolerant Patients With Medium to High Risk Myelofibrosis [Phase 2]
This is a Phase 2 clinical trial evaluating Flonoltinib Maleate Tablets in patients with medium to high-risk myelofibrosis who are refractor…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Hepatic Impairment Subjects [Phase 1]
This Phase 1 study evaluates the pharmacokinetics and safety of TQ05105 Tablet in hepatic impairment subjects with myelofibrosis, and the tr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Telehealth Advance Care Planning Intervention [NA]
An ongoing clinical trial at the University of Rochester is evaluating a telehealth advance care planning intervention for myeloid malignanc…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis [Phase 1, Phase 2]
Recruiting for a phase 1/2 study combining ruxolitinib with ulixertinib in patients with myelofibrosis.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017) [Phase 3]
Phase 3 study of bomedemstat (MK-3543-017) sponsored by Merck is currently recruiting to evaluate safety and efficacy in essential thrombocy…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis [Phase 1]
Phase 1 study evaluating pelabresib added to ruxolitinib in Japanese adults with myelofibrosis (primary, post-polycythemia vera, or post-ess…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Momelotinib During and After HCT in Myelofibrosis [Phase 1]
A Phase 1 clinical trial evaluating momelotinib during and after hematopoietic cell transplantation in patients with myelofibrosis is curren…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms [Phase 1]
Phase 1 study of PRT12396 in select myeloproliferative neoplasms is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Registry Platform Myelofibrosis and Anemia
A ClinicalTrials.gov registry entry for a recruiting trial by iOMEDICO AG focused on myelofibrosis and anemia. It lists several MF-related c…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers [Phase 1]
Phase 1 trial update for IOA-244, a PI3Kδ inhibitor, being studied in metastatic cancers with status currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Evaluate Safety , Efficacy and Pharmacokinetics of WJ01024 Tablets Combined With Ruxolitinib in Patients With Myelofibrosis [Phase 1, Phase 2]
A phase 1/2 clinical trial update evaluating safety, efficacy, and pharmacokinetics of WJ01024 tablets in combination with ruxolitinib for i…