Myelodysplastic Syndromes
📧 Sign up to get email alerts when something new happens for Myelodysplastic Syndromes.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Removing Transfusion Dependence as a Barrier to Hospice Enrollment [NA]
A completed clinical trial update indicates that transfusion dependence was removed as a barrier to hospice enrollment for patients with hem…
-
CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS) [Phase 1]
A Phase 1 study evaluating an oral tetrahydrouridine-decitabine combination for relapsed or refractory myelodysplastic syndromes is currentl…
-
CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes [Phase 2]
This is a Phase 2 study evaluating intensity-modulated total marrow irradiation added to fludarabine/busulfan conditioning for allogeneic tr…
-
CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1]
MacroGenics reports a Phase 1 study of MGD024 in relapsed or refractory hematologic malignancies is currently recruiting across multiple dis…
-
CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating the combination of venetoclax and azacitidine for relapsed or refrac…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS [Phase 1]
Phase 1 clinical trial evaluating Venetoclax in combination with intensive chemotherapy for acute myeloid leukemia and advanced myelodysplas…
-
CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab. [Phase 2]
A Phase 2 rollover study from Novartis continues Sabatolimab (MBG453) treatment for patients who completed a prior study, to assess continue…
-
CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Study of TAK-226 for Transfusion-Dependent Anemia in Japanese Patients With Lower-Risk Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial evaluating TAK-226 for transfusion-dependent anemia in Japanese patients with lower-risk myelodysplastic syndromes …
-
CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT [NA]
This clinical trial (NCT07319793) sponsored by Peking University People's Hospital is evaluating pre-DLI or pro-DLI approaches in relapsed o…
-
CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) [NA]
A completed clinical trial update reporting long-term outcomes of alternative donor allogeneic transplantation across multiple hematologic d…
-
CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT [Phase 1]
Phase 1 trial evaluating a combination of CD25/Treg-depleted donor lymphocyte infusion with ipilimumab for relapse of myeloid diseases after…
-
CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
A registry-based study (Biology and Outcome Project) enrolling patients with acute myeloid leukemia and myelodysplastic syndromes/AML to cha…
-
CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Efficiency of Antibacterial Prophylaxis in Azacitidine Treated Patients [Phase 3]
Phase 3 trial evaluating antibacterial prophylaxis in azacitidine-treated patients has completed.
-
CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation [Phase 1]
Phase 1 clinical trial evaluating preemptive CIML NK cell therapy after hematopoietic stem cell transplantation in patients with acute myelo…
-
CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts [Phase 2]
A Phase II trial is evaluating a combination regimen of cladribine and low-dose cytarabine with venetoclax, alternating with azacitidine and…
-
CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Follow-up Study of ICUS and CCUS Patients
This document provides an update on a follow-up clinical study of ICUS and CCUS patients with myelodysplastic syndromes, including enrollmen…
-
CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation [Phase 2]
A Phase 2 dose-expansion study evaluating a low-dose post-transplant cyclophosphamide/tacrolimus/ruxolitinib regimen for graft-versus-host d…
-
CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe. [Phase 1, Phase 2]
A Phase 1/2 clinical trial is testing an improved dose of UM171 to enhance the effectiveness and safety of cord blood transplantation; recru…
-
CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome [Phase 1]
A Phase 1 clinical trial update evaluating SX-682 alone and in combination with decitabine in patients with myelodysplastic syndromes. The s…
-
CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating GVHD prophylaxis with post-transplant cyclophosphamide plus sirolimus and VIC-1911 in myeloablative peripheral bl…
-
CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research Study
A clinical trial update describing a secondary research study that analyzes molecular and clinical aspects of bone marrow failure and VEXAS …
-
CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS [Phase 1]
Phase 1 study of JNJ-64619178, a PRMT5 inhibitor, in participants with advanced solid tumors, Non-Hodgkin Lymphoma, and lower-risk myelodysp…
-
EMA approval · 2025-12-18EMA Authorised: Azacitidine Kabi (azacitidine) — Fresenius Kabi Deutschland GmbH
EMA authorised Azacitidine Kabi (azacitidine) from Fresenius Kabi Deutschland GmbH for use in the EU. The product is indicated for myelodysp…
-
CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Home Blood Transfusions [NA]
Thomas Jefferson University is recruiting for a clinical trial on home blood transfusions. The study targets patients with hematologic malig…
-
CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects [Phase 1]
Phase 1 study evaluating single and multiple dose administration of LP-001 in healthy subjects has completed.