Mixed Phenotype Acute Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-29Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
Phase 3 trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in pediatric and young adult patie…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms [Phase 1]
Phase 1 study evaluating FLAG-Ida chemotherapy plus pivekimab sunirine (IMGN632) for newly diagnosed adverse-risk acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT) [Phase 1, Phase 2]
Phase I/II trial evaluating an engineered donor graft named Orca Q for pediatric hematopoietic cell transplantation is currently suspended. …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Subcutaneous Blinatumomab for Treatment of Adult Patients With CD19-Positive Mixed Phenotype Acute Leukemia (MPAL) [Phase 2]
A Phase 2 clinical trial is evaluating subcutaneous blinatumomab in adults with CD19-positive mixed phenotype acute leukemia (MPAL). The stu…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 study to identify the highest dose of Revumenib (SNDX-5613) after hematopoietic stem cell transplant in children with acute lymphobl…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 trial evaluating HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplantation cyclophosphamide is act…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL) [Phase 2]
A Phase 2 pediatric trial is evaluating adding dasatinib or venetoclax to initial therapy to improve responses in newly diagnosed T-cell acu…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Orca-T Expanded Access Program Study for Patients With Advanced Hematologic Malignancies
The Orca-T Expanded Access Program study for patients with advanced hematologic malignancies has a status update. The study is temporarily n…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 3]
A Phase 3 randomized trial evaluating Orca-T in allogeneic stem cell transplantation for hematologic malignancies; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Study of Escalating Doses of INA03 Administered Intravenously as Single Agent in Adult Patients With Relapse/Refractory Acute Leukemia [EARLY_Phase 1]
An early-phase 1 study evaluated escalating intravenous doses of INA03 as a single agent in adults with relapsed or refractory acute leukemi…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL [Phase 2]
This Phase 2 trial evaluating blinatumomab for relapsed/refractory or MRD-positive CD19-positive mixed phenotype acute leukemia has complete…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies [Phase 1]
Phase 1 clinical trial studying tagraxofusp in pediatric patients with CD123-expressing hematologic malignancies is currently recruiting, sp…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Blinatumomab and Nivolumab With or Without Ipilimumab in Treating Patients With Poor-Risk Relapsed or Refractory CD19+ Precursor B-Lymphoblastic Leukemia [Phase 1]
A Phase 1 study evaluating the safety and potential efficacy of combining blinatumomab with nivolumab, with or without ipilimumab, in patien…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating a combination of post-transplant cyclophosphamide, abatacept, vedolizumab, and baricitinib to prevent graft…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia [Phase 1]
Phase 1 study evaluating revumenib in combination with chemotherapy for relapsed/refractory acute leukemias has completed.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Use of T-allo10 in Hematopoietic Stem Cell Transplantation (HSCT) for Blood Disorders [Phase 1]
Phase 1 trial update on T-allo10 for hematopoietic stem cell transplantation in various blood disorders; the NCT03198234 study sponsored by …
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: BeFluBu vs FluBuRux Conditioning in Haploidentical HCT [Phase 2]
Phase 2 clinical trial comparing BeFluBu vs FluBuRux conditioning regimens in haploidentical stem cell transplantation is currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe) [Phase 2]
This Phase 2 clinical trial update reports on conditioning with benadamustine, fludarabine, and busulfan (FluBuBe) for recipients of haploid…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients [Phase 2]
A Phase 2 study evaluating azacitidine, venetoclax, and flumatinib in newly diagnosed Ph-positive acute leukemia and CML-AP/BP; the trial ha…
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia [Phase 2]
Phase 2 trial evaluating a multi-drug regimen (clofarabine, idarubicin, cytarabine, vincristine, and dexamethasone) in newly diagnosed or re…
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement [Phase 2]
Phase 2 trial evaluating azacitidine with combination chemotherapy in infants with KMT2A-rearranged acute lymphoblastic leukemia and related…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 trial evaluating vincristine, doxorubicin, dexamethasone, and ixazomib in relapsed/refractory ALL, relapsed/refractory lymphoblastic…
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CLINICAL_TRIALS trial_result · 2019-10-11Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]
Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-25Clinical Trial Update: Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia [NA]
ClinicalTrials.gov update on a completed trial evaluating CPX-351 (liposomal cytarabine-daunorubicin) for untreated myelodysplastic syndrome…
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CLINICAL_TRIALS trial_result · 2015-12-10Clinical Trial Update: Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy
A completed clinical trial update assessing structural brain imaging and cognitive function in adult stem cell transplant recipients treated…