Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-25Clinical Trial Update: LBH589 Alone or in Combination With Erythropoietin Stimulating Agents (ESA) in Patients With Low or Int-1 Risk Myelodysplastic Syndromes (MDS) [Phase 2]
A Phase 2 trial evaluated LBH589 (panobinostat) alone or with erythropoietin-stimulating agents in low- or Int-1 risk myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: Alemtuzumab and Combination Chemotherapy Followed By Donor Lymphocytes in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer [Phase 1]
Phase 1 study evaluating alemtuzumab with combination chemotherapy followed by donor lymphocyte infusion in patients undergoing donor stem c…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Long Term Safety Study of SyB C-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS) - Extension Study [Phase 1]
This report provides long-term safety results from an extension Phase 1 study of SyB C-1101 in patients with recurrent/relapsed or refractor…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder [Phase 3]
Phase 3 trial evaluating cyclosporine eye drops to prevent eye graft-versus-host disease in patients after donor stem cell transplant for he…
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Safety, Tolerability, and Efficacy of Deferasirox in MDS [Phase 3]
Phase 3 trial evaluating safety, tolerability, and efficacy of deferasirox in myelodysplastic syndromes, focusing on iron chelation in patie…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms [Phase 2]
Phase 2 clinical trial update studying molecular and genetic abnormalities in patients with myeloid neoplasms, including Acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Lenalidomide in Subject With Low and Intermediate-1 Risk MDS and Without Chromosome 5 Abnormality. [Phase 2]
A completed Phase 2 trial evaluating lenalidomide in patients with low- and intermediate-1 risk myelodysplastic syndromes without chromosome…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: GFM-Acadesine: A Phase I-II Trial of Acadesine [Phase 1, Phase 2]
A Phase 1/2 trial evaluating acadesine (GFM-Acadesine) for myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This Phase 1/2 clinical trial evaluated the combination of LBH589 (panobinostat) and decitabine in patients with acute myeloid leukemia or m…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: High-Tc Susceptometer to Monitor Transfusional Iron Overload
Clinical trial update reporting that the study evaluating a High-Tc Susceptometer to monitor transfusional iron overload has completed, in p…
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Phase I Study Evaluating TXA127 in Low/Intermediate-1 Risk Myelodysplastic Syndrome and Thrombocytopenia [Phase 1]
A Phase I study of TXA127 in patients with low/intermediate-1 risk myelodysplastic syndromes and thrombocytopenia was terminated.
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Umbilical Cord Blood Transplant for Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating umbilical cord blood transplantation for hematologic malignancies has completed enrollment and reporting.
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Immunotherapy for Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Blast Phase Chronic Myelogenous Leukemia (BP CML), and Myelodysplastic Syndrome (MDS) Relapse After Allogeneic Transplantation [Phase 2]
Phase 2 trial update evaluating immunotherapy for relapse after allogeneic transplantation in acute myeloid leukemia, acute lymphoblastic le…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia [Phase 1]
This is a Phase 1 ascending-dose study of KW-2449 in patients with acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: Sitagliptin Umbilical Cord Blood Transplant Study [Phase 2]
Phase 2 clinical trial update on sitagliptin in the setting of umbilical cord blood transplantation, with results posted in 2016 for several…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Topotecan in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating topotecan in patients with myelodysplastic syndromes has completed. The study also included patients with leukemia.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders [Phase 2]
A Phase 2 trial testing nonmyeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors for multiple hematologic dis…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: Microtransplantation With Decitabine and Cytarabine Improves Patient Outcomes in Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 clinical trial reports results for microtransplantation with decitabine and cytarabine in myelodysplastic syndromes, noting improv…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment [Phase 3]
Phase 3 trial evaluating ondansetron for chronic nausea and vomiting in patients with advanced cancer not caused by cancer treatment; the st…
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: 506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment [Phase 1]
Phase 1 trial of the agent 506U78 in patients with hematologic cancers and kidney or liver impairment; the study has terminated.
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer [Phase 2]
A Phase 2 clinical trial evaluating donor stem cell transplantation for patients with relapsed hematologic cancers has completed.
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemia [Phase 1, Phase 2]
A completed Phase 1/2 safety study evaluating CLT-008 (human myeloid progenitor cells) in patients with various leukemias after chemotherapy…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer [NA]
This terminated clinical trial evaluated a conditioning regimen of fludarabine, cyclophosphamide, and total-body irradiation followed by cyc…
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: A Study of NeoRecormon (Epoetin Beta), CellCept (Mycophenolate Mofetil) and Prednisone in Patients With Low or Intermediate Myelodysplastic Syndromes. [Phase 2]
Phase 2 clinical trial update evaluating a combination of NeoRecormon (epoetin beta), CellCept (mycophenolate mofetil), and prednisone in pa…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Does Maitake Mushroom Extract Enhance Hematopoiesis in Myelodysplastic Patients? [Phase 2]
Phase 2 trial evaluating whether maitake mushroom extract can enhance hematopoiesis in patients with myelodysplastic syndromes; results have…