Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase [Phase 2]
A Phase 2 trial evaluating CCI-779 (temsirolimus) in adults with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemia…
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: BMS-214662 in Treating Patients With Acute Leukemia, Myelodysplastic Syndrome, or Chronic Myeloid Leukemia [Phase 1]
Phase 1 study of BMS-214662 in patients with various leukemias and myelodysplastic syndromes has completed enrollment; the document lists th…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer [Phase 3]
Phase 3 trial evaluating whether St. John's Wort can relieve fatigue in cancer patients undergoing chemotherapy or hormone therapy has compl…
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Sodium Salicylate in Treating Patients With Advanced Myelodysplastic Syndrome, Acute Myelogenous Leukemia, or Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 trial evaluating sodium salicylate in patients with advanced myelodysplastic syndromes, acute myeloid leukemia, or chronic lymphoc…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial evaluating combination chemotherapy with or without bone marrow transplantation in children with acute myeloid leukemia or mye…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial update evaluating a vaccine therapy for patients with myelodysplastic syndromes. The conditions list also includes le…
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CLINICAL_TRIALS trial_result · 2013-01-11Clinical Trial Update: SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes [Phase 1]
This Phase 1 trial evaluated SB-715992 in adults with various acute leukemias, chronic myeloid leukemia in blast phase, and advanced myelody…
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CLINICAL_TRIALS trial_result · 2013-01-10Clinical Trial Update: Lenalidomide and Recombinant Human Stem Cell Factor for Treatment of Myelodysplasia [EARLY_Phase 1]
This document describes an early-phase 1 clinical trial evaluating lenalidomide in combination with recombinant human stem cell factor for t…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete Remission Following Induction And/Or Consolidation Chemotherapy In Adults With Poor-Risk Acute Myelogenous Leukemia (AML) And High-Risk Myelodysplasia (MDS) [Phase 2]
This status update describes results from a Phase II study of the farnesyltransferase inhibitor tipifarnib (Zarnestra) in adults with poor-r…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Clofarabine for Myelodysplastic Syndrome (MDS) Patients Who Failed Vidaza Treatment (tx) [Phase 2]
A Phase 2 trial of clofarabine in myelodysplastic syndrome patients who failed Vidaza was terminated, with results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer [Phase 1]
Phase 1 study assessing the safety of adding sargramostim (GM-CSF) to chemotherapy in patients with refractory myeloid cancers; the trial ha…
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Vorinostat and Decitabine in Treating Patients With Relapsed, Refractory, or Poor-Prognosis Hematologic Cancer or Other Diseases [Phase 1]
This Phase 1 trial evaluates the safety and feasibility of combining vorinostat with decitabine in adults with relapsed, refractory, or poor…
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Vaccine Therapy Plus Immune Adjuvant in Treating Patients With Chronic Myeloid Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [Phase 1, Phase 2]
This update summarizes a Phase 1/2 clinical trial of a vaccine therapy with an immune adjuvant in patients with chronic myeloid leukemia, ac…
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CLINICAL_TRIALS trial_result · 2012-12-21Clinical Trial Update: Azacitidine Plus Amifostine in Treating Patients With Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating azacitidine plus amifostine in patients with myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2012-12-19Clinical Trial Update: LBH589 in Refractory Myelodysplastic Syndromes (MDS) [Phase 2]
Phase 2 trial of LBH589 in refractory myelodysplastic syndromes was terminated with posted results in 2012.
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: Sibling and Unrelated Donor Hematopoietic Cell Transplant in Hematologic Malignancies [NA]
A completed clinical trial evaluating hematopoietic cell transplantation from sibling and unrelated donors in patients with hematologic mali…
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation [Phase 2]
This update reports the termination of a Phase 2 clinical trial investigating removal of T cells to prevent graft-versus-host disease in bon…
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CLINICAL_TRIALS trial_result · 2012-11-12Clinical Trial Update: Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease [Phase 1]
Phase 1 trial evaluating donor stem cell transplantation in young patients with congenital amegakaryocytic thrombocytopenia, leukemia, myelo…
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia
This clinical trial evaluated non-myeloablative allogeneic stem cell transplantation with matched unrelated donors across several hematologi…
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 trial update evaluating zoledronic acid to prevent osteoporosis in patients undergoing donor stem cell transplantation. The study in…
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CLINICAL_TRIALS trial_result · 2012-10-25Clinical Trial Update: Donor Bone Marrow Transplant in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders [Phase 2]
A Phase 2 clinical trial evaluating donor bone marrow transplantation for various hematologic diseases has completed.
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CLINICAL_TRIALS trial_result · 2012-10-16Clinical Trial Update: Head to Head Comparison of Azacitidine and Decitabine in Myelodysplastic Syndrome
A completed clinical trial comparing azacitidine with decitabine in myelodysplastic syndromes, sponsored by Seoul National University Hospit…
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CLINICAL_TRIALS trial_result · 2012-10-10Clinical Trial Update: Total-Body Irradiation, Fludarabine, and Alemtuzumab Followed By Stem Cell Transplant in Treating Patients With Myeloproliferative Disorder, MS, AML, or CML [Phase 2]
Phase 2 clinical trial evaluating total-body irradiation with fludarabine and alemtuzumab followed by stem cell transplant in patients with …
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CLINICAL_TRIALS trial_result · 2012-10-04Clinical Trial Update: Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer [NA]
A clinical trial update reports completion of a donor stem cell transplant study in older or frail patients with hematologic cancers.
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CLINICAL_TRIALS trial_result · 2012-10-01Clinical Trial Update: Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer [Phase 2]
Phase 2 trial evaluating early administration of anti-thymocyte globulin (ATG) followed by cyclophosphamide, busulfan and fludarabine as a c…