Muscle-invasive Bladder Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: A Study of TAR-200 in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Ineligible for or Refuse Cisplatin-based Chemotherapy and Who Are Unfit for Radical Cystectomy [Phase 1]
This is a Phase 1 clinical trial update for TAR-200 in patients with muscle-invasive bladder cancer who are ineligible for cisplatin-based c…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Daratumumab in Treating Patients with Muscle Invasive Bladder Cancer or Metastatic Kidney Cancer [EARLY_Phase 1]
This early-phase 1 trial update reports completion of a study evaluating daratumumab in patients with muscle-invasive bladder cancer and met…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Pembrolizumab With Chemoradiotherapy as Treatment for Muscle Invasive Bladder Cancer [Phase 2]
A Phase 2 trial evaluating pembrolizumab in combination with chemoradiotherapy for muscle-invasive bladder cancer has completed, with result…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: A Study to Evaluate Treatment Preferences for Japanese Participants With Muscle-invasive Urothelial Carcinoma of the Bladder
A completed clinical trial evaluating treatment preferences in Japanese participants with muscle-invasive urothelial carcinoma of the bladde…
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL) [Phase 2]
SWOG's Phase 2 trial evaluating adding avelumab to gemcitabine and carboplatin before surgery in cisplatin-ineligible muscle-invasive urinar…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Durvalumab Plus Tremelimumab With Concurrent Radiotherapy for Localized Muscle Invasive Bladder Cancer Treated With a Selective Bladder Preservation Approach [Phase 2]
Phase 2 trial evaluating durvalumab plus tremelimumab with concurrent radiotherapy for localized muscle-invasive bladder cancer treated with…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Study of CAbozantinib in Combination with AtezolizumaB for Muscle-Invasive BladdEr Cancer [Phase 2]
Phase 2 clinical trial evaluating cabozantinib in combination with atezolizumab for muscle-invasive bladder cancer; the study is currently a…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Sasanlimab As Maintenance Treatment Based on Clinical Response to Neoadjuvant Treatment in Molecularly Categorized Muscle Invasive Bladder Cancer Patients [Phase 2]
Phase 2 clinical trial evaluating sasanlimab as maintenance therapy after neoadjuvant treatment in molecularly categorized muscle-invasive b…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Safety and Tolerability of TAR-200 and Nivolumab in Subjects With Muscle-Invasive Bladder Cancer [Phase 1]
Phase 1 trial assessing the safety and tolerability of TAR-200 in combination with nivolumab in muscle-invasive bladder cancer; the study ha…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Gemcitabine, Cisplatin, Plus Nivolumab in Patients With Muscle-invasive Bladder Cancer With Selective Bladder Sparing [Phase 2]
Phase 2 trial evaluating the combination of gemcitabine, cisplatin, and nivolumab in muscle-invasive bladder cancer with selective bladder-s…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer [Phase 3]
Phase 3 trial comparing Nivolumab plus Bempegaldesleukin versus Nivolumab alone and standard of care in cisplatin-ineligible muscle-invasive…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: AGEN1884 Plus AGEN2034 Combined With Cisplatin-Gemcitabine for Muscle-Invasive Bladder Cancer [Phase 2]
Phase 2 trial evaluating AGEN1884 plus AGEN2034 with cisplatin-gemcitabine for muscle-invasive bladder cancer was terminated, with results p…
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: A Study of RC48-ADC Combined With JS001 For Perioperative Treatment of Muscle-Invasive Bladder Cancer [Phase 2]
Phase 2 trial update evaluating RC48-ADC combined with JS001 as perioperative treatment for muscle-invasive bladder cancer.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: A Study of RC48-ADC Combined With AK104 For Perioperative Treatment of Muscle-Invasive Bladder Cancer [Phase 2]
Phase 2 trial evaluating RC48-ADC in combination with AK104 for perioperative treatment of muscle-invasive bladder cancer.
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: RC48 Combined With Toripalimab and Radiotherapy for Bladder Sparing Treatment in MIBC [Phase 2]
Phase 2 trial evaluating RC48 plus toripalimab and radiotherapy for bladder-sparing treatment in muscle invasive bladder cancer with HER2 ex…
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CLINICAL_TRIALS trial_result · 2023-08-24Clinical Trial Update: Cadonilimab Plus Nab-Paclitaxel for Recurrent or Metastatic Muscle Invasive Bladder Cancer [Phase 2]
Phase 2 trial update of cadonilimab plus nab-paclitaxel for recurrent or metastatic muscle-invasive bladder cancer (bladder cancer).
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CLINICAL_TRIALS trial_result · 2023-07-18Clinical Trial Update: Neoadjuvant Pembrolizumab for Muscle-invasive Urothelial Bladder Carcinoma [Phase 2]
Phase 2 trial update on neoadjuvant pembrolizumab for muscle-invasive urothelial bladder carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2023-01-20Clinical Trial Update: Study Evaluating Neoadjuvant Pembrolizumab Monotherapy in Patients With Muscle-Invasive Bladder Cancer to Explore in Vivo the Mechanisms of Action of Pembrolizumab [Phase 2]
A Phase 2 neoadjuvant trial assessing pembrolizumab monotherapy in muscle-invasive bladder cancer to study mechanisms of action.
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CLINICAL_TRIALS trial_result · 2022-12-28Clinical Trial Update: Comprehensive Bladder Preservation Therapy on Patients With Muscle Invasive Bladder Cancer [Phase 2]
Phase 2 clinical trial update on bladder-preservation therapy for muscle-invasive bladder cancer.
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CLINICAL_TRIALS trial_result · 2022-11-30Clinical Trial Update: Perioperative Tislelizumab Combined With Nab-Paclitaxel for Muscle-invasive Urothelial Bladder Carcinoma [Phase 2]
Phase 2 trial evaluating perioperative tislelizumab with nab-paclitaxel for muscle-invasive urothelial bladder cancer shows an ongoing study…
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CLINICAL_TRIALS trial_result · 2022-10-26Clinical Trial Update: Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder cáncer [Phase 2]
Phase 2 trial evaluating atezolizumab given concurrently with radiotherapy in patients with muscle-invasive bladder cancer.
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CLINICAL_TRIALS trial_result · 2022-08-18Clinical Trial Update: Bladder Sparing Treatment of Tislelizumab, Gemcitabine and Cisplatin for Patients With PD-L1 Positive Muscle Invasive Bladder Cancer [Phase 2]
Phase 2 trial update investigating a bladder-sparing regimen of tislelizumab plus gemcitabine and cisplatin for PD-L1 positive muscle-invasi…
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CLINICAL_TRIALS trial_result · 2022-06-13Clinical Trial Update: Perioperative Tislelizumab Combined With Nab-Paclitaxel for Muscle-invasive Urothelial Bladder Cancer: A Multicenter Study [Phase 2]
A Phase 2 multicenter trial evaluating perioperative tislelizumab combined with nab-paclitaxel for muscle-invasive urothelial bladder cancer…
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: An Open Label, Single-arm, Phase 2 Study of Neoadjuvant Nivolumab and Nab-paclitaxel Before Radical Cystectomy for Patients With Muscle-invasive Bladder Cancer (NURE-Combo) [Phase 2]
Phase 2 open-label study evaluating neoadjuvant nivolumab with nab-paclitaxel prior to radical cystectomy in muscle-invasive bladder cancer …
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Neoadjuvant Treatment of Upper Urinary and Muscular Invasive Bladder Urothelial Carcinoma [Phase 2]
Phase 2 neoadjuvant trial in upper urinary tract urothelial carcinoma and muscle-invasive bladder cancer; status not provided.