Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Pathogenesis of Hematologic Malignancies
An update on an ongoing clinical trial exploring the pathogenesis of hematologic malignancies, with enrollment by invitation at the sponsor …
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Interferon γ-Primed Mesenchymal Stromal Cells as Prophylaxis for Acute Graft v Host Disease [Phase 1]
Phase 1 trial evaluating interferon-γ-primed mesenchymal stromal cells as prophylaxis for acute graft-versus-host disease in patients with a…
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CLINICAL_TRIALS withdrawal · 2026-02-13Clinical Trial Update: Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of decitabine, cedazuridine (ASTX727), and ASTX029 (an ERK inhibitor) for patients wit…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Asia Myelodysplastic Syndrome (MDS) Registry
Asia-based registry study on myelodysplastic syndromes (MDS) sponsored by Bristol-Myers Squibb is currently NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
A Dana-Farber Cancer Institute-led clinical study recruiting to investigate molecular progression and clinical outcomes in MGUS, smoldering …
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS [Phase 1]
Phase 1 trial SENTI-202 evaluating off-the-shelf logic-gated CAR NK cells for CD33 and/or FLT3-expressing hematologic cancers including acut…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: National Longitudinal Cohort of Hematological Diseases
Recruiting for a national longitudinal cohort study of hematological diseases sponsored by the Institute of Hematology & Blood Diseases Hosp…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Quality of Life-Guided Transfusion in Refractory MDS or AML [NA]
A clinical trial evaluating quality-of-life-guided transfusion in adults with refractory myelodysplastic syndromes or acute myeloid leukemia…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation [NA]
The document updates a clinical trial evaluating an electronic health mindfulness-based music therapy intervention for patients undergoing a…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: DR-18 for the Treatment of Relapsed or Persistent Acute Myeloid Leukemia or Myelodysplastic Syndrome After Hematopoietic Cell Transplantation, the DR. DREAM Trial [Phase 1]
Phase 1 trial DR-18 for relapsed or persistent acute myeloid leukemia or myelodysplastic syndrome after hematopoietic cell transplantation i…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) [Phase 2]
A Takeda-sponsored Phase 2 trial evaluating Elritercept for treating anemia in adults with very low, low, or intermediate-risk myelodysplast…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations
A multicenter observational study assessing myocardial iron overload in three transfused populations has completed, focusing on patients wit…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis [Phase 2]
Phase 2 clinical trial evaluating reduced-dose post-transplant cyclophosphamide as GVHD prophylaxis in HLA-mismatched unrelated donor periph…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS [Phase 1]
Phase 1 study evaluating APL-4098 alone and in combination for adults with acute myeloid leukemia or myelodysplastic syndromes; currently re…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Defining Inflammatory Markers of Cardiovascular Disease in Patients With Myelodysplastic Syndromes
A clinical trial sponsored by the University of Vermont is recruiting to study inflammatory markers associated with cardiovascular disease i…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: The National Myelodysplastic Syndromes (MDS) Study
The NHLBI-sponsored National Myelodysplastic Syndromes study (NCT02775383) has completed.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis [NA]
This clinical trial is investigating anti-platelet antibodies detected with the MAIPA assay to demonstrate the autoimmune nature of thromboc…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: PK/Efficacy Bridging Study of ASTX727 in Chinese Subjects With Myelodysplastic Syndromes [Phase 1, Phase 2]
This is a Phase 1/2 PK and efficacy bridging study of ASTX727 in Chinese patients with myelodysplastic syndromes, sponsored by Otsuka Beijin…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT [Phase 1]
A Phase I clinical trial for patients with advanced hematologic malignancies undergoing allogeneic hematopoietic cell transplantation is cur…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders [Phase 2]
Phase 2 clinical trial update investigating alpha/beta T cell receptor alpha/beta-depleted hematopoietic cell transplantation in inherited b…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms [Phase 1]
Phase 1 clinical trial evaluating a triple combination of navitoclax, venetoclax, and decitabine for advanced myeloid neoplasms. The study i…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Romiplostim N01 for Platelet Recovery After Haploidentical HSCT [Phase 1]
Phase 1 clinical trial evaluating Romiplostim N01 for platelet recovery after haploidentical hematopoietic stem cell transplantation. The st…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating induction and consolidation with fludarabine, cytarabine, idarubicin, and venetoclax for acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms. [Phase 1]
A Phase 1 clinical trial of BYON4413 in relapsed/refractory acute myeloid leukemia and myelodysplastic neoplasms reports safety, pharmacokin…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: ONC-201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant [Phase 1]
Phase 1 trial of ONC-201 as maintenance therapy after stem cell transplant in acute myeloid leukemia and myelodysplastic syndromes has compl…