Motor Neuron Disease
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: Patients With ALS and Other Motor Disorders Will be Treated With Mesenchymal Cell Exosome Solution [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating a Mesenchymal Cell Exosome Solution in patients with amyotro…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Dose-Escalation, Safety and Pharmacokinetic Study of IC14 in Motor Neurone Disease [Phase 1]
Phase 1 dose-escalation study evaluating safety, tolerability and pharmacokinetics of IC14 in motor neuron disease/ALS; the trial has comple…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease [Phase 1]
Open-label extension Phase 1 trial of Monepantel in individuals with motor neuron disease has completed.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
The Phase 2 Meridian trial evaluating pegcetacoplan in adults with amyotrophic lateral sclerosis was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: MN4000 for Treatment of CF and MND Patients in the Home Setting [NA]
Results for a completed clinical trial (NCT03797677) evaluating MN4000 for home-based treatment of cystic fibrosis and motor neuron disease …
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CLINICAL_TRIALS trial_result · 2023-07-20Clinical Trial Update: Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial investigating metabolic flexibility as a therapeutic approach for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: Efficacy of Cannabinoids in Amyotrophic Lateral Sclerosis or Motor Neurone Disease [Phase 3]
Phase 3 clinical trial updating the efficacy of cannabinoids in amyotrophic lateral sclerosis (ALS) / motor neuron disease.
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy [Phase 1, Phase 2]
Clinical trial updates the effects of functional exercise in patients with spinal bulbar muscular atrophy (SBMA) across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: EncoreAnywhere Use in Motor Neurone Disease [NA]
A completed clinical trial update describing the use of EncoreAnywhere in motor neuron disease, sponsored by Sheffield Teaching Hospitals NH…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Telehealth in Motor Neurone Disease [NA]
This clinical trial examining telehealth for motor neuron disease has completed.
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CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease [Phase 2, Phase 3]
This clinical trial update reports on the safety and efficacy of a Cannabis Sativa Extract for spasticity in motor neuron disease and ALS. T…
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: Assessment of the Effects of Sheffield Support Snood in MND Patients [NA]
This document reports the completion of a clinical trial assessing the effects of the Sheffield Support Snood in patients with motor neuron …
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Pennsylvania Consortium: Clinical Database
The Pennsylvania Consortium: Clinical Database trial (NCT00718445) sponsored by Drexel University College of Medicine was terminated; it inv…
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CLINICAL_TRIALS trial_result · 2016-05-11Clinical Trial Update: Study of Electrical Impedance Myography (EIM) in ALS
This update reports on the completed clinical trial evaluating Electrical Impedance Myography (EIM) in amyotrophic lateral sclerosis and rel…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS)
This document reports the completion of a clinical trial evaluating the efficacy of noninvasive ventilation in amyotrophic lateral sclerosis…
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CLINICAL_TRIALS trial_result · 2013-03-05Clinical Trial Update: Assessment of the Cyberlink Control System for Use by the Amyotrophic Lateral Sclerosis (ALS) Patient
A clinical trial update indicating termination of the Cyberlink Control System study for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Ultrasound and Videofluoroscopy for Diagnosing Swallowing Disorders
A completed clinical trial evaluated ultrasound and videofluoroscopy as diagnostic tools for swallowing disorders in people with dysphagia a…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Brain Function in Primary Lateral Sclerosis
The update reports the completion of a clinical trial evaluating brain function in individuals with primary lateral sclerosis, a form of mot…