Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of pevonedistat in combination with belinostat for relapsed or refractory acute myeloid leukemia or myelodysplastic syndromes …
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome [Phase 2]
This Phase 2 trial of CD34+ enriched transplants to treat myelodysplastic syndromes is currently suspended.
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: MBG453 in Lower Risk MDS [Phase 2]
A Phase 2 trial of MBG453 for lower-risk myelodysplastic syndromes has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Evaluate Luspatercept Treatment Patterns and Outcomes in Erythropoiesis-Stimulating Agents-Naïve Patients With Lower-Risk Myelodysplastic Syndromes in the United States
The completed study, sponsored by Bristol-Myers Squibb, evaluates luspatercept treatment patterns and outcomes in ESA-naïve patients with lo…
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CLINICAL_TRIALS trial_result · 2026-02-13Clinical Trial Update: Interferon γ-Primed Mesenchymal Stromal Cells as Prophylaxis for Acute Graft v Host Disease [Phase 1]
Phase 1 trial evaluating interferon-γ-primed mesenchymal stromal cells as prophylaxis for acute graft-versus-host disease in patients with a…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: DR-18 for the Treatment of Relapsed or Persistent Acute Myeloid Leukemia or Myelodysplastic Syndrome After Hematopoietic Cell Transplantation, the DR. DREAM Trial [Phase 1]
Phase 1 trial DR-18 for relapsed or persistent acute myeloid leukemia or myelodysplastic syndrome after hematopoietic cell transplantation i…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations
A multicenter observational study assessing myocardial iron overload in three transfused populations has completed, focusing on patients wit…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms. [Phase 1]
A Phase 1 clinical trial of BYON4413 in relapsed/refractory acute myeloid leukemia and myelodysplastic neoplasms reports safety, pharmacokin…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: ONC-201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant [Phase 1]
Phase 1 trial of ONC-201 as maintenance therapy after stem cell transplant in acute myeloid leukemia and myelodysplastic syndromes has compl…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Removing Transfusion Dependence as a Barrier to Hospice Enrollment [NA]
A completed clinical trial update indicates that transfusion dependence was removed as a barrier to hospice enrollment for patients with hem…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) [NA]
A completed clinical trial update reporting long-term outcomes of alternative donor allogeneic transplantation across multiple hematologic d…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT [Phase 1]
Phase 1 trial evaluating a combination of CD25/Treg-depleted donor lymphocyte infusion with ipilimumab for relapse of myeloid diseases after…
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CLINICAL_TRIALS trial_result · 2026-01-02Clinical Trial Update: Efficiency of Antibacterial Prophylaxis in Azacitidine Treated Patients [Phase 3]
Phase 3 trial evaluating antibacterial prophylaxis in azacitidine-treated patients has completed.
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe. [Phase 1, Phase 2]
A Phase 1/2 clinical trial is testing an improved dose of UM171 to enhance the effectiveness and safety of cord blood transplantation; recru…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation [Phase 1, Phase 2]
Phase 1/2 trial evaluating GVHD prophylaxis with post-transplant cyclophosphamide plus sirolimus and VIC-1911 in myeloablative peripheral bl…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS [Phase 1]
Phase 1 study of JNJ-64619178, a PRMT5 inhibitor, in participants with advanced solid tumors, Non-Hodgkin Lymphoma, and lower-risk myelodysp…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects [Phase 1]
Phase 1 study evaluating single and multiple dose administration of LP-001 in healthy subjects has completed.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) [Phase 1, Phase 2]
The first-in-human study of SAR443579 in children and adults with relapsed or refractory acute myeloid leukemia, acute lymphoblastic leukemi…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2) [Phase 3]
Phase 3 study evaluating MBG453 in combination with azacitidine in adults with intermediate/high/very high risk myelodysplastic syndromes (p…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy [Phase 2]
Phase 2 trial evaluating the combination of sirolimus and azacitidine in adults with high-risk myelodysplastic syndrome or acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Real-World Practice Patterns and Outcomes of Lower-Risk Myelodysplastic Syndrome Patients in Japan
This completed clinical trial examines real-world treatment patterns and outcomes for patients with myelodysplastic syndromes, focusing on l…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/Phase 2 trial of eltanexor with Inqovi in high-risk myelodysplastic syndromes was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine [Phase 1]
A Phase 1 clinical trial evaluating a haploidentical bone marrow transplant using post-transplant cyclophosphamide and bendamustine has comp…
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CLINICAL_TRIALS trial_result · 2025-11-04Clinical Trial Update: IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial evaluating maintenance therapy with the IDH1 inhibitor ivosidenib after allogeneic stem cell transplantation in IDH1-mutant my…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion [NA]
Clinical trial update from Baylor College of Medicine reports results for haploidentical hematopoietic cell transplantation using TCR alpha/…