Mixed Phenotype Acute Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML [Phase 1]
A Phase I study of the selective nuclear export inhibitor KPT-330 (selinexor) in children with relapsed or refractory acute lymphoblastic le…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Feasibility and Safety of Donor-derived NK-cell Infusions for Leukemia Relapse Prophylaxis After Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial is evaluating the feasibility and safety of donor-derived natural killer cell infusions to prevent leukemia relapse…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant [Phase 1]
This clinical trial update describes a Phase 1 study evaluating HA-1 TCR T-cell immunotherapy for relapsed or refractory acute leukemia afte…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane [Phase 1]
Phase 1 clinical trial evaluating the highest dose of uproleselan in combination with fludarabine and cytarabine for relapsed or refractory …
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating a four-drug combination (cladribine, idarubicin, cytarabine, and venetoclax) for acute myeloid leukemia, h…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse [Phase 1, Phase 2]
This clinical trial evaluates decitabine in combination with the FLAG-Ida chemotherapy regimen and total-body irradiation, followed by donor…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
This trial evaluates a targeted radiopharmaceutical (211At-BC8-B10) followed by an allogeneic donor stem cell transplant for relapsed or ref…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating naive T cell depletion to prevent chronic graft-versus-host disease in children and young adults receiving…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation [Phase 1]
A Phase 1 dose-escalation study of vorinostat after allogeneic hematopoietic cell transplantation is ongoing.
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: The Treatment of Newly Diagnosed CD19+Mixed Phenotype Acute Leukemia in Adults [EARLY_Phase 1]
An early-phase study at Ruijin Hospital is investigating treatment for newly diagnosed CD19+ Mixed Phenotype Acute Leukemia in adults. The t…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis [Phase 2, Phase 3]
A multi-agent trial in pediatric and young adult patients explores preventing graft-versus-host disease after transplantation using post-tra…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Vitamin A and D Supplementation in Allogeneic HCT [Phase 2]
Phase 2 clinical trial in allogeneic hematopoietic cell transplantation is evaluating vitamin A and vitamin D supplementation, currently rec…
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CLINICAL_TRIALS research · 2021-06-02Clinical Trial Update: Humanized CD7 CAR T-cell Therapy for r/r CD7+ Acute Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating a humanized CD7 CAR T-cell therapy for relapsed/refractory CD7+ acute leukemia.
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CLINICAL_TRIALS research · 2018-07-26Clinical Trial Update: Management of Mixed-Phenotype Acute Leukemia in the East of France
A clinical trial update from Central Hospital in Nancy, France, regarding the management of mixed phenotype acute leukemia, with the current…