Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Treatment Patterns and Outcomes in Patients With Lower-risk Myelodysplastic Syndromes Treated With Luspatercept in China
This clinical trial update reviews treatment patterns and outcomes for lower-risk myelodysplastic syndrome patients treated with luspatercep…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Guadecitabine in Treating Patients With Higher-Risk Myelodysplastic Syndromes [Phase 2]
A Phase 2 trial of guadecitabine in higher-risk myelodysplastic syndromes has been completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS [Phase 2]
Phase 2 trial status update for CPX-351 in older patients with refractory or relapsed acute myeloid leukemia and myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia [Phase 1]
A Phase 1 study evaluating AMG 176 in combination with azacitidine in higher-risk myelodysplastic syndromes and chronic myelomonocytic leuke…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers [Phase 2]
Phase 2 study of E7820 in people with bone marrow (myeloid) cancers, including Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Chroni…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes [Phase 1]
A Phase 1 dose-finding study of CC-90009 in adults with relapsed or refractory acute myeloid leukemia or relapsed/refractory higher-risk mye…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Palifermin (Kepivance) in patients undergoing unrelated donor allogeneic hematopoietic cell transplant…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT [Phase 2]
Phase 2 clinical trial evaluating interferon-α for TP53-mutant myeloid malignancies after allogeneic stem cell transplantation is currently …
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: A Study of JNJ-67571244 in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 study of JNJ-67571244 in relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: RVU120 for Treatment of Anemia in Patients With Lower-risk Myelodysplastic Neoplasms [Phase 2]
Phase 2 trial update for RVU120 in anemia associated with lower-risk myelodysplastic syndromes. The study status is ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: BST-236 as a Single Agent in Adults With Relapsed or Refractory AML or HR-MDS [Phase 2]
Phase 2 trial evaluating BST-236 as a single-agent therapy in adults with relapsed or refractory acute myeloid leukemia or high-risk myelody…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: IDH2 (AG 221) Inhibitor in Patients With IDH2 Mutated Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial update for the IDH2 inhibitor AG-221 (enasidenib) in IDH2-mutated myelodysplastic syndrome; the study is active but n…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrome [Phase 2]
Phase 2 trial of the IDH1 inhibitor ivosidenib (AG-120) in IDH1-mutated myelodysplastic syndromes (also listed for acute myeloid leukemia); …
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: ASTX727 and Donor Lymphocyte Infusions After Allogenic Stem Cell Transplantation in Very High Risk MDS or AML Patients [Phase 2]
Phase 2 trial evaluating ASTX727 with donor lymphocyte infusions after allogeneic stem cell transplantation in very high risk myelodysplasti…
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CLINICAL_TRIALS trial_result · 2025-05-11Clinical Trial Update: Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab [Phase 1]
Phase 1 study evaluating pembrolizumab to augment graft-versus-leukemia effect in patients with myelodysplastic syndromes and acute myeloid …
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation [Phase 2]
Phase 2 trial evaluating tocilizumab to prevent graft-versus-host disease after cord blood transplantation has been completed.
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Tamibarotene Plus Azacitidine in Participants With Newly Diagnosed RARA-positive Higher-Risk Myelodysplastic Syndrome [Phase 3]
A Phase 3 trial evaluating tamibarotene plus azacitidine in newly diagnosed RARA-positive higher-risk myelodysplastic syndromes was terminat…
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CLINICAL_TRIALS trial_result · 2025-04-07Clinical Trial Update: Comparing Two Diets in Patients Undergoing HSCT or Remission Induction Chemo for Acute Leukemia and MDS (UF-BMT-LDND-101) [Phase 3]
A Phase 3 clinical trial comparing two dietary interventions in patients undergoing hematopoietic stem cell transplant or remission inductio…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation [Phase 1]
Phase 1 study evaluating itacitinib for prophylaxis of graft-versus-host disease and cytokine release syndrome after T-cell replete haploide…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Observational Study Towards the Impact of Newly Started Treatment in MDS on QoL
This completed observational study assessed the impact of newly started treatment on quality of life in patients with myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: Study of FF-10501-01 in Patients With Relapsed or Refractory Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 study of FF-10501-01 in relapsed or refractory hematologic malignancies has completed, with results posted. The diseases studied i…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Biologically Focused Therapy of Treatment-Refractory MDS Patients
The clinical trial evaluating a biologically focused therapy for treatment-refractory myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: A Non-interventional Study of REVLIMID® (Lenalidomide) Treatment of IPSS Low- or Intermediate-1-risk Myelodysplastic Syndromes Associated With a Deletion 5q or Refractory/Relapsed Mantle Cell Lymphoma in Korea
A completed non-interventional study in Korea assessing lenalidomide (REVLIMID) for IPSS low- or intermediate-1-risk myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning with fludarabine and melphalan plus total body irradiation for haploidentical stem c…