Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies [Phase 1]
This is a Phase 1, multi-institutional trial evaluating expanded multi-antigen oriented lymphocytes for very high-risk hematologic malignanc…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform
Describes a global Shwachman-Diamond Syndrome patient survey and partnering platform sponsored by the Shwachman-Diamond Syndrome Alliance, I…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Study of 3D189 in Patients With Hematologic Malignancies [Phase 1]
Phase 1 study of 3D189 in hematologic malignancies is active but not recruiting.
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002) [Phase 1]
An early-phase clinical trial evaluating Tagraxofusp as post-transplant maintenance in patients with CD123-positive acute myeloid leukemia, …
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 study evaluating LYT-200 in adults with relapsed/refractory acute myeloid leukemia or relapsed/refractory high-risk myelodysplastic …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML [Phase 1, Phase 2]
Clinical trial update showing CFI-400945 with or without azacitidine is being studied in acute myeloid leukemia, myelodysplastic syndromes, …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Molecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial investigating molecular genetics-guided maintenance therapy after allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: A Study to Evaluate Treatment Patterns and Effectiveness of Luspatercept
A clinical trial update assessing treatment patterns and the effectiveness of luspatercept in myelodysplastic syndromes; the study is curren…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Registry of Myelodysplastic Syndromes and Therapy-related Acute Myeloid Leukemia
A new clinical trial registry entry for patients with myelodysplastic syndromes and acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children [Phase 2]
This clinical trial update describes a Phase 2 study evaluating KIR-favorable mismatched haploidentical transplantation and KIR polymorphism…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
Phase 1 study update for Orca-T in recipients undergoing allogeneic transplantation for hematologic malignancies; the trial is currently act…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Unified platforM for a Better integRal Evaluation of MyeLodyspLastic Syndromes in SpAin-Strategy for Unraveling Personalized genoMic Medicine in Public heAlth System (UMBRELLA-SUMMA)
A clinical trial update describing the Unified platform for a better integral evaluation of Myelodysplastic Syndromes in Spain (UMBRELLA-SUM…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS (ACROBAT) [Phase 3]
A Phase 3 clinical trial (ACROBAT) investigates the feasibility of allogeneic stem cell transplantation in patients with higher-risk myelody…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Total Body Irradiation and Cladribine Before Allogeneic Hematopoietic Cell Transplantation in Patients With AML (Acute Myeloid Leukemia) and Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial is evaluating total body irradiation and cladribine as conditioning before allogeneic hematopoietic cell transplant…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Study of REM-422 in Patients With AML or Higher Risk MDS [Phase 1]
Remix Therapeutics is conducting a Phase 1 study of REM-422 in patients with myelodysplastic syndromes and acute myeloid leukemia, including…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia [Phase 2]
This entry describes a Phase 2 clinical trial evaluating matched unrelated donor versus haploidentical donor approaches for allogeneic stem …
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: 5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies [EARLY_Phase 1]
Early-phase clinical trial evaluating epigenetic therapy with azacitidine and decitabine for myeloid malignancies; the study is currently re…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML [Phase 2]
Phase 2 clinical trial evaluating salvage therapy with venetoclax and decitabine for relapsed/refractory acute myeloid leukemia. The study a…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating hyperbaric oxygen therapy in combination with allogeneic peripheral blood stem cell transplant…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia [Phase 1]
A Phase 1 study of eltanexor with venetoclax for relapsed or refractory myelodysplastic syndromes and acute myeloid leukemia is currently re…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical Transplantation [Phase 2]
Phase 2 clinical trial evaluating an anti-NKG2A monoclonal antibody in Acute Myeloid Leukemia or Myelodysplastic Syndromes patients undergoi…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia [Phase 3]
A Phase 3 trial comparing oral decitabine/cedazuridine with azacitidine in myelodysplastic syndromes, acute myeloid leukemia with low blast …
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Involvement of CDA and/or dCK Metabolizing Enzymes in the Response to Azacytidine Treatment of Patients With Hematologic Malignancies [NA]
A clinical trial update examining whether CDA and/or dCK metabolizing enzymes influence the response to azacitidine in patients with hematol…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Phase 1 Trial of ASTX727 in Subjects With Lower-risk Myelodysplastic Syndromes [Phase 1]
Phase 1 trial update for ASTX727 in lower-risk myelodysplastic syndromes indicates the study is currently active but not recruiting.