Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Resiliency in Older Adults Undergoing Bone Marrow Transplant
A completed clinical trial update from Johns Hopkins on resiliency in older adults undergoing bone marrow transplant for hematologic cancers…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Pilot, Open-Label Study of Luspatercept for Patients With Lower Risk Myelodysplastic Syndromes (MDS) [Phase 2]
Phase 2, open-label pilot study of luspatercept for lower-risk myelodysplastic syndromes is currently recruiting at MD Anderson Cancer Cente…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: CD8 Depleted, Non-engrafting, HLA Mismatched Unrelated Infusion With MDS and Secondary AML [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a CD8-depleted, non-engrafting, HLA-mismatched unrelated donor infusion in patients with myelodysplastic…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS) [Phase 2]
Phase 2 study of etavopivat for anemia in patients with very low to intermediate risk myelodysplastic syndromes was terminated; results have…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: To Assess the Safety and Tolerability of INCB000928 in Participants With Myelodysplastic Syndromes or Multiple Myeloma [Phase 1, Phase 2]
This clinical trial update reports the termination of a Phase 1/2 study of INCB000928 in myelodysplastic syndromes and multiple myeloma, wit…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML [Phase 1]
Phase 1 clinical trial update evaluating eganelisib as a monotherapy and in combination with cytarabine in relapsed/refractory acute myeloid…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS [Phase 1]
A Phase Ib study evaluating select drug combinations in lower-risk myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CPI-0610 with and without ruxolitinib in patients with hematologic and myeloproliferative malignancies. …
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: A Study of JNJ-74856665 in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 study of JNJ-74856665 in participants with Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Chronic Myelomonocytic Leukemia has…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML) [Phase 2]
Phase 2 trial ACHIEVE evaluating adoptive cellular therapy with ex-vivo expanded allogeneic γδ T-lymphocytes (TCB008) for refractory or rela…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Assessment of Effectiveness and Safety of Luspatercept in Patients Suffering From Lower-risk Myelodysplastic Syndrome. [Phase 3]
This document provides a status update on a Phase 3 clinical trial evaluating the effectiveness and safety of Luspatercept in patients with …
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: A Study to Assess the Effect of CC-95251 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndromes [Phase 1]
This Phase 1 trial update reports results for CC-95251 in acute myeloid leukemia and myelodysplastic syndromes. The study has been terminate…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST Study
The CREST study update shows the cardiovascular reserve evaluation trial in transplant survivors is currently active but not recruiting, spo…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of SGR-2921 in relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Study to Evaluate Safety and Tolerability of CC-91633 (BMS-986397) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-Risk Myelodysplastic Syndromes [Phase 1]
Phase 1 study evaluating safety and tolerability of CC-91633 (BMS-986397) in participants with relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia [Phase 2]
This Phase 2 trial examines hematopoietic stem cell transplantation for infant leukemia and has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Study Investigating the Interactions of Bone and Hematopoiesis in the Elderly
A completed clinical trial from Technische Universität Dresden explored the interactions between bone biology and hematopoiesis in elderly i…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell [Phase 1, Phase 2]
A completed Phase 1/2 study from Stanford evaluated a haploidentical hematopoietic cell transplantation approach using a T-cell depleted gra…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients [Phase 1, Phase 2]
A Phase 1/2 trial evaluating luspatercept in combination with lenalidomide (L2) for lower-risk non-del(5q) myelodysplastic syndromes has bee…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating an allogeneic engineered hematopoietic stem cell transplant lacking CD33, with post-transplant Mylotarg,…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating 225Ac-DOTA-Anti-CD38 (daratumumab radiolabeled with Actinium-225) in combination with fludarabine, melphal…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML) [Phase 1]
Phase 1 trial update evaluating haploidentical donor natural killer cell infusion with IL-15 in patients with acute myeloid leukemia and mye…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: A Study of Evorpacept (ALX148) With Azacitidine for Higher Risk Myelodysplastic Syndrome (ASPEN-02) [Phase 1]
This document reports the termination of the Phase 1 ASPEN-02 trial evaluating evorpacept (ALX148) in combination with azacitidine for highe…