Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Selinexor Combined With Venetoclax Maintenance Therapy After Allo-HSCT [Phase 2]
Phase 2 clinical trial update evaluating the combination of selinexor and venetoclax as maintenance therapy after allogeneic hematopoietic s…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant with Dilanubicel for HIV-positive hematologic cancers; the study was terminated and results w…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: A Phase 1 Study of FD-001 in Recurrent /Refractory (R/R)AML/NHL/MM/MDS [Phase 1]
A Phase 1 study of FD-001 in recurrent/refractory acute myeloid leukemia, non-Hodgkin lymphoma, multiple myeloma, and myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Biomarker-Directed Phase 2 Trial of Tamibarotene (SY-1425) in Participants With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
A biomarker-directed Phase 2 trial of tamibarotene (SY-1425) in acute myeloid leukemia and myelodysplastic syndrome has completed and posted…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) [Phase 2]
Phase 2 clinical trial update of flotetuzumab for relapsed acute myeloid leukemia and myelodysplastic syndrome after allogeneic stem cell tr…
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CLINICAL_TRIALS withdrawal · 2024-12-05Clinical Trial Update: A Study of FF-10501-01 in Combination with Azacitidine in Patients with Myelodysplastic Syndrome [Phase 2]
A Phase 2 study of FF-10501-01 in combination with azacitidine for myelodysplastic syndrome has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-12-05Clinical Trial Update: Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT [Phase 1]
A Phase 1 trial evaluating a preemptive infusion of donor lymphocytes depleted of TCR+ T cells and CD19+ B cells after autologous stem cell …
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS [Phase 2]
A Phase 2 clinical trial update investigating repurposing metformin as a leukemia-preventive drug for clonal hematopoiesis with CCUS and low…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Single Agent and Combined Inhibition After Allogeneic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating single-agent and combined inhibition after allogeneic stem cell transplant in patients with acute myeloid …
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies [Phase 1]
Phase 1 study of VIP943 in adults with advanced CD123+ hematologic malignancies is currently recruiting, including acute myeloid leukemia, B…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemia
A post-marketing surveillance study to assess the safety of luspatercept in Korean patients with myelodysplastic syndrome or beta-thalassemi…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial testing nivolumab and azacitidine with or without ipilimumab for refractory/relapsed or newly diagnosed acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update on a Triplex CMV vaccine designed to prevent CMV infection in patients undergoing hematopoietic stem cell tran…
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT) [Phase 2]
Phase 2 trial of a cytomegalovirus vaccine for donors and recipients undergoing allogeneic hematopoietic cell transplantation has completed,…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes? [NA]
Clinical trial in recruitment assessing whether exposure to O-type blood products affects patient outcomes in myelodysplastic syndrome. Spon…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Testing the Safety and Efficacy of the Combination of the Antibody Pembrolizumab and Entinostat in Patients With Myelodysplastic Syndrome Who Are Not Responding to Hypomethylating Agents [Phase 1]
Phase 1 results assess safety and preliminary efficacy of combining pembrolizumab with entinostat in patients with myelodysplastic syndrome …
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: VA as Maintenance Therapy Post Allo-HSCT in MDS and AML [Phase 2]
A Phase 2 trial evaluating VA as maintenance therapy after allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome a…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Magrolimab in Combination with Azacitidine After Allogeneic HCTin Treating Patients with High-Risk AML or MDS [Phase 1]
A Phase 1 trial of magrolimab in combination with azacitidine after allogeneic hematopoietic cell transplantation in high-risk acute myeloid…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Tolerability and Efficacy of Midostaurin to 10-day Decitabine in Unfit Adult AML and High Risk MDS Patients [Phase 2]
Phase 2 clinical trial evaluating tolerability and efficacy of adding midostaurin to a 10-day decitabine regimen in unfit adults with acute …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: IDH2-Post-Allo-Trial for Patients with IDH2-mut Myeloid Neoplasms After Allo-SCT [Phase 2]
This is a Phase 2 trial evaluating IDH2-mutant myeloid neoplasms after allogeneic stem cell transplantation. The study status is completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Clinical Registration Study of Haplo-HSCT for Elderly Patients With Acute Leukemia/ Myelodysplastic Syndrome
Registration study evaluating haploidentical hematopoietic stem cell transplantation for elderly patients with acute leukemia or myelodyspla…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: CPX-351 Therapy for MDS After Hypomethylating Agent Failure [Phase 2]
Phase 2 trial of CPX-351 for myelodysplastic syndrome after failure of hypomethylating agents was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Haploidentical Donor vs mMUD in Hematological Malignancies [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing haploidentical donor transplantation to matched unrelated donor transplantation in hematologic malignan…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Decitabine Versus Supportive Care in Adults With Advanced-stage MDS [Phase 3]
Phase 3 trial comparing decitabine to supportive care in adults with advanced-stage myelodysplastic syndrome has completed. The source notes…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden [Phase 3]
A Phase 3 trial evaluating Roxadustat for anemia in participants with lower-risk myelodysplastic syndrome and low red blood cell transfusion…