Muscle Spasticity
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Results: Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals [Phase 1]
Phase 1 single and multiple ascending dose study of MTR-601 in healthy individuals with results posted after completion.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Peripheral Modulation of Muscle Stiffness and Spasticity [Phase 2]
Phase 2 clinical trial from Johns Hopkins University evaluating peripheral modulation to reduce muscle stiffness and spasticity; the study i…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study [NA]
A recruiting clinical trial comparing upper limb surgery with botulinum toxin for spasticity in patients with spinal cord injury, stroke, or…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Comparison of Two Botox Injection Techniques to Improve Gait [NA]
This completed clinical trial compared two Botox (onabotulinumtoxinA) injection techniques to improve gait in people with muscle spasticity …
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: SIRS-ESWT Trial: Shoulder Internal Rotator Spasticity Trial Treated With Extracorporeal Shock Wave Therapy Trial [NA]
The document reports that the SIRS-ESWT trial evaluating extracorporeal shock wave therapy for shoulder internal rotator spasticity in strok…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Dry Needling for Spasticity in Stroke [NA]
This clinical trial update notes ongoing research on using dry needling to treat spasticity after stroke, with the study currently active bu…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Therapeutic Photobiomodulation and Tretament of Spasticity [Phase 2, Phase 3]
A phase 2/3 clinical trial is evaluating photobiomodulation using low-level laser therapy to treat muscle spasticity in cerebral palsy, and …
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Effect of Transcutaneous Auricular Nerve Stimulation vs Body Rocking Exercises on Spasticity of Upper Limb [NA]
This clinical trial update examines transcutaneous auricular nerve stimulation versus body rocking exercises for upper-limb spasticity. The …
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FDA approval · 2024-12-17FDA Approved: DIAZEPAM — Supplemental Application (Lupin Pharmaceuticals,Inc.)
FDA approved a supplemental application for diazepam submitted by Lupin Pharmaceuticals, Inc. The approval relates to changes under the appr…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Upper-limb Active Function and Botulinum Toxin a [NA]
This clinical trial in Toulouse is evaluating Botulinum toxin A to improve upper-limb function in stroke patients with muscle spasticity. Th…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity [NA]
A clinical trial evaluating MyoRegulator for post-stroke upper limb spasticity has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: H-reflex in Spastic Lower Limb Cryoneurotomy
A clinical trial is evaluating the use of cryoneurotomy to modify the H-reflex for treating muscle spasticity in the lower limbs.
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FDA approval · 2024-04-25FDA Approved: DIAZEPAM — Original Application (Alembic Pharmaceuticals Limited)
FDA approves Alembic Pharmaceuticals Limited's original application for a generic diazepam product. This approval supports a generic version…
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FDA approval · 2023-11-22FDA Approved: DIAZEPAM — Supplemental Application (Sunrise Pharmaceutical, Inc.)
The FDA approved a supplemental application for Diazepam submitted by Sunrise Pharmaceutical, Inc.
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FDA approval · 2023-07-10FDA Approved: DIAZEPAM — Supplemental Application (Oceanside Pharmaceuticals)
FDA approved a supplemental application for Diazepam from Oceanside Pharmaceuticals.
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FDA approval · 2022-06-10FDA Approved: TIZANIDINE HYDROCHLORIDE — Supplemental Application (Alembic Pharmaceuticals Limited)
The FDA approved a supplemental application for a generic tizanidine hydrochloride product submitted by Alembic Pharmaceuticals Limited unde…
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy? [Phase 4]
Phase 4 trial update exploring whether Botulinum Toxin A improves walking in children with cerebral palsy and muscle spasticity.
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CLINICAL_TRIALS trial_result · 2021-12-29Clinical Trial Update: The Movement of Botulinum Toxin Through the Lateral Gastrocnemius Muscle in Humans: An Expanded Examination [Phase 4]
Phase 4 trial investigating the movement of botulinum toxin through the lateral gastrocnemius muscle in humans for stroke-related muscle spa…
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CLINICAL_TRIALS trial_result · 2021-12-07Clinical Trial Update: CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase3) [Phase 3]
Phase 3 clinical trial update for CORETOX® in post-stroke upper limb spasticity has completed.
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Altering Activation Patterns Post-stroke [NA]
A completed clinical trial investigated altering activation patterns after stroke to address motor impairment and spasticity; results have b…
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FDA approval · 2021-05-17FDA Approved: DIAZEPAM — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for diazepam filed by Hikma Pharmaceuticals USA Inc., marking regulatory clearance for an additi…
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: Intrathecal (IT) Baclofen Drug Distribution [Phase 4]
Phase 4 trial updating intrathecal baclofen distribution for muscle spasticity; results posted after completion.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: A Safety and Efficacy Study of XP19986 in Subjects With Spasticity Due to Spinal Cord Injury [Phase 2]
Phase 2 clinical trial update evaluating XP19986 for safety and efficacy in spasticity due to spinal cord injury completed.
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FDA approval · 2021-02-08FDA Approved: DIAZEPAM — Supplemental Application (Natco Pharma USA LLC)
FDA approved a supplemental application for Diazepam (generic) from Natco Pharma USA LLC under an ANDA. The action confirms approval of the …
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FDA approval · 2021-02-05FDA Approved: DIAZEPAM INTENSOL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for Diazepam Intensol from Hikma Pharmaceuticals USA Inc.