Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Efficacy and Safety of ON 01910.Na in Myelodysplastic Syndrome (MDS) Patients With Trisomy 8 or Classified as Intermediate-1, -2 or High Risk [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of ON 01910.Na in patients with myelodysplastic syndrome, including those with tri…
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CLINICAL_TRIALS trial_result · 2017-06-26Clinical Trial Update: Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating the efficacy and safety of oral rigosertib in transfusion-dependent myelodysplastic syndrome, including lower- and …
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Safety and Pharmacokinetic Study of Oral ON 01910.Na in Patients With Myelodysplastic Syndrome [Phase 1]
Phase 1 safety and pharmacokinetic study of ON-01910.Na (rigosertib) in patients with myelodysplastic syndrome has been completed, reporting…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Decitabine and Vorinostat Conditioning Followed by CD3-/CD19- NK Cells Infusion for High Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 trial evaluating decitabine and vorinostat conditioning followed by CD3-/CD19- NK cell infusion in high-risk myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and tolerability of HSC835 in patients with various hematologic malignancies completed with results posted …
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluated haploidentical allogeneic transplantation with post-transplant regulatory T-cell infusion in…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL) [Phase 2]
A phase 2 trial of alemtuzumab in myelodysplastic syndrome, aplastic anemia, and T-cell large granular lymphocytic leukemia was terminated, …
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FDA approval · 2017-05-03FDA Approved: DECITABINE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approves a supplemental ANDA for Dr. Reddy's Laboratories Inc. to market a generic decitabine product.
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission [Phase 2]
A Phase 2 trial evaluating conditioning with fludarabine and busulfan followed by allogeneic stem cell transplantation in older adults with …
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs [Phase 2]
A Phase 2 safety and tolerability trial evaluating CDX-301 with or without plerixafor for stem cell mobilization in matched related donor/re…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment [NA]
Clinical trial results posted on using hyperbaric oxygen therapy to improve umbilical cord blood stem cell homing and engraftment in patient…
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS) [Phase 2]
Phase II trial of a Hedgehog pathway inhibitor in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) completed with r…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders [Phase 2]
Phase 2 trial evaluating myeloablative conditioning with hyperfractionated total body irradiation plus thiotepa and fludarabine followed by …
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Arsenic Trioxide in Combination With Cytarabine in Patients With High-risk MDS and Poor-prognosis AML [Phase 1, Phase 2]
Phase 1/2 trial evaluating arsenic trioxide in combination with cytarabine for high-risk myelodysplastic syndrome and poor-prognosis acute m…
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FDA approval · 2017-02-27FDA Approved: DECITABINE — Original Application (Accord Healthcare Inc.)
FDA approves an original ANDA for decitabine by Accord Healthcare Inc., establishing a generic version of the drug.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Phase 2 Study Adding Pracinostat to a Hypomethylating Agent (HMA) in Patients With MDS Who Failed to Respond to Single Agent HMA [Phase 2]
Phase 2 study evaluating adding pracinostat to a hypomethylating agent in patients with myelodysplastic syndrome who did not respond to sing…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant [Phase 2]
Phase 2 trial of T-cell replete haploidentical donor hematopoietic stem cell transplantation with natural killer (NK) cell support in hemato…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological Malignancies [Phase 1, Phase 2]
Phase 1 and Phase 2 results are reported for allogeneic cytokine-induced killer (CIK) cell immunotherapy given to patients who relapsed afte…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: Traditional Chinese Medicine in the Supportive Management of Anaemic and Cytopenic (Leukopenia, Thrombocytopenia) Haematological Disorders [Phase 1, Phase 2]
A completed Phase 1/2 study from Singapore General Hospital evaluated a Traditional Chinese Medicine formulation for supportive management o…
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CLINICAL_TRIALS trial_result · 2017-02-10Clinical Trial Update: 5-Azacytidine With Lenalidomide in Patients With High Risk Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating azacitidine in combination with lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Allogeneic Transplantation From Related Haploidentical Donors [Phase 2]
A Phase 2 clinical trial evaluating allogeneic transplantation from related haploidentical donors for blood cancers and leukemia has complet…
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: ED-TBI Followed By Allogeneic Stem Cell Transplantation For The Treatment Of Refractory AML And Advanced MDS [Phase 2]
Phase 2 trial evaluating external total body irradiation followed by allogeneic stem cell transplantation for refractory acute leukemia and …
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CLINICAL_TRIALS withdrawal · 2016-12-29Clinical Trial Update: Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating CPI-613 for refractory or relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome has been withdrawn.
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CLINICAL_TRIALS research · 2016-12-21Clinical Trial Update: Myelodysplasic Syndromes and Risk Factors for Infection
A clinical trial update exploring risk factors for infection in patients with myelodysplastic syndrome, including high-risk IPSS status.
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Assessment of Body, Liver and Labile Plasma Iron and Their Association With Outcome and Immunological Recovery in Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) Patients Undergoing Allogeneic Stem Cell Transplantation - ALLIVE (ALLogeneic Iron inVEstigators) Observational Trial
An observational study (ALLIVE) completed that evaluated body, liver, and labile plasma iron metrics and their associations with clinical ou…