Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS [Phase 1]
Phase 1 study evaluating APL-4098 alone and in combination for adults with acute myeloid leukemia or myelodysplastic syndromes; currently re…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Defining Inflammatory Markers of Cardiovascular Disease in Patients With Myelodysplastic Syndromes
A clinical trial sponsored by the University of Vermont is recruiting to study inflammatory markers associated with cardiovascular disease i…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: The National Myelodysplastic Syndromes (MDS) Study
The NHLBI-sponsored National Myelodysplastic Syndromes study (NCT02775383) has completed.
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis [NA]
This clinical trial is investigating anti-platelet antibodies detected with the MAIPA assay to demonstrate the autoimmune nature of thromboc…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: PK/Efficacy Bridging Study of ASTX727 in Chinese Subjects With Myelodysplastic Syndromes [Phase 1, Phase 2]
This is a Phase 1/2 PK and efficacy bridging study of ASTX727 in Chinese patients with myelodysplastic syndromes, sponsored by Otsuka Beijin…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT [Phase 1]
A Phase I clinical trial for patients with advanced hematologic malignancies undergoing allogeneic hematopoietic cell transplantation is cur…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders [Phase 2]
Phase 2 clinical trial update investigating alpha/beta T cell receptor alpha/beta-depleted hematopoietic cell transplantation in inherited b…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms [Phase 1]
Phase 1 clinical trial evaluating a triple combination of navitoclax, venetoclax, and decitabine for advanced myeloid neoplasms. The study i…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Romiplostim N01 for Platelet Recovery After Haploidentical HSCT [Phase 1]
Phase 1 clinical trial evaluating Romiplostim N01 for platelet recovery after haploidentical hematopoietic stem cell transplantation. The st…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating induction and consolidation with fludarabine, cytarabine, idarubicin, and venetoclax for acute myeloid leu…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS) [Phase 1]
A Phase 1 study evaluating an oral tetrahydrouridine-decitabine combination for relapsed or refractory myelodysplastic syndromes is currentl…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes [Phase 2]
This is a Phase 2 study evaluating intensity-modulated total marrow irradiation added to fludarabine/busulfan conditioning for allogeneic tr…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1]
MacroGenics reports a Phase 1 study of MGD024 in relapsed or refractory hematologic malignancies is currently recruiting across multiple dis…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating the combination of venetoclax and azacitidine for relapsed or refrac…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS [Phase 1]
Phase 1 clinical trial evaluating Venetoclax in combination with intensive chemotherapy for acute myeloid leukemia and advanced myelodysplas…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab. [Phase 2]
A Phase 2 rollover study from Novartis continues Sabatolimab (MBG453) treatment for patients who completed a prior study, to assess continue…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: A Study of TAK-226 for Transfusion-Dependent Anemia in Japanese Patients With Lower-Risk Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial evaluating TAK-226 for transfusion-dependent anemia in Japanese patients with lower-risk myelodysplastic syndromes …
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT [NA]
This clinical trial (NCT07319793) sponsored by Peking University People's Hospital is evaluating pre-DLI or pro-DLI approaches in relapsed o…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
A registry-based study (Biology and Outcome Project) enrolling patients with acute myeloid leukemia and myelodysplastic syndromes/AML to cha…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation [Phase 1]
Phase 1 clinical trial evaluating preemptive CIML NK cell therapy after hematopoietic stem cell transplantation in patients with acute myelo…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts [Phase 2]
A Phase II trial is evaluating a combination regimen of cladribine and low-dose cytarabine with venetoclax, alternating with azacitidine and…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Follow-up Study of ICUS and CCUS Patients
This document provides an update on a follow-up clinical study of ICUS and CCUS patients with myelodysplastic syndromes, including enrollmen…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation [Phase 2]
A Phase 2 dose-expansion study evaluating a low-dose post-transplant cyclophosphamide/tacrolimus/ruxolitinib regimen for graft-versus-host d…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome [Phase 1]
A Phase 1 clinical trial update evaluating SX-682 alone and in combination with decitabine in patients with myelodysplastic syndromes. The s…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research Study
A clinical trial update describing a secondary research study that analyzes molecular and clinical aspects of bone marrow failure and VEXAS …