Mixed Phenotype Acute Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in pediatric and young adult patie…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Pilot Imaging Study of Leukemia [Phase 1]
Phase 1 pilot imaging study in leukemia is currently recruiting. Conditions listed include acute lymphoblastic leukemia, acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study of revumenib in combination with chemotherapy for relapsed or refractory leukemia, with…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating venetoclax in combination with the CLAG-M chemotherapy regimen for acute myeloid leukemia and re…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
This entry describes a Phase 2 clinical trial evaluating Orca-T after reduced-intensity or nonmyeloablative conditioning in patients with ac…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms [Phase 1]
Phase 1 study evaluating FLAG-Ida chemotherapy plus pivekimab sunirine (IMGN632) for newly diagnosed adverse-risk acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) [Phase 1, Phase 2]
Phase I/II trial evaluating an engineered donor graft named Orca Q for pediatric hematopoietic cell transplantation is currently suspended. …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Subcutaneous Blinatumomab for Treatment of Adult Patients With CD19-Positive Mixed Phenotype Acute Leukemia (MPAL) [Phase 2]
A Phase 2 clinical trial is evaluating subcutaneous blinatumomab in adults with CD19-positive mixed phenotype acute leukemia (MPAL). The stu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia [Phase 3]
This entry provides a Phase 3 clinical trial protocol update for Interfant-21 in infants under 1 year with KMT2A-rearranged acute lymphoblas…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: HVA in the Treatment of Mixed-Phenotype Acute Leukemia(MPAL). [Phase 2]
The document reports an ongoing Phase 2 clinical trial evaluating HVA for newly diagnosed mixed-phenotype acute leukemia (MPAL), with enroll…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study [Phase 1, Phase 2]
PedAL BCU, LLC is conducting a pediatric screening trial to test bone marrow and blood methods in children with relapsed or hard-to-treat ac…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy [Phase 3]
A Phase 3 trial evaluating adding inotuzumab ozogamicin to post-induction chemotherapy for high-risk acute lymphoblastic leukemia, mixed phe…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 study to identify the highest dose of Revumenib (SNDX-5613) after hematopoietic stem cell transplant in children with acute lymphobl…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation [Phase 1, Phase 2]
A phase 1/2 trial evaluating Revumenib in relapsed/refractory leukemias including MLL/KMT2A rearrangements or NPM1 mutations; currently recr…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 trial evaluating HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplantation cyclophosphamide is act…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma [Phase 3]
Ongoing Phase 3 clinical trial evaluating levocarnitine to protect the liver from chemotherapy in children with acute lymphoblastic leukemia…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias [Phase 1]
A Phase I pediatric trial evaluating Hyper-CVAD in combination with venetoclax for relapsed or refractory acute leukemias of the lymphoid li…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting [Phase 2]
This clinical trial update describes a Phase 2 study of venetoclax plus azacitidine for acute myeloid leukemia in the post-transplant settin…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation [Phase 2]
Phase 2 trial update on enasidenib with azacitidine for recurrent or refractory acute myeloid leukemia with IDH2 mutation, currently recruit…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma [Phase 4]
Phase 4 clinical trial update from St. Jude focusing on identifying information needed to guide treatment induction in newly diagnosed acute…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) [Phase 2]
A Phase 2 pediatric trial is evaluating adding dasatinib or venetoclax to initial therapy to improve responses in newly diagnosed T-cell acu…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 3]
Phase 3 clinical trial evaluating imatinib mesylate in combination with chemotherapy for newly diagnosed Philadelphia chromosome-positive ac…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
This clinical trial update describes a Phase 1 study of Orca-Q for patients with hematologic malignancies undergoing allogeneic stem cell tr…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT [NA]
Clinical trial update indicates ongoing recruitment for a study evaluating CD45RA-depleted peripheral stem cell addback to prevent viral or …
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage [NA]
A clinical trial update notes a planned immune-targeted combination with chemotherapy for adult acute leukemia with ambiguous lineage (ALL/M…