Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2) [Phase 1, Phase 2]
This clinical trial update reports the completion and posted results of Phase 1 and Phase 2 studies of PKC412 (midostaurin) in adults with a…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen [Phase 1, Phase 2]
A Phase 1/2 trial evaluating allogeneic hematopoietic cell transplantation using a busulfan-based conditioning regimen across multiple hemat…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating busulfan, fludarabine, and total-body irradiation as conditioning for donor stem cell transplantation …
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemia [Phase 2]
Phase 2 results update for Vosaroxin (Voreloxin) in older patients with untreated acute myeloid leukemia; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant [Phase 2]
This Phase 2 trial evaluated sirolimus, tacrolimus, and antithymocyte globulin to prevent graft-versus-host disease in patients with hematol…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Study of 72-Hour Infusion of ON 01910.Na in Patients With MDS or AML [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a 72-hour infusion of ON 01910.Na in patients with myelodysplastic syndromes or acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematological Cancer or Other Disease [Phase 2]
Phase 2 trial update describing donor umbilical cord blood transplantation for advanced hematologic cancers, including leukemia, lymphoma, m…
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDS [Phase 2]
Phase 2 efficacy study evaluating lenalidomide (Revlimid) with low-dose continuous melphalan for high-risk myelodysplastic syndromes, includ…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Idarubicin Combined to Azacitidine in Int-2 or High Risk Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 study evaluating the combination of idarubicin and azacitidine in patients with intermediate-2 or high-risk myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 study evaluating plerixafor (AMD3100) as a stem cell mobilizer for transplantation from a sibling donor in various hematologic mal…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Low-dose Oral Clofarabine for the Treatment of IPSS INT-1, INT-2 or HIGH Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
This terminated Phase 1/2 trial evaluated low-dose oral clofarabine for IPSS INT-1/INT-2 or high-risk myelodysplastic syndromes and chronic …
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron Overload [Phase 4]
Phase 4 trial assessing the efficacy and safety of deferasirox in patients with myelodysplastic syndrome and transfusion-dependent iron over…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Azacitidine and Erythropoietin Versus Azacitidine Alone for Patients With Low-Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 trial comparing azacitidine plus erythropoietin versus azacitidine alone in low-risk myelodysplastic syndromes; study terminated wit…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning with busulfan and fludarabine, with or without antithymocyte globulin, followed by d…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: T-Cell Depletion, Donor Hematopoietic Stem Cell Transplant (HSCT), and T-Cell Infusions in Treating Patients With Hematologic Cancer or Other Diseases [Phase 2]
Phase 2 study evaluating T-cell depletion and donor hematopoietic stem cell transplantation with T-cell infusions in patients with various h…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer [Phase 2]
Phase 2 trial evaluating a conditioning regimen with alemtuzumab, fludarabine phosphate, and total-body irradiation followed by cyclosporine…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases [NA]
This ClinicalTrials.gov update reports on a completed study evaluating whether music can reduce anxiety and pain in adults undergoing bone m…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Azacitidine in Treating Patients With Relapsed Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant [Phase 2]
Phase 2 trial of azacitidine in patients with relapsed myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Alemtuzumab, Busulfan, and Cyclophosphamide Followed By a Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating conditioning with alemtuzumab, busulfan, and cyclophosphamide followed by donor stem cell transplantatio…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Azacitidine and Etanercept in Treating Patients With Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports results for the combination of azacitidine and etanercept in patients with myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases [Phase 2]
Phase 2 trial evaluating donor peripheral stem cell transplant and donor natural killer cell transplant after conditioning with total-body i…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating cyclophosphamide as GVHD prophylaxis after allogeneic peripheral blood stem cell transplantation in patients with h…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases [Phase 3]
Phase 3 trial evaluating donor bone marrow transplant with or without G-CSF in young patients with hematologic cancers or related diseases; …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant [Phase 3]
A Phase 3 trial of moxifloxacin to prevent bacterial infections in patients who have undergone a donor stem cell transplant was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Donor Peripheral Stem Cell Transplant, Fludarabine, and Busulfan in Treating Patients With Hematologic Cancers [Phase 2]
Phase 2 trial assessing donor peripheral stem cell transplant with fludarabine and busulfan in hematologic cancers has completed; results po…