Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2012-10-02Clinical Trial Update: Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 study of busulfan and fludarabine conditioning before donor stem cell transplant for hematologic cancers has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer [Phase 2]
Phase 2 trial evaluating early administration of anti-thymocyte globulin (ATG) followed by cyclophosphamide, busulfan and fludarabine as a c…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count [Phase 3]
Phase 3 trial update on preventing infection in patients with hematologic cancers and leukopenia-related fever; the study has been completed…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer [NA]
A clinical trial comparing moxifloxacin with ciprofloxacin plus amoxicillin for fever and neutropenia in cancer patients was terminated.
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CLINICAL_TRIALS trial_result · 2012-09-14Clinical Trial Update: A Study of the Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of the histone-deacetylase inhibitor JNJ-26481585 in patients with advanced or refractory leukemia or myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Low-Intensity Preparation and Allogeneic Transplant in Patients With Cancers of the Blood [Phase 2]
This entry summarizes a Phase 2 trial evaluating low-intensity conditioning followed by allogeneic stem cell transplantation for patients wi…
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB) [Phase 1, Phase 2]
Clinical trial update on a reduced-intensity preparative regimen followed by stem cell transplantation (FAB) in several hematologic malignan…
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating chemotherapy followed by bone marrow transplantation in patients with acute myeloid leukemia or myelodyspl…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Allo Transplantation With Mylotarg, Fludarabine and Melphalan for AML, CML and MDS [Phase 1, Phase 2]
An allogeneic transplant regimen using Mylotarg with fludarabine and melphalan was studied for acute myeloid leukemia, chronic myeloid leuke…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: FTS Study in Patients With Advanced Hematologic Malignancies [Phase 1]
Phase I study update of FTS in patients with advanced hematologic malignancies, including myelodysplastic syndromes and leukemia; the trial …
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Gleevec/Low-Dose Ara-C Study for Elderly Patients With AML and Myelodysplastic Syndromes [Phase 2]
This is a completed Phase 2 clinical trial evaluating Gleevec (imatinib) in combination with low-dose cytarabine for elderly patients with a…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Quality of Life of Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
A completed clinical trial conducted at MD Anderson evaluated quality of life in patients with acute myeloid leukemia or myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating peripheral stem cell transplantation with filgrastim in patients with acute or chronic myeloid leukemia; the study …
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating decitabine with peripheral stem cell transplantation in patients relapsed after bone marrow transplantat…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 clinical trial evaluating the combination of cytarabine and UCN-01 in patients with refractory or relapsed acute myeloid leukemia …
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CLINICAL_TRIALS other · 2012-07-23Clinical Trial Update: Study to Assess OPB-31121 in Advanced Leukemias or Myelodysplastic Syndromes [Phase 1]
Phase 1 trial update showing termination of the study evaluating OPB-31121 in advanced leukemias and myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2012-07-20Clinical Trial Update: Clofarabine, Cytarabine, and Idarubicin in Treating Patients With Intermediate-Risk or High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplasia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a combination of clofarabine, cytarabine, and idarubicin in adults with intermediate- or high-risk acu…
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CLINICAL_TRIALS trial_result · 2012-07-19Clinical Trial Update: A Phase I Trial of ZIO-101 in Hematologic Cancers [Phase 1]
This document reports the completion status of a Phase I trial evaluating ZIO-101 in hematologic cancers sponsored by Alaunos Therapeutics.
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CLINICAL_TRIALS trial_result · 2012-07-18Clinical Trial Update: Study of Temozolomide in Previously Untreated Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Participants With Low O6-Methylguanine Methyltransferase (MGMT) Expression (P05052) [Phase 2]
Phase 2 trial evaluating temozolomide in previously untreated acute myeloid leukemia and myelodysplastic syndrome patients with low MGMT exp…
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematologic Cancer or Myelodysplastic Syndrome [Phase 2]
A Phase 2 clinical trial evaluating donor stem cell transplantation after conditioning with busulfan, fludarabine, and antithymocyte globuli…
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CLINICAL_TRIALS trial_result · 2012-07-16Clinical Trial Update: Idarubicin, Cytarabine, and Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome [Phase 2]
This is a Phase 2 clinical trial evaluating idarubicin, cytarabine, and gemtuzumab ozogamicin in patients with previously untreated high-ris…
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CLINICAL_TRIALS trial_result · 2012-07-16Clinical Trial Update: Infliximab in Treating Patients With Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluated infliximab in patients with myelodysplastic syndromes; the trial sponsored by EORTC has completed.
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CLINICAL_TRIALS withdrawal · 2012-07-11Clinical Trial Update: Monoclonal Antibody Therapy in Treating Patients With Primary Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating monoclonal antibody therapy for myelodysplastic syndromes has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-07-09Clinical Trial Update: Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant [NA]
A clinical trial evaluating mechanical stimulation to prevent bone density loss in patients undergoing donor stem cell transplant has been w…
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CLINICAL_TRIALS trial_result · 2012-06-25Clinical Trial Update: Study of Oral Dasatinib in Subjects With Myelodysplastic Syndrome (MDS) and Excess Marrow Blasts [NA]
A completed study evaluated oral dasatinib in patients with myelodysplastic syndromes with excess marrow blasts. Results were posted in 2012…