Multiple Organ Dysfunction Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS [Phase 3]
Phase 3 trial evaluating GM-CSF to reverse immunoparalysis in pediatric sepsis-induced MODS has completed.
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: ICU Admission Diagnoses and ICU Mortality
This completed clinical trial update from Ataturk University analyzes ICU admission diagnoses and ICU mortality in patients with sepsis-rela…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Mechanisms for Organ Dysfunction in Covid-19
This completed study from Uppsala University explored the mechanisms behind organ dysfunction in COVID-19. It encompassed sepsis-related org…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock [NA]
A completed clinical trial (NCT05874895) evaluated manual lymphatic drainage to improve outcomes in patients with sepsis and septic shock wi…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Hemoperfusion Efferon LPS During Cardiac Surgery Using Cardiopulmonary Bypass [NA]
The clinical trial evaluating hemoperfusion with Efferon LPS during cardiac surgery using cardiopulmonary bypass has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia
This trial update reports the incidence of acute kidney injury and identified risk factors in newborns with congenital diaphragmatic hernia,…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Modulation of Microbiota Metabolism in Cardiac Surgery Patients [NA]
This document reports the completion of a clinical trial evaluating modulation of microbiota metabolism in cardiac surgery patients, with a …
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Pediatric Immune Response to Multi-Organ Dysfunction [NA]
This completed pediatric trial evaluated the immune response in children with Multiple Organ Dysfunction Syndrome. No specific therapeutic i…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Infusion of Prostacyclin vs Placebo for 72-hours in Trauma Patients With Haemorrhagic Shock Suffering From Organ Failure [Phase 2]
Phase 2 trial comparing a prostacyclin infusion to placebo over 72 hours in trauma patients with hemorrhagic shock and multi-organ dysfuncti…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients [Phase 2]
Phase 2 clinical trial update evaluating eculizumab for thrombotic microangiopathy/atypical hemolytic uremic syndrome–associated multiple or…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality [Phase 4]
Phase 4 trial exploring the role of ulinastatin in preventing severe sepsis, septic shock, and related morbidity and mortality.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Early Metabolic Resuscitation for Septic Shock [Phase 2]
Phase 2 trial evaluating early metabolic resuscitation for septic shock was terminated, with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck [NA]
This document reports a completed clinical trial evaluating the prevention of severe acute respiratory failure in patients treated with PROO…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ Failure
A completed clinical trial evaluating whether TCF7L2 genetic polymorphisms influence glycemic control in ICU patients with organ failure.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients
A clinical trial (NCT03489577) investigating post-traumatic inhibition of the innate and adaptive immune system in severely injured patients…
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CLINICAL_TRIALS trial_result · 2017-08-14Clinical Trial Update: Prospective Analysis of Septic Associated Encephalopathy Using the Non-invasive Acoustocerebrography-ACG
A completed prospective clinical trial evaluating septic-associated encephalopathy using non-invasive Acoustocerebrography-ACG.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients [Phase 4]
Phase 4 pharmacokinetic study comparing two high-dose regimens of intravenous vitamin C in critically ill patients, including those with sep…
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Intraoperative Dialysis in Liver Transplantation [NA]
The University of Alberta-sponsored intraoperative dialysis trial in liver transplantation (NCT01575015) has been terminated. The study targ…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock
A clinical trial update reporting results of NT-proBNP assessment in ICU patients with shock after surgery or trauma, including inflammatory…
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients [Phase 2]
Phase 2 trial evaluating the effect of docosahexaenoic acid on inflammatory response and clinical outcomes in surgical patients with severe …
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation [NA]
This trial update reports on the tolerance and safety of a duodenal probe used to monitor microcirculation in patients with Multiple Organ D…
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CLINICAL_TRIALS trial_result · 2016-08-02Clinical Trial Update: Supplemental Parenteral Nutrition in Critically Ill Adults: A Pilot Randomised Controlled Trial [Phase 2, Phase 3]
The document reports that a pilot randomized trial evaluating supplemental parenteral nutrition in critically ill adults across Phase 2 and …
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CLINICAL_TRIALS trial_result · 2016-06-14Clinical Trial Update: Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children
A pediatric clinical trial evaluated plasma response and outcomes in children with septic shock and thrombocytopenia-associated multiple org…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients
Clinical trial update on BK virus-associated renal dysfunction in postoperative/posttraumatic critically ill patients. The study status is c…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Sedation Optimisation Strategy (S.O.S.) Ventilation [Phase 3]
Phase 3 clinical trial update for the Sedation Optimisation Strategy (S.O.S.) in ventilation has completed. The trial was sponsored by Unive…