Myelodysplastic Myeloproliferative Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms [Phase 1, Phase 2]
Pacritinib is being studied in Phase 1/2 trials for myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms in adults and…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of BGB-11417 in Participants With Myeloid Malignancies [Phase 1, Phase 2]
BeiGene is testing BGB-11417 in Phase 1/2 trials for myeloid malignancies, including acute myeloid leukemia and myelodysplastic syndromes, w…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating tranexamic acid in patients with myelodysplastic syndromes and acute myeloid leukemia and is currentl…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes [Phase 2]
Phase 2 clinical trial evaluating ruxolitinib before, during, and after hematopoietic cell transplant in older patients with myelofibrosis a…
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CLINICAL_TRIALS withdrawal · 2026-02-13Clinical Trial Update: Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of decitabine, cedazuridine (ASTX727), and ASTX029 (an ERK inhibitor) for patients wit…
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EMA approval · 2025-11-12EMA Authorised: Glivec (imatinib) — Novartis Europharm Limited
The European Medicines Agency authorised Glivec (imatinib) for multiple indications, including precursor cell lymphoblastic leukemia-lymphom…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
This ClinicalTrials.gov update describes an ongoing study that collects tissue, blood, and body fluid samples from patients with hematologic…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating CPI-0610 with and without ruxolitinib in patients with hematologic and myeloproliferative malignancies. …
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: OURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study
A feasibility pilot study evaluating the use of the OURA Ring wearable in patients with myelodysplastic syndromes to explore discovery endpo…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
This clinical trial update describes the use of the PET imaging agent 18F-fluorothymidine (18F-FLT) in cancer patients to assess tumor proli…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Registry of Older Patients With Cancer
This clinical trial registry entry from UNC Lineberger indicates an ongoing recruitment for a registry of older patients with cancer, includ…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantation [Phase 2]
Phase 2 trial evaluating tocilizumab to prevent graft-versus-host disease after cord blood transplantation has been completed.
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG [Phase 3]
Phase 3 randomized trial comparing post-transplant cyclophosphamide versus anti-thymocyte globulin for graft-versus-host disease prophylaxis…
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: A Multicenter Study on the Treatment of MDS/MPN Overlap Syndrome With AZA or Rux Combined With Selinexor [Phase 2]
Phase 2 multicenter trial evaluating azacitidine or ruxolitinib in combination with selinexor for MDS/MPN overlap syndrome; currently enroll…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: Myeloproliferative Neoplasms (MPNs) Patient Registry
An update on the Myeloproliferative Neoplasms (MPNs) Patient Registry sponsored by University Health Network in Toronto, currently recruitin…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms [Phase 1]
The Phase 1 study of TAS1553 in subjects with relapsed or refractory acute myeloid leukemia and other myeloid neoplasms has been terminated.
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CLINICAL_TRIALS trial_result · 2022-03-16Clinical Trial Update: Clinical Study of Venetoclax Combined With Azacytiside in the Treatment of Myelodysplastic/Myeloproliferative Neoplasms in Adults [Phase 2]
Phase 2 clinical trial evaluating venetoclax with azacitidine for adults with myelodysplastic/myeloproliferative neoplasms.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Bone Marrow Transplant in Treating Patients With Hematologic Cancers [Phase 2]
Phase 2 clinical trial update on bone marrow transplant for hematologic cancers (completed).
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CLINICAL_TRIALS trial_result · 2020-07-27Clinical Trial Update: Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial [Phase 3]
Phase 3 clinical trial update focusing on personalized or basic information to aid decision-making for participating in a trial.
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Cholecalciferol in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating cholecalciferol (vitamin D3) for treating patients with myelodysplastic syndromes, completed.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [NA]
ClinicalTrials.gov entry describes termination of a study evaluating donor umbilical cord blood transplantation for various hematologic canc…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating busulfan, fludarabine, and total-body irradiation as conditioning for donor stem cell transplantation …
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant [Phase 2]
This Phase 2 trial evaluated sirolimus, tacrolimus, and antithymocyte globulin to prevent graft-versus-host disease in patients with hematol…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematological Cancer or Other Disease [Phase 2]
Phase 2 trial update describing donor umbilical cord blood transplantation for advanced hematologic cancers, including leukemia, lymphoma, m…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases [NA]
This ClinicalTrials.gov update reports on a completed study evaluating whether music can reduce anxiety and pain in adults undergoing bone m…