Mycobacterium Avium Complex Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Clinical Characteristics and Immune Escape Mechanism of Nontuberculous Mycobacterial Lung Disease in South China
This clinical trial from Sun Yat-sen University investigates clinical characteristics and immune escape mechanisms of non-tuberculous mycoba…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Safety, Immunogenicity, and Efficacy of Therapeutic Mycobacterium Bovis BCG (BOOST) [Phase 2]
Phase 2 clinical trial evaluating safety, immunogenicity, and efficacy of a therapeutic Mycobacterium bovis BCG (BOOST) for nontuberculous m…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex [Phase 3]
Phase 3 trial update validating patient-reported outcome measures in participants with nontuberculous mycobacterial pulmonary disease caused…
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: M. Avium WGS During Mav-PD Treatment
This ClinicalTrials.gov entry reports a recruiting study sponsored by University Health Network (Toronto) investigating whole-genome sequenc…
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FDA approval · 2023-02-10FDA Approved: ARIKAYCE — Supplemental Application (Insmed Incorporated)
FDA approved a supplemental application for ARIKAYCE (amikacin liposome inhalation suspension) from Insmed Incorporated. This action updates…
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FDA approval · 2021-12-17FDA Approved: RIFABUTIN — Original Application (ANI Pharmaceuticals, Inc.)
FDA approved rifabutin under an original application for ANI Pharmaceuticals, Inc. (ANDA).
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals. [Phase 2]
Phase II/III trial investigating a rifampin-containing regimen for disseminated Mycobacterium avium complex infection in HIV-infected indivi…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients [Phase 3]
Phase 3 trial evaluating clarithromycin and rifabutin, alone or in combination, for prevention of MAC or disseminated MAC disease in HIV-inf…
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FDA approval · 2021-09-15FDA Approved: RIFABUTIN — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for Rifabutin submitted by Mylan Pharmaceuticals Inc. under NDA 050689.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Adjuvant Cytokine Therapy to Treat Pulmonary Mycobacterium Avium Complex Infection [Phase 1]
A Phase 1 clinical trial evaluating adjuvant cytokine therapy for pulmonary Mycobacterium avium complex infection has completed.
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium Complex [Phase 3]
A Phase 3 trial evaluating rifabutin for Mycobacterium avium complex infection has completed, assessing its effectiveness in treating non-tu…
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CLINICAL_TRIALS trial_result · 2017-05-23Clinical Trial Update: Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM) [Phase 4]
Phase 4 trial update reporting completion of a study evaluating clarithromycin for infections caused by non-tuberculous mycobacteria, includ…
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FDA approval · 2015-07-01FDA Approved: RIFABUTIN — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for Rifabutin from Mylan Pharmaceuticals Inc., updating labeling and approved uses.
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CLINICAL_TRIALS trial_result · 2015-01-16Clinical Trial Update: The Safety and Effectiveness of Clarithromycin in the Prevention of Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients [NA]
A completed clinical trial evaluating the safety and effectiveness of clarithromycin for preventing Mycobacterium avium complex infection in…
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CLINICAL_TRIALS trial_result · 2015-01-16Clinical Trial Update: The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS [NA]
A completed clinical trial evaluated the safety and effectiveness of adding clofazimine to clarithromycin plus ethambutol for treating Mycob…
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients [Phase 2]
A Phase 2 clinical trial evaluating treatment for Mycobacterium avium complex infection in HIV-infected patients has completed.
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients [NA]
This update reports results from a completed trial assessing the safety and effectiveness of rifabutin when combined with either clarithromy…
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Mycobacterium Avium Intracellulare Complex (MAC) Study
A Mayo Clinic-sponsored clinical trial investigating treatment for Mycobacterium avium complex infection has completed.
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS [Phase 2]
Phase II study assessing the safety and efficacy of clarithromycin for disseminated Mycobacterium avium complex infection in patients with A…
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CLINICAL_TRIALS trial_result · 2008-08-04Clinical Trial Update: The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS [Phase 1]
A Phase 1 trial evaluating the safety and preliminary effectiveness of combining clarithromycin with zidovudine or didanosine for Mycobacter…
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CLINICAL_TRIALS trial_result · 2008-07-30Clinical Trial Update: A Study to Examine the Effects of Stopping Preventive Therapy for Disseminated Mycobacterium Avium Complex (DMAC) in HIV-Positive Patients
A completed clinical trial assessed the effects of stopping preventive therapy for Mycobacterium avium complex infection in HIV-positive pat…
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CLINICAL_TRIALS trial_result · 2008-04-03Clinical Trial Update: Clofazamine for the Treatment of Mycobacterium Avium Intracellulare(MAI)
A Yale-sponsored clinical trial evaluating clofazimine for Mycobacterium avium complex infection has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex Infections [Phase 2]
A Phase II randomized, double-blind, placebo-controlled trial evaluated inhaled interferon gamma-1b in combination with antimycobacterial th…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex Infection [Phase 1]
Phase 1 trial evaluating subcutaneously administered interleukin-12 in HIV-infected patients with disseminated Mycobacterium avium complex i…