Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-01-19Clinical Trial Update: A Phase II Study of Maintenance With Azacitidine in MDS Patients [Phase 2]
Phase II study evaluating maintenance azacitidine in patients with myelodysplastic syndromes and acute myeloid leukemia; the trial status is…
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CLINICAL_TRIALS trial_result · 2012-01-13Clinical Trial Update: Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS [Phase 2]
This Phase 2 trial studied selective T-cell depletion in stem cell transplantation to reduce graft-versus-host disease. It included patients…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Safety Study of MultiStem® in Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplasia [Phase 1]
This Phase 1 safety study of MultiStem in patients with acute myeloid leukemia, chronic myeloid leukemia, or myelodysplastic syndromes has c…
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CLINICAL_TRIALS trial_result · 2011-12-08Clinical Trial Update: Non-Ablative Allo HSCT For Hematologic Malignancies or SAA [Phase 2]
Phase 2 trial update evaluating non-ablative allogeneic hematopoietic stem cell transplantation for hematologic malignancies and severe apla…
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CLINICAL_TRIALS trial_result · 2011-12-08Clinical Trial Update: A Trial of Bevacizumab in Myelodysplastic Syndromes (Int-1, Int-2 and High Risk According to International Prognostic Scoring System (IPSS)) With Excess of Marrow Blasts [Phase 2]
A Phase 2 trial evaluating bevacizumab in myelodysplastic syndromes with excess marrow blasts has been terminated.
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Bone Marrow Transplantation in Treating Patients With Hematologic Cancer [Phase 2]
This Phase 2 clinical trial update reports on bone marrow transplantation as a treatment for hematologic cancers, including leukemia, lympho…
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Arsenic Trioxide and Etanercept in Treating Patients With Myelodysplastic Syndromes [Phase 1, Phase 2]
This completed Phase 1/2 trial evaluated arsenic trioxide in combination with etanercept for myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation [Phase 2]
This clinical trial update reports results from a Phase 2 study of lymphocyte infusion for patients who relapsed cancer after bone marrow or…
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CLINICAL_TRIALS trial_result · 2011-10-12Clinical Trial Update: Phase 2 Study Comparing Two Dose Schedules of Telintra™ in Myelodysplastic Syndrome (MDS) [Phase 2]
This document reports the results of a Phase 2 trial comparing two dosing schedules of Telintra in patients with myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2011-10-12Clinical Trial Update: A Phase I Study of Lintuzumab Combined With Lenalidomide in Patients With Myelodysplastic Syndromes (MDS) [Phase 1]
Phase I study of lintuzumab combined with lenalidomide in myelodysplastic syndromes has completed enrollment and status is reported as compl…
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CLINICAL_TRIALS trial_result · 2011-08-31Clinical Trial Update: Phase I Trial of Vorinostat (MK-0683, SAHA) in Combination With Decitabine in Patients With AML or MDS (MK-0683-055 EXT1) [Phase 1]
This Phase I clinical trial update reports the combination of Vorinostat (MK-0683, SAHA) with Decitabine in patients with acute myeloid leuk…
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FDA approval · 2011-08-17FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
The FDA approved a supplemental application for Vidaza (azacitidine) submitted by Celgene Corporation, authorizing changes via a supplementa…
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CLINICAL_TRIALS trial_result · 2011-08-17Clinical Trial Update: Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin [Phase 2]
Phase 2 pilot study evaluating reduced-intensity conditioning with fludarabine, busulfan, and thymoglobulin for hematopoietic stem cell tran…
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FDA approval · 2011-08-10FDA Approved: EXJADE — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for EXJADE (deferasirox) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: Umbilical Cord Blood (UCB) Transplant, Fludarabine, Melphalan, and Anti-thymocyte Globulin (ATG) in Treating Patients With Hematologic Cancer [Phase 2]
This is a Phase II clinical trial evaluating an umbilical cord blood transplant using fludarabine, melphalan, and anti-thymocyte globulin in…
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Trial of Decitabine in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial of decitabine in patients with acute myeloid leukemia or myelodysplastic syndrome has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2011-07-15Clinical Trial Update: Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated sirolimus, tacrolimus, and methotrexate to prevent acute graft-versus-host disease in patients with he…
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CLINICAL_TRIALS trial_result · 2011-07-15Clinical Trial Update: Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of idarubicin, cytarabine, and tipifarnib in newly diagnosed myelodysplastic syndromes or acute m…
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CLINICAL_TRIALS trial_result · 2011-07-15Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Myeloid Cancer or Other Disease [Phase 2]
Phase 2 trial update on donor stem cell transplantation for myeloid cancers and related diseases, with terminated status and results posted …
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CLINICAL_TRIALS trial_result · 2011-07-13Clinical Trial Update: A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families [Phase 3]
Phase 3 trial comparing a web-based stem cell transplant support system to standard care in young patients undergoing stem cell transplant a…
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CLINICAL_TRIALS trial_result · 2011-06-30Clinical Trial Update: Oxaliplatin, Fludarabine, and Cytarabine in Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating the combination of oxaliplatin, fludarabine, and cytarabine in patients with acute myeloid leukemia or…
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CLINICAL_TRIALS trial_result · 2011-06-28Clinical Trial Update: Multicentric Study Comparison Between Erythropoietin and Erythropoietin Associated to Differentiating Therapy With Acid 13-cis-retinoic and Dihydroxyvitamin D3 in Myelodysplastic Syndromes Without Excess of Blasts [Phase 3]
A Phase 3 multicenter trial in myelodysplastic syndromes without excess blasts comparing erythropoietin alone to erythropoietin with differe…
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CLINICAL_TRIALS withdrawal · 2011-06-28Clinical Trial Update: Study of Association of Arsenic Trioxide (ATO) and Ascorbic Acid in Myelodysplastic Syndromes [Phase 2]
A Phase 2 trial evaluating the combination of arsenic trioxide and ascorbic acid in myelodysplastic syndromes was terminated.
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CLINICAL_TRIALS trial_result · 2011-05-19Clinical Trial Update: Early Discharge and Outpatient Care After Chemotherapy in Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia [NA]
The trial evaluated early discharge and outpatient chemotherapy care for patients with acute myeloid leukemia or myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2011-05-17Clinical Trial Update: FR901228 in Treating Patients With Myelodysplastic Syndrome, Acute Myeloid Leukemia, or Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 clinical trial evaluating romidepsin (FR901228) in patients with myelodysplastic syndromes, acute myeloid leukemia, or non-Hodgkin l…