Myelodysplastic Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-03-15Clinical Trial Update: A Clinical Study of 6MW3211 Monotherapy or Combination Therapy for AML or MDS [Phase 1, Phase 2]
Clinical trial update for 6MW3211 in AML and MDS across Phase 1 and Phase 2
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Phase 2, Open-Label, Single Arm Study, With BST-236 in Adults With R/R AML or Higher-Risk MDS [Phase 2]
Phase 2, open-label, single-arm study evaluating BST-236 in adults with relapsed/refractory AML or higher-risk MDS.
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of pevonedistat plus azacitidine, fludarabine phosphate, and cytarabine in relapsed or refractory acute myeloid leukemia or my…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: Azacitidine in Combination With Venetoclax Treatment for MRD Positive Post Allo-HSCT AML/MDS Patients [Phase 2]
Phase 2 clinical trial update evaluating azacitidine in combination with venetoclax for MRD-positive post allogeneic stem cell transplant AM…
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CLINICAL_TRIALS trial_result · 2023-02-17Clinical Trial Update: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant [Phase 2]
Phase 2 clinical trial evaluating treosulfan, fludarabine phosphate, and total-body irradiation as conditioning for umbilical cord blood tra…
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: Study of REVLIMID (Lenalidomide) Versus Placebo in Patients With Low Risk Myelodysplastic Syndrome [Phase 3]
Phase 3 trial evaluating lenalidomide versus placebo in patients with low-risk myelodysplastic syndrome has been completed.
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CLINICAL_TRIALS trial_result · 2023-02-06Clinical Trial Update: Study to Investigate the Safety and Clinical Activity of GSK3326595 and Other Agents to Treat Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial investigating GSK3326595 and other agents for myelodysplastic syndrome and acute myeloid leukemia has …
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CLINICAL_TRIALS trial_result · 2023-01-31Clinical Trial Update: Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Phase 3]
Phase 3 trial comparing Tacrolimus plus mini-methotrexate versus Tacrolimus plus methotrexate for graft-versus-host disease prevention has c…
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 2]
Phase 2 trial evaluating decidual stromal cells for treatment of steroid-refractory graft-versus-host disease after allogeneic stem cell tra…
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CLINICAL_TRIALS trial_result · 2023-01-04Clinical Trial Update: Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant [Phase 1, Phase 2]
A phase 1/2 safety study evaluating gene-modified donor T-cells after TCRαβ+ depleted stem cell transplant was terminated; results were post…
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies [Phase 2]
Phase 2 clinical trial update on shorter course tacrolimus after non-myeloablative conditioning with related donor PBSCT and high-dose postt…
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CLINICAL_TRIALS trial_result · 2022-10-07Clinical Trial Update: Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow [Phase 2]
Phase 2 trial update on specialized blood cell transplants for cancers of the blood and bone marrow; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-10-04Clinical Trial Update: A Study of Azacitidine in Myelodysplastic Syndrome (MDS) Associated to Systemic Auto-immune and Inflammatory Disorders [Phase 2]
Phase 2 trial evaluating azacitidine in myelodysplastic syndrome associated with systemic autoimmune and inflammatory disorders has complete…
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CLINICAL_TRIALS trial_result · 2022-09-26Clinical Trial Update: Controlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA [Phase 3]
Phase 3 trial comparing rigosertib to physician's choice in MDS patients after failure of hypomethylating agents was terminated.
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating HLA-compatible related or unrelated donors with CD34+ enriched, T-cell depleted peripheral blood stem cell…
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CLINICAL_TRIALS trial_result · 2022-08-05Clinical Trial Update: Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies [Phase 2]
Phase 2 clinical trial evaluating cord blood with T-cell depleted haplo-identical peripheral blood stem cell transplantation for hematologic…
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CLINICAL_TRIALS trial_result · 2022-08-01Clinical Trial Update: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating a combined regimen including iodine-131 monoclonal antibody BC8, fludarabine phosphate, total body irradia…
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CLINICAL_TRIALS trial_result · 2022-07-29Clinical Trial Update: Allo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102) [Phase 2]
Phase 2 trial comparing allogeneic therapy vs hypomethylating agent with best supportive care in myelodysplastic syndrome has completed with…
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CLINICAL_TRIALS trial_result · 2022-06-15Clinical Trial Update: Post Transplant Cyclophosphamide (Cytoxan) for GvHD Prophylaxis [Phase 2]
Phase 2 clinical trial update on post-transplant cyclophosphamide for graft-versus-host disease prophylaxis completed; results posted in 202…
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer [Phase 3]
Phase 3 trial updating safety and efficacy of ATIR101 as an adjunct to haploidentical stem cell transplantation versus post-transplant cyclo…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia [Phase 2]
Phase 2 trial assessing the effect of blood stem cell transplant after chemotherapy in Fanconi Anemia; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: Study of DSP-7888 in Patients With Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 clinical trial update for DSP-7888 in myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies [Phase 3]
Phase 3 clinical trial update on stem cell transplantation from partially HLA-m matched related donors for hematologic malignancies; trial c…
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome [Phase 1, Phase 2]
First-in-human dose-escalation study of SAR440234 in acute leukemia and myelodysplastic syndrome was terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: GVAX vs. Placebo for MDS/AML After Allo HSCT [Phase 2]
Phase 2 clinical trial evaluating GVAX versus placebo for myelodysplastic syndrome and acute myeloid leukemia after allogeneic stem cell tra…