Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor natural killer cells and donor stem cell transplant in high-risk myeloid malignancies; completed w…
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT [Phase 2]
Phase 2 trial investigating relapse prophylaxis with N-803 after allogeneic HSCT in AML and MDS patients has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: 5-azacytidine Treatment Versus 5-azacytidine Followed by Allogeneic Stem Cell Transplantation in Elderly Patients With Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 clinical trial comparing 5-azacytidine alone versus 5-azacytidine followed by allogeneic stem cell transplantation in elderly patien…
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: Immunochemotherapy and AlloSCT in Patients With High Risk CD33+ AML/MDS [Phase 2]
Phase 2 clinical trial evaluating immunochemotherapy and allogeneic stem cell transplantation in high-risk CD33+ acute myeloid leukemia and …
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CLINICAL_TRIALS trial_result · 2023-10-26Clinical Trial Update: SCT Plus Immune Therapy in Average Risk AML/MDS [Phase 2]
Phase 2 clinical trial update for SCT plus immune therapy in average-risk acute myeloid leukemia and myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating controllable PRAME-TCR therapy in patients with acute myeloid leukemia, myelodysplastic syndrome, or metastatic u…
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FDA approval · 2023-09-26FDA Approved: DEFERASIROX — Supplemental Application (Bionpharma Inc.)
FDA approved a supplemental application for Deferasirox from Bionpharma Inc. under an ANDA, authorizing an additional regulatory action for …
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CLINICAL_TRIALS trial_result · 2023-09-14Clinical Trial Update: A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor [Phase 2]
Phase II trial evaluating safety and efficacy of subcutaneous plerixafor in related donors of peripheral blood stem cells for various hemato…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation [Phase 2]
Phase 2 study evaluating a combination of Itacitinib, Tacrolimus, and Sirolimus for prevention of graft-versus-host disease in patients with…
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Phase 1/2 Study of CG200745 PPA for Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 study of CG200745 PPA for myelodysplastic syndrome is ongoing with unknown status.
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FDA approval · 2023-08-28FDA Approved: REBLOZYL — Supplemental Application (Celgene Corporation)
FDA approved a supplemental application for Reblozyl (luspatercept) by Celgene Corporation. The action concerns updating the product's label…
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CLINICAL_TRIALS trial_result · 2023-08-04Clinical Trial Update: Sorafenib and Low Dose Cytarabine in Older Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
Clinical trial updating sorafenib combined with low-dose cytarabine in older patients with acute myeloid leukemia or high-risk myelodysplast…
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: 2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II [Phase 1, Phase 2]
This Phase I/II clinical trial evaluated Interleukin-7 for T-cell recovery after haploidentical and cord blood stem cell transplantation and…
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Phase II Study of Lenalidomide and Eltrombopag in Patients With Symptomatic Anemia [Phase 2]
Phase II study of lenalidomide combined with eltrombopag in adults with symptomatic anemia due to myelodysplastic syndromes completed; resul…
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CLINICAL_TRIALS trial_result · 2023-07-18Clinical Trial Update: Matched Targeted Therapy For High-Risk Leukemias and Myelodysplastic Syndrome [NA]
An update on a matched targeted therapy trial for high-risk leukemias and myelodysplastic syndrome; results have been posted and the study i…
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CLINICAL_TRIALS trial_result · 2023-07-12Clinical Trial Update: Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating a vaccine therapy to reduce cytomegalovirus events in patients with hematologic malignancies undergoing donor stem …
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: A Study of Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001) [Phase 1, Phase 2]
Clinical trial update for BOMedemstat in advanced myeloid malignancies (AML and MDS) across Phase 1/2, with and without ATRA; study status c…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioning [Phase 2]
Phase 2 trial update on allogeneic transplantation using timed sequential busulfan and fludarabine conditioning for various hematologic mali…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 clinical trial assessing a combination regimen including filgrastim, cladribine, cytarabine, mitoxantrone, and sorafenib in newly …
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FDA approval · 2023-06-15FDA Approved: CYTARABINE — Supplemental Application (Meitheal Pharmaceuticals Inc.)
FDA approved a supplemental application for Cytarabine from Meitheal Pharmaceuticals Inc., completing a modification to the existing Cytarab…
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating high-dose cyclophosphamide, tacrolimus, and mycophenolate mofetil to prevent graft-versus-host disease in …
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease [Phase 2]
Phase 2 clinical trial investigating salsalate, venetoclax, and decitabine or azacitidine for acute myeloid leukemia and advanced myelodyspl…
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: Efficacy and Safety of FG-4592 for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome (MDS) [Phase 2, Phase 3]
Phase 2/3 trial assessing FG-4592 for anemia in lower-risk myelodysplastic syndrome completed.
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CLINICAL_TRIALS trial_result · 2023-04-27Clinical Trial Update: Reduced Intensity Conditioning Transplant Using Haploidentical Donors [Phase 2]
Phase 2 clinical trial investigating reduced intensity conditioning transplant using haploidentical donors for various hematologic malignanc…
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: Guadecitabine Extension Study [Phase 2]
Phase 2 extension study of guadecitabine in acute myeloid leukemia and myelodysplastic syndrome was terminated; results were posted in 2023.