Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS) [Phase 1]
Phase 1 clinical trial evaluating venetoclax in combination with azacitidine in treatment-naïve, higher-risk myelodysplastic syndromes is on…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies
This study evaluates frailty phenotype assessments to optimize treatment strategies for older patients with hematologic malignancies. It is …
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Oral Arsenic (ATO) in Low-risk Myelodysplastic Syndromes (MDS) [Phase 1]
A Phase 1 clinical trial evaluating oral arsenic (arsenic trioxide) for low-risk myelodysplastic syndromes is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT) [NA]
Clinical trial update for ACT evaluating compassionate communication and advance care planning to improve end-of-life care in hematologic di…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Assesment of the Immune Response to RSV Vaccine in Patients With Myeloma, Lymphoma and Hematological Leukemia
This clinical trial update assesses the immune response to an RSV vaccine in patients with hematologic cancers, including multiple myeloma, …
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Reduced ATG Plus Mini PTCy for GVHD Prophylaxis in Haplo-SCT [Phase 2]
Phase 2 trial evaluating reduced ATG plus mini post-transplant cyclophosphamide for graft-versus-host disease prophylaxis in haploidentical …
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant [NA]
This study update notes that a trial investigating cognitive outcomes in older adults receiving stem cell transplant is currently in RECRUIT…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Mosaic Trial for Stem Cell Transplant Recipients [NA]
This clinical trial update indicates the Mosaic trial for stem cell transplant recipients is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study
A feasibility pilot study evaluating the use of the OURA Ring wearable in patients with myelodysplastic syndromes to explore discovery endpo…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
This clinical trial update describes the use of the PET imaging agent 18F-fluorothymidine (18F-FLT) in cancer patients to assess tumor proli…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: A Randomized Phase II Study of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplant [Phase 2]
A Phase II randomized trial evaluating hyperbaric oxygen to improve engraftment after umbilical cord blood stem cell transplantation in pati…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Eltrombopag as a Novel Therapeutic Approach for Low-risk MDS and CMML With TET2 Mutations [Phase 2]
Phase 2 clinical trial evaluating eltrombopag as a treatment for low-risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia with…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation [Phase 2]
Phase 2 trial evaluating maintenance therapy with ivosidenib after allogeneic stem cell transplantation in patients with acute myeloid leuke…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of combining hydroxyurea with valproic acid or 6-mercaptopurine with valproic acid in…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML [Phase 1]
Phase 1 clinical trial update for GTB-3650 Trike in high-risk myeloid malignancies, including acute myeloid leukemia and myelodysplastic syn…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of oral LY3410738 in patients with IDH1/IDH2-mutant hematologic malignancies is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 clinical trial evaluating intensity-modulated total marrow irradiation in fully matched and partially matched allogeneic transplan…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Registry of Older Patients With Cancer
This clinical trial registry entry from UNC Lineberger indicates an ongoing recruitment for a registry of older patients with cancer, includ…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Collection of Samples of Bone Marrow Aspiration From Patients With Myelodysplastic Syndrome
A clinical trial by Minovia Therapeutics collecting bone marrow aspiration samples from patients with myelodysplastic syndromes; the study s…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy
This document outlines a clinical trial protocol to genomically profile, collect, archive, and distribute blood and bone marrow specimens fr…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Comparison of ATLG and ATG for Immune Reconstitution After Allo-HSCT for Hematologic Malignancy
Clinical trial comparing ATLG versus ATG for immune reconstitution after allogeneic hematopoietic stem cell transplantation in hematologic m…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Oral-ATO for TP53-mutated Myeloid Malignancies [Phase 2]
A Phase 2 clinical trial evaluating oral arsenic trioxide for TP53-mutated myeloid malignancies, including acute myeloid leukemia and myelod…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation [Phase 1]
This Phase 1 trial update discusses orally administered AG-120 (ivosidenib) for IDH1-mutated hematologic malignancies, including relapsed/re…