Mixed Phenotype Acute Leukemia
📧 Sign up to get email alerts when something new happens for Mixed Phenotype Acute Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia [Phase 1]
A Phase 1 clinical trial sponsored by OHSU Knight Cancer Institute is evaluating a five-drug combination (venetoclax, dasatinib, prednisone,…
-
CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCT [Phase 1]
A Phase I clinical trial for patients with advanced hematologic malignancies undergoing allogeneic hematopoietic cell transplantation is cur…
-
CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases [Phase 2]
Phase 2 clinical trial evaluating a cord blood transplant using cyclophosphamide, fludarabine, and total-body irradiation in high-risk hemat…
-
CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: A Study of Revumenib and Mezigdomide in People With Leukemia [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/2 study of Revumenib and Mezigdomide for various forms of leukemia, currently recruiting.
-
CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Orca-T Expanded Access Program Study for Patients With Advanced Hematologic Malignancies
The Orca-T Expanded Access Program study for patients with advanced hematologic malignancies has a status update. The study is temporarily n…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL [Phase 1]
Phase 1 pharmacokinetic and safety study of MRX-2843 in adolescents and adults with relapsed/refractory acute myeloid leukemia, acute lympho…
-
CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in children, adolescent…
-
CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia [Phase 1, Phase 2]
Clinical trial update for 211At-BC8-B10 given before donor stem cell transplant in high-risk acute myeloid leukemia, acute lymphoblastic leu…
-
CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML [Phase 1]
A Phase I study of the selective nuclear export inhibitor KPT-330 (selinexor) in children with relapsed or refractory acute lymphoblastic le…
-
CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Feasibility and Safety of Donor-derived NK-cell Infusions for Leukemia Relapse Prophylaxis After Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial is evaluating the feasibility and safety of donor-derived natural killer cell infusions to prevent leukemia relapse…
-
CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant [Phase 1]
This clinical trial update describes a Phase 1 study evaluating HA-1 TCR T-cell immunotherapy for relapsed or refractory acute leukemia afte…
-
CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane [Phase 1]
Phase 1 clinical trial evaluating the highest dose of uproleselan in combination with fludarabine and cytarabine for relapsed or refractory …
-
CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating a four-drug combination (cladribine, idarubicin, cytarabine, and venetoclax) for acute myeloid leukemia, h…
-
CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse [Phase 1, Phase 2]
This clinical trial evaluates decitabine in combination with the FLAG-Ida chemotherapy regimen and total-body irradiation, followed by donor…
-
CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
This trial evaluates a targeted radiopharmaceutical (211At-BC8-B10) followed by an allogeneic donor stem cell transplant for relapsed or ref…
-
CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating naive T cell depletion to prevent chronic graft-versus-host disease in children and young adults receiving…
-
CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 3]
A Phase 3 randomized trial evaluating Orca-T in allogeneic stem cell transplantation for hematologic malignancies; results have been posted.
-
CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation [Phase 1]
A Phase 1 dose-escalation study of vorinostat after allogeneic hematopoietic cell transplantation is ongoing.
-
CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Study of Escalating Doses of INA03 Administered Intravenously as Single Agent in Adult Patients With Relapse/Refractory Acute Leukemia [EARLY_Phase 1]
An early-phase 1 study evaluated escalating intravenous doses of INA03 as a single agent in adults with relapsed or refractory acute leukemi…
-
CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL [Phase 2]
This Phase 2 trial evaluating blinatumomab for relapsed/refractory or MRD-positive CD19-positive mixed phenotype acute leukemia has complete…
-
CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: The Treatment of Newly Diagnosed CD19+Mixed Phenotype Acute Leukemia in Adults [EARLY_Phase 1]
An early-phase study at Ruijin Hospital is investigating treatment for newly diagnosed CD19+ Mixed Phenotype Acute Leukemia in adults. The t…
-
CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis [Phase 2, Phase 3]
A multi-agent trial in pediatric and young adult patients explores preventing graft-versus-host disease after transplantation using post-tra…
-
CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies [Phase 1]
Phase 1 clinical trial studying tagraxofusp in pediatric patients with CD123-expressing hematologic malignancies is currently recruiting, sp…
-
CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia [Phase 1]
A Phase 1 study evaluating the safety and potential efficacy of combining blinatumomab with nivolumab, with or without ipilimumab, in patien…
-
CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating a combination of post-transplant cyclophosphamide, abatacept, vedolizumab, and baricitinib to prevent graft…