Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Study of HS-20106 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial evaluating HS-20106 for anemia due to very low, low, or intermediate-risk myelodysplastic syndromes. The study status…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: TMLI Plus Chemotherapy in High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial evaluating total marrow and lymphoid irradiation (TMLI) with chemotherapy for high-risk myelodysplastic syndromes a…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: TMLI/Fludarabine/Melphalan Conditioning for Allogeneic Transplantation in High-risk Myelodysplastic Syndrome or Acute Myeloid Leukemia. [Phase 2]
Phase 2 clinical trial evaluating total marrow irradiation-based conditioning with fludarabine and melphalan for allogeneic transplantation …
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation [NA]
This ClinicalTrials.gov update reports a completed feasibility study evaluating an adapted physical activity program for children, adolescen…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: A Clinical Trial of TQB3455 Tablets in Patients With Hematological Malignancies [Phase 1]
Phase 1 clinical trial of TQB3455 tablets for hematological malignancies is currently recruiting in patients with acute myeloid leukemia and…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: VA Combined With PD-1 Inhibitor for the Treatment of Relapsed and Refractory AML and High-risk MDS [Phase 2]
A Phase 2 clinical trial is evaluating the combination of a VA agent with a PD-1 inhibitor for relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen [Phase 2]
Phase 2 clinical trial evaluating sorafenib as relapse prophylaxis after hematopoietic cell transplantation using the PTBCy regimen; the stu…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes
This clinical trial update describes ongoing efforts to collect and store blood, bone marrow, and other samples from patients with acute leu…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement
This clinical trial is testing an intensive conditioning regimen consisting of Thiotepa, Busulfan, Fludarabine, and Cytarabine followed by a…
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Immunophenotyping of Blood Cells in the Diagnosis Work-up of Myelodysplastic Syndromes
A clinical trial is evaluating immunophenotyping of blood cells to assist in the diagnostic work-up of myelodysplastic syndromes and is curr…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AML [Phase 1]
Clinical trial update for ACHIEVE2 reports safety and preliminary efficacy data for intravenous TCB008 in patients with relapse or refractor…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT [Phase 3]
Phase 3 randomized trial evaluating oral azacitidine versus placebo as maintenance therapy after allogeneic stem cell transplantation in pat…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessing adding venetoclax to FLAMSA/treosulfan conditioning for allogeneic stem cell transplantation in patient…
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CLINICAL_TRIALS research · 2023-07-14Clinical Trial Update: Validation of a Predictive Model of Response to Romiplostim in Patients With IPSS Low or Intermediate-1 Risk MDS and Thrombocytopenia [Phase 2]
A Phase 2 clinical trial evaluating a predictive model for response to Romiplostim in patients with IPSS low or intermediate-1 risk myelodys…
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CLINICAL_TRIALS research · 2022-07-12Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following Partially Mismatched Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating gene-modified donor T-cells after partially mismatched stem cell transplantation in patients with leukem…
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CLINICAL_TRIALS research · 2019-02-19Clinical Trial Update: Best Promising Drug Association With Azacitidine in Higher Risk Myelodysplastic Syndromes [Phase 2]
An update on a Phase 2 trial investigating azacitidine-based therapy for higher-risk myelodysplastic syndromes. The current status of the st…
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers [Phase 2]
This clinical trial update describes a Phase 2 study evaluating donor lymphocyte infusion after stem cell transplant for hematologic cancers…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Chidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCT [Phase 2]
Phase 2 clinical trial evaluating chidamide plus post-transplant cyclophosphamide and cyclosporine to prevent graft-versus-host disease afte…
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: AVIDA The Vidaza® (Azacitidine) Patient Registry
This update concerns the AVIDA Vidaza (azacitidine) patient registry for myelodysplastic syndromes, noting that the registry study has compl…
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CLINICAL_TRIALS research · 2018-04-26Clinical Trial Update: Red Blood Cell Transfusion Thresholds and QOL in MDS [NA]
Clinical trial update examining red blood cell transfusion thresholds and quality of life in patients with myelodysplastic syndromes.
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS research · 2017-11-08Clinical Trial Update: Myelodysplastic Syndrome--CDA-2 Hematological Improvement National Affirmation Study [Phase 4]
This is a Phase 4 clinical trial update for Myelodysplastic Syndromes evaluating CDA-2 hematologic improvement in a national study. The stat…
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CLINICAL_TRIALS research · 2017-11-08Clinical Trial Update: A Clinical Trial Evaluating the Efficacy of Ultra Low Dose of Decitabine in Myelodysplastic Syndromes (MDS) [NA]
A clinical trial is evaluating the efficacy of ultra-low-dose decitabine in myelodysplastic syndromes, with no current status reported.
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CLINICAL_TRIALS research · 2017-04-13Clinical Trial Update: B7.1/IL-2 Leukaemia Cell Vaccine for Non-Transplant AML RFUSIN2-AML2 (NTX) [Phase 1]
Phase 1 clinical trial update of a B7.1/IL-2 leukemia cell vaccine for non-transplant acute myeloid leukemia and myelodysplastic syndromes; …