Monkeypox
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo [Phase 3]
Phase 3 trial of the JYNNEOS smallpox vaccine in adult healthcare personnel at risk for mpox in the Democratic Republic of the Congo has com…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production Cells [Phase 2]
Phase 2 comparability study evaluating the MVA-BN vaccine produced in different cell lines for monkeypox; the trial status is currently acti…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Phase 2 Randomized Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for Mpox [Phase 2]
This Phase 2 randomized multisite trial evaluating the MVA-BN mpox vaccine for monkeypox has completed, and results have been posted to info…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Clinical Study Investigating the Safety and Immune Responses After Immunization With Investigational Monkeypox Vaccines [Phase 1, Phase 2]
A combined Phase 1/2 trial of an investigational monkeypox vaccine by BioNTech completed, evaluating safety and immune responses.
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Ocular Complications of Mpox in the Democratic Republic Congo
A completed status update for NCT06579885 investigating ocular complications of mpox (monkeypox) in the Democratic Republic of Congo, sponso…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa [Phase 2]
Ongoing Phase 2 randomized trial evaluating the safety, reactogenicity, and immunogenicity of an mRNA-based Mpox vaccine candidate in Africa…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Tecovirimat in Non-hospitalized Patients With Monkeypox [Phase 3]
Tecovirimat is being studied in non-hospitalized monkeypox patients in a Phase 3 trial that has been suspended.
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Assessment of Safety Profile of MVA-BN Vaccine in the PALM-007 Study in DRC [Phase 4]
A Phase 4 PALM-007 study in the Democratic Republic of Congo assessed the safety of the MVA-BN vaccine for monkeypox; results have been post…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Tecovirimat for Treatment of Monkeypox Virus [Phase 2]
A Phase 2 clinical trial evaluating tecovirimat for the treatment of monkeypox has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Efficacy/Effectiveness, Safety, and Immunogenicity of LC16m8 Mpox Vaccine in Colombia [Phase 3]
This document provides an update on a Phase 3 trial in Colombia evaluating the efficacy, safety, and immunogenicity of the LC16m8 Mpox vacci…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Tecovirimat for Treatment of Monkeypox Virus - Study Extension Providing Standard of Care Only
A study extension of tecovirimat for monkeypox has completed, with the extension providing standard-of-care treatment only.
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV
A completed clinical trial evaluating morbidity, mortality, and risk factors of monkeypox (mpox) in HIV-negative high-risk individuals and p…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts
This completed prospective study followed high-risk contacts of mpox cases to evaluate biology, outcomes, transmission, and epidemiology.
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: European Trial Into Mpox Infection [Phase 4]
This update reports a Phase 4 European clinical trial investigating mpox infection (Monkeypox), currently in recruitment.
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure
Clinical trial update for the antiviral Tecovirimat (ST-246) used to treat exposure to orthopoxviruses, including smallpox and monkeypox; th…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine [Phase 2]
Phase 2 trial update evaluating immunogenicity of dose-reduction strategies for the MVA-BN Monkeypox vaccine; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: Study on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 Years [Phase 2, Phase 3]
Phase 2/3 trial evaluating immunogenicity, reactogenicity, and safety of the VACΔ6 vaccine in adults 18-60; study completed.
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CLINICAL_TRIALS trial_result · 2010-02-09Clinical Trial Update: Phase I Trial of an Investigational Small Pox Medication [Phase 1]
Phase I study of SIGA Technologies' investigational smallpox antiviral tecovirimat (ST-246) has completed and posted results.