Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-01-13Clinical Trial Update: Prospective, Multicenter, Open Label and Single-arm Study of Darbepoetin Alfa for Anemia in Myelodisplastic Syndrome Patients. [Phase 2]
A Phase 2, multicenter, open-label, single-arm trial evaluating darbepoetin alfa for anemia in myelodysplastic syndromes has been terminated…
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CLINICAL_TRIALS trial_result · 2009-12-31Clinical Trial Update: Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers. [Phase 2]
Phase 2 clinical trial evaluating donor umbilical cord blood natural killer cells with aldesleukin and umbilical cord blood transplant in re…
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CLINICAL_TRIALS trial_result · 2009-11-25Clinical Trial Update: Peripheral Blood (PB) Versus Bone Marrow (BM) in Allogeneic Stem Cell Transplantation [Phase 3]
This Phase 3 trial comparing peripheral blood versus bone marrow as graft sources in allogeneic stem cell transplantation has completed. It …
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CLINICAL_TRIALS trial_result · 2009-11-18Clinical Trial Update: Treatment of the Anemia of Myelodysplastic Syndromes by the Association of Epoetin Beta and All Trans Retinoic Acid [Phase 2]
This document reports a Phase 2 clinical trial evaluating the combination of epoetin beta and all-trans retinoic acid for anemia in myelodys…
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CLINICAL_TRIALS trial_result · 2009-09-04Clinical Trial Update: A Study of Decitabine Given to Adults With Advanced-Stage Myelodysplastic Syndromes [Phase 2]
Phase 2 study evaluating decitabine in adults with advanced myelodysplastic syndromes has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2009-09-03Clinical Trial Update: Donor Umbilical Cord Blood Transplant By Injection Into the Bone Marrow in Treating Patients With Hematologic Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor umbilical cord blood transplant by intra-bone-marrow injection for hematologic cancers; trial term…
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CLINICAL_TRIALS research · 2009-07-08Clinical Trial Update: Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants
This clinical trial update describes biomarkers studied in people at risk for myelodysplastic syndromes and in healthy participants, sponsor…
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CLINICAL_TRIALS trial_result · 2009-05-12Clinical Trial Update: Amifostine With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial update evaluating amifostine with or without epoetin alfa in patients with myelodysplastic syndrome.
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CLINICAL_TRIALS research · 2009-03-12Clinical Trial Update: Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS) [Phase 2, Phase 3]
This clinical trial update reports on Phase 2/Phase 3 testing of erythropoietin (epoetin alfa) and granulocyte-colony stimulating factor (fi…
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CLINICAL_TRIALS trial_result · 2009-02-13Clinical Trial Update: Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies [Phase 2]
A Phase 2 clinical trial from St. Jude evaluated haploidentical hematopoietic stem cell transplantation for treatment-refractory hematologic…
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CLINICAL_TRIALS trial_result · 2009-02-09Clinical Trial Update: Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome [Phase 3]
This is a Phase 3 trial evaluating combination chemotherapy with or without idarubicin followed by peripheral stem cell transplantation in p…
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CLINICAL_TRIALS trial_result · 2009-01-26Clinical Trial Update: Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT [Phase 2]
A Phase II trial evaluating busulfan and fludarabine as preparative conditioning therapy in adults with hematopoietic disorders undergoing m…
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CLINICAL_TRIALS trial_result · 2008-12-30Clinical Trial Update: Feasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT) With Fludarabine, Busulfan, and Total Body Irradiation (TBI) [Phase 2]
Phase 2 feasibility and efficacy study of a conditioning regimen using fludarabine, busulfan, and total body irradiation before allogeneic h…
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FDA approval · 2008-08-20FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
FDA approved a supplemental NDA for Vidaza (azacitidine) submitted by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2008-06-25Clinical Trial Update: Safety and Efficacy of Azacitidine, and Thalidomide in Higher Risk MDS (Myelodysplastic Syndrome) [Phase 2]
Phase 2 trial evaluating the safety and efficacy of azacitidine in combination with thalidomide for higher-risk myelodysplastic syndromes.
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EMA withdrawal · 2008-06-04EMA Application withdrawn: Lenalidomide Celgene Europe (lenalidomide) — Celgene Europe Limited
EMA withdrew thelenalidomide Celgene Europe application for myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2008-06-03Clinical Trial Update: Study of TLK199 HCl Liposomes for Injection in Myelodysplastic Syndrome [Phase 1, Phase 2]
Completed Phase 1/2 trial of TLK199 HCl liposomes for injection in myelodysplastic syndromes sponsored by Telik.
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CLINICAL_TRIALS trial_result · 2008-03-13Clinical Trial Update: Study of Velcade and Thalidomide in Patients With Myelodysplasia [Phase 1]
Phase 1 trial of Velcade (bortezomib) and thalidomide in patients with myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome [Phase 2]
This Phase 2 randomized trial comparing antithymocyte globulin to cyclosporine for cytopenia in myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Randomized Trial of Recombinant Humanized Anti-IL-2 Receptor Antibody (Daclizumab) Versus Antithymocyte Globulin (ATG) to Treat the Cytopenia of Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 randomized trial comparing daclizumab (anti-IL-2 receptor antibody) versus antithymocyte globulin for cytopenia in myelodysplastic…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: HLA-Mismatched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating HLA-mismatched peripheral blood stem cell transplantation for hematologic malignancies has completed.
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FDA approval · 2008-02-22FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for VIDAZA (azacitidine) submitted by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2007-05-17Clinical Trial Update: Darbepoetin Alpha in Myelodysplastic Syndromes (MDS) [Phase 2]
Phase 2 clinical trial update assessing darbepoetin alfa in patients with myelodysplastic syndromes; current trial status is unknown.
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CLINICAL_TRIALS trial_result · 2007-04-23Clinical Trial Update: Study of Low Intensity Conditioning and Immunotherapy for High-Risk Cancers of the Blood [Phase 2]
This is a Phase 2 trial update evaluating low-intensity conditioning and immunotherapy for high-risk blood cancers; the study has been termi…
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FDA approval · 2007-04-20FDA Approved: EXJADE — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for EXJADE (deferasirox) submitted by Novartis Pharmaceuticals Corporation, resulting in an approved…