Myelodysplastic Syndromes
📧 Sign up to get email alerts when something new happens for Myelodysplastic Syndromes.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2019-02-27Clinical Trial Update: The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality [Phase 2]
Phase 2 trial evaluating lenalidomide monotherapy in red blood cell transfusion dependent MDS with del(5q) shows efficacy and safety data.
-
CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMML [Phase 1]
Phase I dose-escalation study of volasertib in combination with azacitidine in patients with myelodysplastic syndromes or chronic myelomonoc…
-
CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Follow up Protocol to the Phase I/II Study of OPN-305 in Second-line or Third-line Lower Lower Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
Follow-up protocol for the Phase I/II study of OPN-305 in second- or third-line lower-risk myelodysplastic syndrome; the trial status is com…
-
CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: A Phase I/II Study of OPN-305 in Second-line Lower Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
This document reports the completion of a Phase I/II trial evaluating OPN-305 in second-line lower-risk myelodysplastic syndromes.
-
CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203) [Phase 2]
Phase 2 study evaluating novel approaches to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation, with res…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Development of an in Vitro Hematopoietic Culture System and Application to Myelodysplastic Syndromes.
This document reports a completed clinical trial update on developing an in vitro hematopoietic culture system and its application to myelod…
-
CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial results update for Vyxeos (CPX-351) in relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes; results we…
-
CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 results from a study using donor umbilical cord blood stem cell transplants in patients with hematologic malignancies have been post…
-
CLINICAL_TRIALS trial_result · 2018-12-21Clinical Trial Update: Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS [Phase 1, Phase 2]
A phase 1/2 trial of Vadastuximab talirine in combination with azacitidine for previously untreated higher-risk myelodysplastic syndrome was…
-
CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS). [Phase 1, Phase 2]
Clinical trial update on safety of oral azacitidine (CC-486) as maintenance therapy after allogeneic stem cell transplantation in AML or MDS…
-
CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Myelodysplastic Syndromes [EARLY_Phase 1]
Early-phase clinical trial update on a vaccine therapy for myelodysplastic syndromes (Phase 1; terminated; results posted).
-
CLINICAL_TRIALS trial_result · 2018-11-15Clinical Trial Update: Phase I/II Study of Decitabine and Valproic Acid in Relapsed/Refractory Leukemia or Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase I/II study evaluating decitabine and valproic acid in relapsed/refractory leukemia or myelodysplastic syndromes; study completed.
-
CLINICAL_TRIALS trial_result · 2018-11-15Clinical Trial Update: SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update examining SGI-110 with donor lymphocyte infusions after allogeneic stem cell transplantation for myelodysplast…
-
CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Amifostine in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating amifostine for treating myelodysplastic syndromes has completed.
-
CLINICAL_TRIALS trial_result · 2018-10-24Clinical Trial Update: Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders [Phase 2]
Phase 2 clinical trial evaluating fludarabine phosphate and total body irradiation followed by donor peripheral stem cell transplant in myel…
-
CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: A Phase I/II Study of Gene-modified WT1 TCR Therapy in MDS & AML Patients [Phase 1, Phase 2]
Phase I/II trial of gene-modified WT1 TCR therapy in patients with myelodysplastic syndromes and acute myeloid leukaemia has completed.
-
CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Genomic Predictors of Decitabine Response in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 2]
Phase 2 trial update evaluating genomic predictors of decitabine response in patients with acute myeloid leukemia or myelodysplastic syndrom…
-
CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: Experimental Bone Marrow Transplant Protocol [Phase 2]
Phase 2 clinical trial update for an experimental bone marrow transplant protocol that investigated treatment in blood cancer conditions; st…
-
CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 pilot study evaluating alemtuzumab (Campath) in patients with myelodysplastic syndromes has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Lenalidomide and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating lenalidomide in combination with azacitidine for advanced myelodysplastic syndromes has completed with…
-
CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Phase 1/2 Study of the ERK1/2 Inhibitor BVD-523 in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 study evaluating the ERK1/2 inhibitor BVD-523 (ulixertinib) in patients with acute myeloid leukemia or myelodysplastic syndromes; …
-
CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Bexarotene and GM-CSF in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 2]
A phase 2 clinical trial evaluating the combination of bexarotene and GM-CSF in patients with myelodysplastic syndromes or acute myeloid leu…
-
CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: HLA 10/10 Matched Unrelated Donor vs Haploidentical Allogenic Hematopoietic Stem Cell Transplantation [Phase 3]
Phase 3 trial comparing HLA 10/10 matched unrelated donor versus haploidentical allogeneic hematopoietic stem cell transplantation for acute…
-
CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Combination Chemotherapy, Bone Marrow Transplant, and Post Transplant Cyclophosphamide for Hematologic Cancer [Phase 2]
Phase 2 trial update on a combination chemotherapy, bone marrow transplant, and post-transplant cyclophosphamide regimen for hematologic can…
-
CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Cholecalciferol in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating cholecalciferol (vitamin D3) for treating patients with myelodysplastic syndromes, completed.