Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients
An ongoing clinical trial from the Weizmann Institute of Science is evaluating whether peripheral blood analysis can replace bone marrow dia…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes [Phase 1]
Phase 1 safety and proof-of-concept study of the experimental drug RPT1G in adults with acute myeloid leukemia and high-risk myelodysplastic…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide [Phase 1]
Phase 1 clinical trial update evaluating expanded/activated gamma delta T-cell infusion after hematopoietic stem cell transplantation with p…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions [Phase 3]
Phase 3 study ELEMENT-MDS evaluating the efficacy and safety of Luspatercept in participants with Myelodysplastic Syndromes and anemia not r…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Pre-emptive Therapy With DEC-C to Improve Outcomes in MDS Patients With Measurable Residual Disease Post Allogeneic Hematopoietic Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pre-emptive DEC-C therapy to improve outcomes in myelodysplastic syndrome patients with measurable res…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Clonal Hematopoiesis of Immunological Significance
This is a clinical trial update about clonal hematopoiesis of immunological significance (CHIS) sponsored by Assistance Publique - Hôpitaux …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies [Phase 2]
Phase 2 pilot study to assess feasibility of using decitabine with filgrastim as post-transplant prophylaxis in children and young adults wi…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS [Phase 1]
Phase 1 clinical trial evaluating a combination of epigenetic therapy and sensitising therapy in acute myeloid leukemia, myelodysplastic syn…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Fludarabine Plus Melphalan Versus Addition of Venetoclax to Fludarabine/Melphalan Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in AML/MDS Patients Aged > 50 Years: a Multicenter, Randomized, Phase 3 Trial [Phase 3]
A Phase 3 randomized trial assessing whether adding venetoclax to the fludarabine/melphalan conditioning regimen improves outcomes for adult…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Pacritinib With Aza for Upfront Myelodysplastic Syndrome [Phase 1, Phase 2]
An ongoing Phase 1/2 trial is evaluating pacritinib in combination with azacitidine for upfront treatment of myelodysplastic syndromes; the …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Ascorbate in Myelodysplastic Syndrome [Phase 2]
A Phase 2 clinical trial evaluating ascorbate for myelodysplastic syndromes is currently recruiting. The study details are listed on Clinica…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Phase Ib Study of CD33 FPBMC in Patients With MRD+ AML or MDS [Phase 1]
This clinical trial update notes a Phase 1 study of CD33 FPBMC in patients with measurable residual disease positive acute myeloid leukemia …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Oral Azacitidine Combined With Venetoclax in Previously Untreated Higher-risk Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating oral azacitidine combined with venetoclax in previously untreated higher-risk myelodysplastic syndr…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Venetoclax Basket Trial for High Risk Hematologic Malignancies [Phase 1]
A Phase 1 Venetoclax basket trial across multiple high-risk hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Venetoclax in Patients With MDS or AML in Relapse After AHSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating venetoclax in patients with myelodysplastic syndromes or acute myeloid leukemia relapsing after all…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases [NA]
This entry reports an ongoing clinical trial evaluating myeloablative preparative regimens for umbilical cord blood transplantation across s…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study of Incidence, Treatment Patterns, and Outcomes in Transfusion-dependent Lower-risk Myelodysplastic Syndromes in Spain
An observational clinical study in Spain investigates incidence, treatment patterns, and outcomes in transfusion-dependent lower-risk myelod…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions [Phase 3]
Phase 3 trial evaluating elritercept to treat anemia in adults with very low to intermediate-risk myelodysplastic syndromes who require regu…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment [Phase 1]
Phase 1 study evaluating the pharmacokinetics and safety of the oral decitabine and cedazuridine combination in cancer patients with renal i…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment [Phase 1]
A phase 1 trial is evaluating the pharmacokinetics and safety of orally administered decitabine in combination with cedazuridine in cancer p…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions [Phase 3]
A Phase 3 clinical trial compares elritercept with epoetin alfa to treat anemia in adults with very low-, low-, or intermediate-risk myelody…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia [Phase 1, Phase 2]
Ongoing Phase 1/2 study of DISC-0974 (RALLY-MF) in patients with myelofibrosis and anemia; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Study of an Innovative Therapy Using CAR-T Cells Targeting IL-1RAP in Patients With High-Risk Myelodysplastic Syndromes (MDS [NA]
A clinical study is evaluating an innovative CAR-T cell therapy that targets IL-1RAP in patients with high-risk myelodysplastic syndromes; t…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Nivolumab and/or Ipilimumab With or Without Azacitidine in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating nivolumab and/or ipilimumab with or without azacitidine for myelodysplastic syndromes; currently active but not rec…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory [Phase 1]
A Phase 1 clinical trial evaluating pembrolizumab plus decitabine, with or without venetoclax, for patients with acute myeloid leukemia or m…