Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Study Investigating the Interactions of Bone and Hematopoiesis in the Elderly
A completed clinical trial from Technische Universität Dresden explored the interactions between bone biology and hematopoiesis in elderly i…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: A Study to Evaluate Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Patients With Lower-Risk Myelodysplastic Syndromes Treated With Luspatercept
This completed clinical trial update evaluates treatment patterns, outcomes, and healthcare resource utilization in patients with lower-risk…
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CLINICAL_TRIALS other · 2025-08-20Clinical Trial Update: QH101 Cell Therapy Relapsed/Refractory(R/R) Acute Myeloid Leukemia(AML) and Myelodysplastic Syndromes(MDS) [Phase 1]
Phase 1 clinical trial update for QH101 Cell Therapy in relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes; the study …
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell [Phase 1, Phase 2]
A completed Phase 1/2 study from Stanford evaluated a haploidentical hematopoietic cell transplantation approach using a T-cell depleted gra…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy [Phase 3]
A Phase 3 trial assessing ivosidenib plus azacitidine with or without venetoclax in adults with newly diagnosed IDH1-mutated AML or MDS/AML …
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: A Study of GLB-001 in Patients With Myeloid Malignancies [Phase 1]
A Phase 1 clinical trial evaluating GLB-001 in patients with myeloid malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating iadademstat in combination with azacitidine and venetoclax for newly diagnosed acute myeloid leukemia; recruitment …
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation [Phase 1]
A Phase 1 dose-escalation study of vorinostat after allogeneic hematopoietic cell transplantation is ongoing.
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Muscle Dysfunction in Patients With Haematological Diseases
This clinical trial update describes a study on muscle dysfunction in patients with hematologic diseases, including acute myeloid leukemia, …
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients [Phase 1, Phase 2]
A Phase 1/2 trial evaluating luspatercept in combination with lenalidomide (L2) for lower-risk non-del(5q) myelodysplastic syndromes has bee…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS) [Phase 1]
Phase 1 clinical trial evaluating venetoclax in combination with azacitidine in treatment-naïve, higher-risk myelodysplastic syndromes is on…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies
This study evaluates frailty phenotype assessments to optimize treatment strategies for older patients with hematologic malignancies. It is …
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Oral Arsenic (ATO) in Low-risk Myelodysplastic Syndromes (MDS) [Phase 1]
A Phase 1 clinical trial evaluating oral arsenic (arsenic trioxide) for low-risk myelodysplastic syndromes is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating an allogeneic engineered hematopoietic stem cell transplant lacking CD33, with post-transplant Mylotarg,…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating 225Ac-DOTA-Anti-CD38 (daratumumab radiolabeled with Actinium-225) in combination with fludarabine, melphal…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT) [NA]
Clinical trial update for ACT evaluating compassionate communication and advance care planning to improve end-of-life care in hematologic di…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Assesment of the Immune Response to RSV Vaccine in Patients With Myeloma, Lymphoma and Hematological Leukemia
This clinical trial update assesses the immune response to an RSV vaccine in patients with hematologic cancers, including multiple myeloma, …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Reduced ATG Plus Mini PTCy for GVHD Prophylaxis in Haplo-SCT [Phase 2]
Phase 2 trial evaluating reduced ATG plus mini post-transplant cyclophosphamide for graft-versus-host disease prophylaxis in haploidentical …
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML) [Phase 1]
Phase 1 trial update evaluating haploidentical donor natural killer cell infusion with IL-15 in patients with acute myeloid leukemia and mye…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant [NA]
This study update notes that a trial investigating cognitive outcomes in older adults receiving stem cell transplant is currently in RECRUIT…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Study of Evorpacept (ALX148) With Azacitidine for Higher Risk Myelodysplastic Syndrome (ASPEN-02) [Phase 1]
This document reports the termination of the Phase 1 ASPEN-02 trial evaluating evorpacept (ALX148) in combination with azacitidine for highe…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Treatment Patterns and Outcomes in Patients With Lower-risk Myelodysplastic Syndromes Treated With Luspatercept in China
This clinical trial update reviews treatment patterns and outcomes for lower-risk myelodysplastic syndrome patients treated with luspatercep…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Mosaic Trial for Stem Cell Transplant Recipients [NA]
This clinical trial update indicates the Mosaic trial for stem cell transplant recipients is currently recruiting.