Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: PENELOPE Observational Study: Prophylaxis and Treatment of Arterial and Venous Thromboembolism
The PENELOPE observational study, which examined prophylaxis and treatment of arterial and venous thromboembolism in patients with hematolog…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating ipilimumab in patients with relapsed or refractory high-risk myelodysplastic syndrome or acute myeloid leukemia h…
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CLINICAL_TRIALS research · 2018-03-20Clinical Trial Update: Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This is a Phase I/II clinical trial evaluating oral panobinostat as maintenance therapy after allogeneic stem cell transplantation in patien…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Non-Myeloablative HLA-Matched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies [Phase 2]
A Phase 2 study of non-Myeloablative HLA-matched ex-vivo T-cell depleted stem cell transplantation for hematologic malignancies was terminat…
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CLINICAL_TRIALS withdrawal · 2018-03-14Clinical Trial Update: Pharmacokinetic and Pharmacodynamic Assessment of Treatment With CPX-351 (Cytarabine: Daunorubicin) Liposome for Injection in Acute Leukemias and MDS Patients With Moderate Hepatic Impairment [Phase 2]
Clinical trial update notes that a Phase 2 study evaluating the pharmacokinetics and pharmacodynamics of CPX-351 in acute leukemias and myel…
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CLINICAL_TRIALS trial_result · 2018-01-23Clinical Trial Update: Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating atorvastatin for prophylaxis of acute graft-versus-host disease in patients undergoing HLA-mon donor hematopoietic …
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CLINICAL_TRIALS trial_result · 2018-01-10Clinical Trial Update: A Study of Combined Deferasirox, Vitamin D and Azacytidine in High Risk MDS [Phase 1, Phase 2]
A combined therapy study (deferasirox, vitamin D, azacytidine) in high-risk myelodysplastic syndromes is in Phase 1/Phase 2 with unknown sta…
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CLINICAL_TRIALS research · 2017-12-08Clinical Trial Update: Effect of Chemotherapy vs No Chemotherapy Pre-transplant to MDS Undergoing Allo-HSCT
This trial compares pre-transplant chemotherapy versus no chemotherapy in patients with myelodysplastic syndrome undergoing allogeneic stem …
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Total Marrow Irradiation for Refractory Acute Leukemia [Phase 1]
A Phase 1 trial evaluating total marrow irradiation for refractory acute leukemia has completed enrollment/status; the study included patien…
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CLINICAL_TRIALS trial_result · 2017-11-30Clinical Trial Update: An Open Label Phase II Pharmacokinetic and Pharmacodynamic Assessment of the Potential for QTc Prolongation Following First Induction Treatment With CPX-351 (Cytarabine:Daunorubicin) Liposome Injection in Acute Leukemias and MDS Patients [Phase 2]
This Phase 2 open-label pharmacokinetic/pharmacodynamic trial evaluated CPX-351 (cytarabine:daunorubicin liposome injection) for potential Q…
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CLINICAL_TRIALS research · 2017-11-29Clinical Trial Update: DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excess [Phase 2]
A Phase 2 clinical trial evaluating DLAAG for acute myeloid leukemia and myelodysplastic syndrome with blast excess, with status currently u…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients [Phase 2]
Phase 2 clinical trial of microtransplantation for refractory or relapsed hematologic malignancies in younger patients was terminated, with …
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CLINICAL_TRIALS trial_result · 2017-09-14Clinical Trial Update: Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS [Phase 1, Phase 2]
A safety study evaluating mocetinostat in combination with azacitidine in patients with myelodysplastic syndrome completed Phase 1 and Phase…
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CLINICAL_TRIALS trial_result · 2017-08-30Clinical Trial Update: Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome [Phase 1]
Phase 1 trial evaluating donor peripheral blood stem cell transplantation in combination with pretargeted radioimmunotherapy for patients wi…
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CLINICAL_TRIALS trial_result · 2017-08-24Clinical Trial Update: Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating chemotherapy followed by unrelated donor stem cell transplantation for blood and immune system cancers; …
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias [Phase 1]
Phase 1 pharmacokinetic study of oral and intravenous clofarabine in high-risk myelodysplastic syndrome and acute leukemias; the trial has c…
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplant [Phase 2]
Phase 2 clinical trial update assessing safety and tolerability of HSC835 in patients with hematological malignancies undergoing single umbi…
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CLINICAL_TRIALS trial_result · 2017-08-09Clinical Trial Update: Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies [Phase 2]
This Phase 2 randomized trial comparing haplo cord blood transplantation versus double umbilical cord blood transplantation for hematologic …
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Decitabine, Vorinostat, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
This Phase 1 trial evaluated the safety and preliminary activity of a three-drug combination—decitabine, vorinostat, and cytarabine—in patie…
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FDA approval · 2017-07-28FDA Approved: AZACITIDINE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approved Dr. Reddy's Laboratories Inc.'s supplemental application for azacitidine. The action pertains to a supplemental filing for the …
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Busulfan/Clofarabine + Allogeneic Stem Cell Transplantation [Phase 2]
This Phase 2 clinical trial update reports results for busulfan and clofarabine conditioning followed by allogeneic stem cell transplantatio…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Post Transplant Donor Lymphocyte Infusion [Phase 2]
Phase 2 clinical trial update for post-transplant donor lymphocyte infusion; the study is terminated with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Clofarabine and Cytarabine in Treating Older Patients With AML or High-Risk MDS [Phase 1, Phase 2]
Clinical trial update of a Phase 1/2 study evaluating the combination of clofarabine and cytarabine in older patients with acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Safety of Peptide Vaccination for Patients With Myelodysplastic Syndrome [Phase 1]
This clinical trial update reports safety findings from a Phase 1 study of a peptide vaccine in patients with myelodysplastic syndrome, with…
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CLINICAL_TRIALS trial_result · 2017-06-29Clinical Trial Update: Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells [Phase 1]
A Phase 1 trial of unrelated umbilical cord blood transplantation augmented with ALDHbr cord blood cells has completed, with the update desc…