Muscle Spasticity
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals [Phase 1]
Phase 1 single and multiple ascending dose study of MTR-601 in healthy individuals with results posted after completion.
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Comparison of Two Botox Injection Techniques to Improve Gait [NA]
This completed clinical trial compared two Botox (onabotulinumtoxinA) injection techniques to improve gait in people with muscle spasticity …
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity [NA]
A clinical trial evaluating MyoRegulator for post-stroke upper limb spasticity has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: H-reflex in Spastic Lower Limb Cryoneurotomy
A clinical trial is evaluating the use of cryoneurotomy to modify the H-reflex for treating muscle spasticity in the lower limbs.
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy? [Phase 4]
Phase 4 trial update exploring whether Botulinum Toxin A improves walking in children with cerebral palsy and muscle spasticity.
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: The Movement of Botulinum Toxin Through the Lateral Gastrocnemius Muscle in Humans: An Expanded Examination [Phase 4]
Phase 4 trial investigating the movement of botulinum toxin through the lateral gastrocnemius muscle in humans for stroke-related muscle spa…
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CLINICAL_TRIALS trial_result · 2021-12-07Clinical Trial Update: CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase3) [Phase 3]
Phase 3 clinical trial update for CORETOX® in post-stroke upper limb spasticity has completed.
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Altering Activation Patterns Post-stroke [NA]
A completed clinical trial investigated altering activation patterns after stroke to address motor impairment and spasticity; results have b…
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: Intrathecal (IT) Baclofen Drug Distribution [Phase 4]
Phase 4 trial updating intrathecal baclofen distribution for muscle spasticity; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury [Phase 2]
Phase 2 clinical trial update evaluating XP19986 for safety and efficacy in spasticity due to spinal cord injury completed.
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke [Phase 1, Phase 2]
Clinical trial updates on trans-spinal direct current stimulation (tsDCS) for hand spasticity after stroke, covering Phase 1 and Phase 2; st…
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity [Phase 3]
Open-label Phase 3 trial of Botox in pediatric upper limb spasticity has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-21Clinical Trial Update: BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity [Phase 3]
Phase 3 open-label trial updating pediatric lower limb spasticity treatment with BOTOX, completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-29Clinical Trial Update: Effects on Quality of Life Following Dysport Treatment in Post-stroke Spasticity of the Arm [Phase 4]
Phase 4 clinical trial update assessing quality of life after Dysport treatment for post-stroke spasticity of the arm.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity [Phase 4]
Phase 4 clinical trial update evaluating botulinum therapy for early post-stroke spasticity in Asian population; study completed.
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CLINICAL_TRIALS trial_result · 2019-03-29Clinical Trial Update: Meditoxin® Treatment in Patients With Post Stroke Upper Limb Spasticity [Phase 4]
Phase 4 clinical trial update for Meditoxin treatment in patients with post-stroke upper limb spasticity completed.
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CLINICAL_TRIALS trial_result · 2018-08-14Clinical Trial Update: BOTOX® Treatment in Pediatric Upper Limb Spasticity [Phase 3]
Phase 3 clinical trial update for BOTOX® in pediatric upper limb spasticity has completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-03-20Clinical Trial Update: Effect of Botox and Vibration on Bone in Children With Cerebral Palsy [NA]
Clinical trial update on the effects of Botox (onabotulinumtoxinA) and vibration therapy on bone in children with cerebral palsy. The study …
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Bilateral Versus Unilateral Task Retraining Using the SaeboFlex Orthosis [NA]
A clinical trial comparing bilateral versus unilateral task retraining using the SaeboFlex orthosis was terminated; sponsor is University of…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Physiologic Studies of Spasticity
A completed clinical trial update detailing physiologic studies of spasticity conducted by the National Institute of Neurological Disorders …
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Dysport® Pediatric Lower Limb Spasticity Follow-on Study [Phase 3]
Phase 3 follow-on study for Dysport in pediatric lower limb spasticity due to cerebral palsy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity [Phase 3]
Phase 3 trial evaluating onabotulinumtoxinA for upper limb spasticity in adults after stroke. The study was terminated and results were post…
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: Dysport® Pediatric Lower Limb Spasticity Study [Phase 3]
A Phase 3 clinical trial update for Dysport in pediatric lower limb spasticity associated with cerebral palsy has completed with results pos…
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Botulinum Toxin (BOTOX) for Cerebral Palsy [Phase 2]
A Phase 2 clinical trial evaluating botulinum toxin (BOTOX) for cerebral palsy-associated muscle spasticity has completed.
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CLINICAL_TRIALS trial_result · 2016-03-25Clinical Trial Update: Radial Extracorporeal Shock Wave Therapy for Spastic Plantar Flexor Muscles in Young Children With Cerebral Palsy [NA]
The clinical trial investigating radial extracorporeal shock wave therapy for spastic plantar flexor muscles in young children with cerebral…