Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Guadecitabine in Treating Patients With Higher-Risk Myelodysplastic Syndromes [Phase 2]
A Phase 2 trial of guadecitabine in higher-risk myelodysplastic syndromes has been completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS [Phase 2]
Phase 2 trial status update for CPX-351 in older patients with refractory or relapsed acute myeloid leukemia and myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia [Phase 1]
A Phase 1 study evaluating AMG 176 in combination with azacitidine in higher-risk myelodysplastic syndromes and chronic myelomonocytic leuke…
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EMA approval · 2025-07-11EMA Authorised: Epoetin Alfa Hexal (epoetin alfa) — Hexal AG
The EMA authorised Epoetin Alfa Hexal (epoetin alfa) from Hexal AG to treat anemia associated with chronic kidney disease and related condit…
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EMA approval · 2025-07-11EMA Authorised: Binocrit (epoetin alfa) — Sandoz GmbH
EMA authorised Binocrit (epoetin alfa) by Sandoz GmbH for the treatment of anemia associated with chronic kidney disease, myelodysplastic sy…
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EMA approval · 2025-07-11EMA Authorised: Abseamed (epoetin alfa) — Medice Arzneimittel Pütter GmbH Co. KG
EMA has authorised Abseamed, an epoetin alfa product by Medice, for treatment of anemia associated with chronic kidney disease and certain h…
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CLINICAL_TRIALS other · 2025-07-10Clinical Trial Update: FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies [Phase 1]
Phase 1 trial update for FHD-286 as monotherapy or in combination in adults with advanced hematologic malignancies. The study is currently a…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study
A feasibility pilot study evaluating the use of the OURA Ring wearable in patients with myelodysplastic syndromes to explore discovery endpo…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
This clinical trial update describes the use of the PET imaging agent 18F-fluorothymidine (18F-FLT) in cancer patients to assess tumor proli…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: A Randomized Phase II Study of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplant [Phase 2]
A Phase II randomized trial evaluating hyperbaric oxygen to improve engraftment after umbilical cord blood stem cell transplantation in pati…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Eltrombopag as a Novel Therapeutic Approach for Low-risk MDS and CMML With TET2 Mutations [Phase 2]
Phase 2 clinical trial evaluating eltrombopag as a treatment for low-risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia with…
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CLINICAL_TRIALS other · 2025-07-03Clinical Trial Update: Connect® Myeloid Disease Registry
The Connect Myeloid Disease Registry sponsored by Celgene has been terminated. The registry involved conditions including primary myelofibro…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation [Phase 2]
Phase 2 trial evaluating maintenance therapy with ivosidenib after allogeneic stem cell transplantation in patients with acute myeloid leuke…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of combining hydroxyurea with valproic acid or 6-mercaptopurine with valproic acid in…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML [Phase 1]
Phase 1 clinical trial update for GTB-3650 Trike in high-risk myeloid malignancies, including acute myeloid leukemia and myelodysplastic syn…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of oral LY3410738 in patients with IDH1/IDH2-mutant hematologic malignancies is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 clinical trial evaluating intensity-modulated total marrow irradiation in fully matched and partially matched allogeneic transplan…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Registry of Older Patients With Cancer
This clinical trial registry entry from UNC Lineberger indicates an ongoing recruitment for a registry of older patients with cancer, includ…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers [Phase 2]
Phase 2 study of E7820 in people with bone marrow (myeloid) cancers, including Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Chroni…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome
A clinical trial by Minovia Therapeutics collecting bone marrow aspiration samples from patients with myelodysplastic syndromes; the study s…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes [Phase 1]
A Phase 1 dose-finding study of CC-90009 in adults with relapsed or refractory acute myeloid leukemia or relapsed/refractory higher-risk mye…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy
This document outlines a clinical trial protocol to genomically profile, collect, archive, and distribute blood and bone marrow specimens fr…