Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDS [Phase 2]
Phase 2 trial update of multi-modality treatment with Ruxolitinib, Decitabine, and donor lymphocyte infusion after stem cell transplant in A…
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: A Study of Pevonedistat in Adult East Asian Participants [Phase 1]
Phase 1 trial update of pevonedistat in adult East Asian participants has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With Higher-risk MDS [Phase 2]
Phase 2 trial exploring safety and efficacy of unrelated umbilical cord blood microtransplantation in higher-risk myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: HCT With PTCy in Higher-risk MDS [Phase 2]
Phase 2 clinical trial evaluating haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide in higher-risk mye…
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: CyFluATG in Lower Risk MDS [Phase 2]
Phase 2 clinical trial update for CyFluATG in lower risk myelodysplastic syndromes (MDS) shows the study is active but not currently recruit…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Hematopoietic Cell Transplantation With Post-transplantation Cyclophosphamide in MDS [Phase 2]
Phase 2 clinical trial evaluating hematopoietic cell transplantation with post-transplant cyclophosphamide for myelodysplastic syndromes has…
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: A Study to Evaluate the Efficacy, Drug Levels and Safety of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in Chinese and Japanese Participants With Ring Sideroblasts Who Require Red Blood Cell Transfusions [Phase 2]
Phase 2 study evaluating efficacy, drug levels, and safety of luspatercept (ACE-536) for anemia due to IPSS-R very low/low/intermediate risk…
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Busulfan, Etoposide, and Total-Body Irradiation in Treating Patients Undergoing Donor Stem Cell or Bone Marrow Transplant for Advanced Hematologic Cancer [Phase 2]
Phase 2 study evaluating a conditioning regimen of busulfan, etoposide, and total-body irradiation for patients undergoing donor stem cell o…
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CLINICAL_TRIALS trial_result · 2023-10-03Clinical Trial Update: Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial exploring repurposed drugs to improve hematological responses in myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis [Phase 3]
Phase 3 clinical trial evaluating a post-transplant immunomodulatory regimen (cyclophosphamide, abatacept, vedolizumab, and a calcineurin in…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Methods of T Cell Depletion Trial (MoTD) [Phase 2]
Phase 2 trial update for methods of T cell depletion in various hematologic malignancies is ongoing.
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study [Phase 1, Phase 2]
Long-term follow-up update from BP-004 study (Phase 1/Phase 2) by Bellicum Pharmaceuticals; study status TERMINATED with results posted in 2…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Allo HSCT Using RIC for Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning for various hematologic dise…
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CLINICAL_TRIALS trial_result · 2023-09-01Clinical Trial Update: Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDS [Phase 2, Phase 3]
A study comparing Haplo-HSCT with Rivogenlecleucel versus Haplo-HSCT with post-transplant cyclophosphamide in AML or MDS was terminated with…
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CLINICAL_TRIALS trial_result · 2023-08-23Clinical Trial Update: Roxadustat Combined With Luspatercept Versus Luspatercept Monotherapy in the Treatment of Refractory MDS-RS [Phase 4]
Phase 4 trial comparing roxadustat combined with luspatercept versus luspatercept alone in refractory myelodysplastic syndromes with ring si…
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CLINICAL_TRIALS trial_result · 2023-08-22Clinical Trial Update: Efficacy and Safety of Lenalidomide Combined With Azacitidine vs Azacitidine in the Treatment of MDS-RS [Phase 4]
A Phase 4 trial evaluating lenalidomide plus azacitidine versus azacitidine alone in myelodysplastic syndromes with ring sideroblasts.
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Treatment of MDS/AML Patients With an Impending Hematological Relapse With AZA or ATA and Pevonedistat [Phase 2]
Phase 2 clinical trial evaluating azacitidine or ATA in combination with pevonedistat for MDS/AML patients at impending hematological relaps…
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CLINICAL_TRIALS trial_result · 2023-08-16Clinical Trial Update: Decitabine and Arsenic Trioxide for Myelodysplastic Syndrome(MDS) [Phase 3]
Phase 3 clinical trial investigating decitabine and arsenic trioxide for myelodysplastic syndromes with P53 mutation was withdrawn.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: A Study of ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS) [Phase 1, Phase 2]
Phase 1/2 trial evaluating ARGX-110 with azacytidine in newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndromes has co…
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CLINICAL_TRIALS trial_result · 2023-07-07Clinical Trial Update: A Study of MBG453 in Combination With Hypomethylating Agents in Subjects With IPSS-R Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS). [Phase 2]
Phase 2 study of MBG453 in combination with hypomethylating agents for intermediate/high/very high risk myelodysplastic syndrome; the trial …
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1, Phase 2]
Clinical trial update for IMM01 combined with azacitidine in acute myeloid leukemia and myelodysplastic syndromes, currently in Phase 1 and …
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CLINICAL_TRIALS trial_result · 2023-05-18Clinical Trial Update: Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs [Phase 3]
Phase 3 trial evaluating guadecitabine (SGI-110) vs treatment choice in adults with myelodysplastic syndromes or chronic myelomonocytic leuk…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders [Phase 2]
Phase 2 clinical trial update on donor peripheral stem cell transplantation for patients with advanced hematologic cancers and related disor…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Helical Tomotherapy, Fludarabine Phosphate, and Melphalan Followed By Allo-HSCT in Hematological Malignancies [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update evaluating a conditioning regimen of Helical Tomotherapy with fludarabine phosphate and melphalan foll…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Myeloid Leukemia and Myelodysplastic Syndromes Undergoing Allo-HSCT [Phase 2]
A Phase 2 clinical trial evaluating a conditioning regimen combining venetoclax, azacytidine, and a modified BUCY approach for patients with…