Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors [Phase 2]
Phase 2 clinical trial evaluating the combination of plerixafor and GM-CSF (sargramostim) for mobilizing hematopoietic stem cells from allog…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Study to Determine the Safety and Preliminary Efficacy of CC-1088 in the Treatment of Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial investigating CC-1088 for myelodysplastic syndromes has completed, reporting safety and preliminary efficacy results.
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating MS-275 (entinostat) in combination with GM-CSF in adults with myelodysplastic syndromes and/or relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay [NA]
Clinical trial update on using a high-throughput drug sensitivity assay to guide treatment for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant [Phase 1]
A Phase 1 trial evaluating rasburicase to prevent graft-versus-host disease in patients undergoing donor stem cell transplantation; the stud…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders [Phase 2]
Phase 2 clinical trial evaluating nonmyeloablative allogeneic stem cell transplantation for various hematologic disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy [Phase 1]
This Phase 1 trial update reports on transplantation using specially treated bone marrow for hematologic cancers that have not responded to …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Long Term Safety Study of SyB L-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS) - Extension Study [Phase 1]
Long-term safety results from a Phase 1 extension study of SyB L-1101 in patients with recurrent/relapsed or refractory myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Decitabine Followed by Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory AML and MDS [Phase 2]
Phase 2 clinical trial evaluated a sequence of decitabine followed by idarubicin and cytarabine in adults with relapsed or refractory acute …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [NA]
A terminated clinical trial evaluated mobilizing donor peripheral blood stem cells with plerixafor and filgrastim before donor transplant in…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies [Phase 1]
Phase 1 clinical trial update describing safety assessments for two infusion schedules of SNS-595 in patients with hematologic malignancies.…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports completion of a study evaluating an investigational biological therapy in adults with advanced mye…
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating donor stem cell transplantation for patients with relapsed hematologic malignancies or secondary myelodysplasia who…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) in Combination With Azacitidine for the Treatment of Myelodysplastic Syndrome (MDS) [Phase 1]
A Phase 1 trial evaluating the combination of plerixafor and G-CSF with azacitidine for myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899) [Phase 3]
This Phase 3 trial comparing posaconazole prophylaxis against standard azole therapy in neutropenic patients has completed. It includes pati…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-thalassaemia Patients) With Chronic Iron Overload [Phase 4]
Phase 4 trial assessing the efficacy of Deferasirox for iron chelation in transfusion-dependent chronic anemia due to myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload [Phase 4]
Novartis-sponsored Phase 4 trial assessing heart and liver iron load by MRI in patients with transfusion-related iron overload; the study st…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia [Phase 1]
Phase 1 trial evaluating low-dose total-body irradiation and fludarabine phosphate followed by an unrelated donor stem cell transplant in pa…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Tosedostat in Combination With Cytarabine or Decitabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating the combination of tosedostat with cytarabine or decitabine in adults with newly diagnosed acute myeloid leukemia o…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Therapeutic Allogeneic Lymphocytes and Aldesleukin in Treating Patients With High-Risk or Recurrent Myeloid Leukemia After Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating therapeutic allogeneic lymphocytes with aldesleukin for high-risk or recur…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Autologous Cytokine-induced Killer Cell Adoptive Immunotherapy for Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous cytokine-induced killer cell adoptive immunotherapy for acute myeloid leukemia and myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Efficacy and Safety of Ultra Small Dose Decitabine for the Lower Risk MDS Patients With Transfusion Dependent [Phase 2]
This Phase 2 clinical trial update evaluates the efficacy and safety of ultra-small-dose decitabine in lower-risk, transfusion-dependent mye…
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia [Phase 1]
Phase 1 pilot trial of lenalidomide in adult Diamond-Blackfan anemia patients with transfusion-dependent anemia. The study was terminated an…
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Phase II Study to Evaluate Overall Response in Patients With Higher Risk Myelodysplastic Syndromes (MDS) Treated With Azacitidine With or Without Deferasirox. [Phase 2]
A Phase II trial in higher-risk myelodysplastic syndromes evaluating azacitidine with or without deferasirox has been terminated; results ha…
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome [NA]
This clinical trial update indicates the Lactobacillus probiotic study intended to prevent infection in patients undergoing donor stem cell …