Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2024-10-09Clinical Trial Update: A Retrospective Study to Describe Real-World Treatment Patterns and Clinical Outcomes Among Patients With Myelodysplastic Syndromes
This clinical trial update describes a retrospective real-world study of treatment patterns and outcomes in myelodysplastic syndromes, but t…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS) [Phase 2]
Phase 2 study of oral decitabine/cedazuridine in combination with magrolimab for intermediate- to very high-risk myelodysplastic syndromes w…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study of a VA conditioning regimen followed by allogeneic hematopoietic stem cell tra…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: Transfusion in Lower Risk MDS Patients: Predictors of Adequacy of Transfusion and Quality of Life in Lower Risk MDS
This clinical trial update describes a study in lower-risk myelodysplastic syndromes evaluating predictors of transfusion adequacy and the i…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Phase I Study of CYC140, a PLK-1 Inhibitor, in Advanced Leukemias or MDS [Phase 1]
Phase I study of CYC140, a PLK-1 inhibitor, in advanced leukemias and myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory AML or MDS [Phase 1]
This Clinical Trial Update reports that a Phase 1 study of CYC065 in combination with Venetoclax for relapsed or refractory acute myeloid le…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Study of HS-20106 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial evaluating HS-20106 for anemia due to very low, low, or intermediate-risk myelodysplastic syndromes. The study status…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: TMLI Plus Chemotherapy in High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial evaluating total marrow and lymphoid irradiation (TMLI) with chemotherapy for high-risk myelodysplastic syndromes a…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: TMLI/Fludarabine/Melphalan Conditioning for Allogeneic Transplantation in High-risk Myelodysplastic Syndrome or Acute Myeloid Leukemia. [Phase 2]
Phase 2 clinical trial evaluating total marrow irradiation-based conditioning with fludarabine and melphalan for allogeneic transplantation …
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems [Phase 1]
Takeda announced results from a Phase 1 study of pevonedistat in people with blood cancers and solid tumors who also have kidney or liver im…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies [Phase 2]
Phase 2 study evaluating MGTA-145 in combination with Plerixafor for mobilizing hematopoietic stem cells for allogeneic transplantation in h…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating a combination of post-transplant cyclophosphamide, abatacept, vedolizumab, and baricitinib to prevent graft…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS [Phase 1]
Phase 1 trial of CFI-400945 fumarate in relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes has completed.
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation [NA]
This ClinicalTrials.gov update reports a completed feasibility study evaluating an adapted physical activity program for children, adolescen…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Treatment of Anemia in Patients With Very Low, Low or Intermediate Risk Myelodysplastic Syndromes With CA-4948 [Phase 2]
The Phase 2 study of CA-4948 for treating anemia in patients with very low, low or intermediate risk myelodysplastic syndromes has been term…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: A Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies [Phase 1]
Phase 1 clinical trial of TQB3455 tablets for hematological malignancies is currently recruiting in patients with acute myeloid leukemia and…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: VA Combined With PD-1 Inhibitor for the Treatment of Relapsed and Refractory AML and High-risk MDS [Phase 2]
A Phase 2 clinical trial is evaluating the combination of a VA agent with a PD-1 inhibitor for relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Effect of Food on Blood Levels of ASTX727 [Phase 1]
Phase 1 trial evaluating the impact of food on plasma levels of ASTX727 (decitabine/cedazuridine) in patients with myelodysplastic syndromes…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias [Phase 1, Phase 2]
An early-phase study of escalating doses of AT9283 for various leukemias has been terminated.
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome Low Risk [NA]
Clinical trial evaluating allogeneic hematopoietic stem cell transplantation in patients with low-risk myelodysplastic syndromes has complet…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen [Phase 2]
Phase 2 clinical trial evaluating sorafenib as relapse prophylaxis after hematopoietic cell transplantation using the PTBCy regimen; the stu…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Tipifarnib in Subjects With Myelodysplastic Syndromes [Phase 2]
A Phase 2 trial of tipifarnib for myelodysplastic syndromes was terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies [Phase 1]
Phase 1 study of AMG 330 in adults with myeloid malignancies, including relapsed/refractory acute myeloid leukemia and MRD-positive AML, has…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes
This clinical trial update describes ongoing efforts to collect and store blood, bone marrow, and other samples from patients with acute leu…