Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Home Blood Transfusions [NA]
Thomas Jefferson University is recruiting for a clinical trial on home blood transfusions. The study targets patients with hematologic malig…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants
Clinical trial sponsored by the National Cancer Institute studying individuals and families with DDX41 or similar cancer predisposition vari…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS [NA]
A clinical trial evaluating whole genome sequencing (ChromoSeq) as an adjunct to conventional genomic profiling in myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms [Phase 2]
Phase 2 study evaluating luspatercept for anemia in patients with lower-risk myelodysplastic syndromes or non-proliferative myeloproliferati…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
An ongoing clinical trial investigating muscle dysfunction in patients with hematologic diseases referred for stem cell transplantation.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors [Phase 2]
Phase 2 study evaluating exercise training with nicotinamide riboside (NR) supplementation to improve fitness in adolescent/young adult hema…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Expanded Natural Killer Cells Following Haploidentical HSCT for AML/MDS [Phase 1, Phase 2]
Clinical trial investigating expanded natural killer cells after haploidentical hematopoietic stem cell transplantation for acute myeloid le…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Venetoclax-containing Therapy Combined With Microtransplant for Intermediate-risk and Higher MDS [Phase 2]
A Phase 2 clinical trial is investigating a Venetoclax-containing regimen with microtransplant for patients with intermediate-risk or higher…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4). [Phase 3]
A Phase 3 clinical trial (GLORA-4) is evaluating lisaftoclax (APG-2575) in combination with azacitidine for higher-risk myelodysplastic synd…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched Donor [Phase 2]
Phase 2 clinical trial update evaluating post-transplantation benadamustine and cyclophosphamide in high-risk myeloid malignancies with part…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials [Phase 3]
This clinical trial update describes a Phase 3 study evaluating the long-term safety of luspatercept in participants who have previously par…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML [Phase 1]
Phase 1 clinical trial evaluating danvatirsen as monotherapy followed by combination with venetoclax in relapsed/refractory myelodysplastic …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: A Study to Assess Luspatercept in Lower-risk Myelodysplastic Syndrome Participants [Phase 3]
Clinical trial update for a Phase 3 study of luspatercept in lower-risk myelodysplastic syndrome; the study is currently active but not recr…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Investigation of the Genetics of Hematologic Diseases
A St. Jude-sponsored clinical trial update indicates a study on the genetics of hematologic diseases is currently recruiting, covering sever…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose) [Phase 2]
Phase 2 study update for participants who previously took ASTX727 (oral decitabine/cedazuridine) that is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating allogeneic stem cell transplantation with alpha/beta T and B cell depletion for hematologic malignancies; …
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Canakinumab With Darbepoetin Alfa in PTs With Lower-Risk MDS Who Have Failed ESA [Phase 1, Phase 2]
This Phase 1/Phase 2 clinical trial is evaluating the combination of canakinumab and darbepoetin alfa in patients with lower-risk myelodyspl…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: UM171 Expanded Cord Blood In Patients With High-Risk Acute Leukemia/Myelodysplasia [Phase 2]
Phase 2 clinical trial update for UM171 expanding cord blood in patients with high-risk acute leukemia or myelodysplastic syndromes. The stu…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
This ClinicalTrials.gov update describes an ongoing study that collects tissue, blood, and body fluid samples from patients with hematologic…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India [Phase 4]
Phase 4 clinical trial evaluating the safety and effectiveness of luspatercept for transfusion-dependent anemia associated with myelodysplas…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: IS-free Treg HaploHCT [Phase 1]
A Phase 1 clinical trial at Dana-Farber Cancer Institute evaluating an IS-free regulatory T cell haploidentical hematopoietic cell transplan…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS [NA]
Clinical trial investigating whole genome sequencing (ChromoSeq) as an adjunct to conventional genomic profiling in acute myeloid leukemia a…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating interferon-γ in combination with donor leukocyte infusion for relapsed acute myeloid leukemia and myelodys…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Umbilical Cord Blood Transplantation From Unrelated Donors
This is an ongoing clinical trial evaluating umbilical cord blood transplantation from unrelated donors for hematologic diseases. The study …
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial from University of Alabama at Birmingham evaluating a two-step anti-thymocyte globulin regimen to prevent acute gra…