Muscle-invasive Bladder Cancer
📧 Sign up to get email alerts when something new happens for Muscle-invasive Bladder Cancer.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: A Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin Combined With PD-1 Inhibitor and Radiotherapy as Bladder-preserving Therapy in Patients With Localized HER2-high Expressing Muscle-invasive Bladder Urothelial Carcinoma Following Maximal Transurethral Resection [Phase 2]
Phase 2 trial assessing Disitamab Vedotin combined with a PD-1 inhibitor and radiotherapy as a bladder-preserving treatment for localized HE…
-
CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: MRI-Guided Bladder Preservation Program For Patients With Muscle Invasive Bladder Cancer [NA]
This entry describes an MRI-guided bladder preservation trial for muscle-invasive bladder cancer, which is currently not yet recruiting.
-
CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Pan-tumor MRD Study
Paradigm Health's Pan-tumor MRD study (NCT06605404) is currently recruiting across several solid tumor indications including bladder, esopha…
-
CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: NEO-BLAST: Neoadjuvant Therapy for Bladder Cancer Followed by Active Surveillance vs Treatment [Phase 2, Phase 3]
This clinical trial update describes the NEO-BLAST study evaluating neoadjuvant therapy for bladder cancer followed by active surveillance v…
-
CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Treatment Expedition With MRI Processing and Optimization for Muscle Invasive Bladder Cancer [Phase 3]
Phase 3 clinical trial update investigating MRI-based processing and optimization for muscle-invasive bladder cancer; the study is currently…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Observational Clinical Study of Patients With Muscle - Invasive Bladder Cancer Undergoing Bladder Preservation Therapy After Neoadjuvant Therapy
This observational clinical study evaluates outcomes of patients with muscle-invasive bladder cancer undergoing bladder preservation after n…
-
CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: A Study of Risk Enabled Therapy After Neoadjuvant Immunochemotherapy for Bladder Cancer [Phase 2]
This is a Phase 2 clinical trial evaluating risk-enabled therapy after neoadjuvant immunochemotherapy for muscle-invasive bladder cancer.
-
CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Clinical Study on the Treatment of MIBC Patients With SHR-A2102 Injection Combined With Adebrelimab (SHR-1316) [Phase 2, Phase 3]
This clinical trial update indicates SHR-A2102 in combination with Adebrelimab (SHR-1316) is being studied for muscle-invasive bladder cance…
-
CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: A Multicenter Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)
Recruitment is ongoing for a multicenter prospective cohort study evaluating urinary microscopic residual disease as a method to monitor rec…
-
CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Disitamab Vedotin Combined With Ivonescimab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer [Phase 1, Phase 2]
Clinical trial update for a Phase 1/2 study of Disitamab Vedotin combined with Ivonescimab in cisplatin-ineligible muscle-invasive bladder c…
-
CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Role of NAC in cT0 Muscle-invasive Bladder Cancer After Maximal TURBt [Phase 3]
A Phase 3 clinical trial evaluating the role of N-acetylcysteine (NAC) in patients with cT0 muscle-invasive bladder cancer following maximal…
-
CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Pilot Study on Rutin Combined With Tislelizumab and GC (Gemcitabine and Cisplatin) as Neoadjuvant Therapy for Platinum-refractory Muscle-invasive Bladder Cancer [Phase 1]
Phase 1 pilot trial evaluating rutin in combination with tislelizumab and gemcitabine/cisplatin as neoadjuvant therapy for platinum-refracto…
-
CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Surveillance of the Genetic Signature in Circulating Tumor DNA for Guiding Adjuvant Chemotherapy in Urothelial Carcinoma [Phase 2]
Phase 2 clinical trial investigating whether a circulating tumor DNA genetic signature can guide adjuvant chemotherapy decisions in patients…
-
CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors [Phase 2, Phase 3]
This clinical trial update notes a modular Phase 2/Phase 3 study of sEphB4-HSA in EphrinB2-high solid tumors, with recruitment ongoing for m…
-
CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Adjuvant Sacituzumab Govitecan and Nivolumab in Muscle-Invasive Urothelial Carcinoma At High-Risk Recurrence [Phase 2]
Phase 2 trial evaluating adjuvant sacituzumab govitecan in combination with nivolumab for high-risk, resected muscle-invasive urothelial car…
-
CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer [Phase 2]
Phase 2 trial evaluating intravenous high-dose ascorbate with gemcitabine and carboplatin for muscle-invasive bladder cancer; the study is c…
-
CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Tetra-modality Bladder Preservation Strategies in Muscle-invasive Bladder Cancer: TURBT+ Chemo/Immunotherapy+ Radiation Therapy+ Maintenance Immunotherapy vs. W&W [Phase 2]
Phase 2 trial evaluating a four-modality bladder-preservation strategy (TURBT with chemo/immunotherapy, radiation, and maintenance immunothe…
-
CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients with Muscle Invasive Bladder Cancer [Phase 2]
A Phase 2 clinical trial is evaluating whether 18F-FDG-PET-CT improves risk stratification and guides treatment decisions for patients with …
-
CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Pre-Habilitation with Mindfulness and Exercise for Patients Undergoing Radical Cystectomy (PRIMER Trial) [NA]
A clinical trial from University of Virginia is investigating pre-habilitation with mindfulness and exercise for bladder cancer patients und…
-
CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Adjuvant Radiotherapy in Patients With Pathological High-risk Bladder Cancer (GETUG-AFU 30) [NA]
This clinical trial update covers GETUG-AFU 30, a study on adjuvant radiotherapy for patients with pathological high-risk muscle-invasive bl…
-
CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating RC48 (disitamab vedotin) in combination with toripalimab as neoadjuvant therapy for cisplatin-ineligible muscle-i…
-
CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Hypofractionated IMRT With Concurrent Chemotherapy in Muscle-invasive Bladder Cancer (HIRACUM) [NA]
A clinical trial update for HIRACUM evaluating hypofractionated IMRT with concurrent chemotherapy in muscle-invasive bladder cancer, current…
-
CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992) [Phase 3]
This clinical trial update describes the ongoing Phase 3 study MK-3475-992 (KEYNOTE-992) evaluating pembrolizumab plus chemoradiotherapy ver…
-
CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging [NA]
Completed clinical trial evaluating the impact of positron emission tomography (PET) imaging on staging for muscle-invasive bladder cancer.
-
CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Cisplatin, Nab-paclitaxel, Nivolumab With Radiotherapy After Resection of Non-Metastatic Muscle Invasive Bladder Cancer [Phase 2]
Phase 2 trial evaluating cisplatin, nab-paclitaxel, and nivolumab with radiotherapy after resection in non-metastatic muscle-invasive bladde…