Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-like Episodes

• CLINICAL_TRIALS trial_result · 2026-03-25
  Clinical Trial Update: A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy [Phase 2, Phase 3]

  A Phase 2/3 study evaluating Vatiquinone for mitochondrial disease in participants with refractory epilepsy has been terminated, and results…

• CLINICAL_TRIALS research · 2026-01-29
  Clinical Trial Update: KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases [Phase 3]

  Khondrion's KHENERFIN study is a Phase 3 trial evaluating Sonlicromanol for mitochondrial diseases, currently recruiting.

• CLINICAL_TRIALS research · 2025-09-09
  Clinical Trial Update: A Study to Assess TTI-0102 vs Placebo in MELAS Patients [Phase 2]

  A Phase 2 study evaluating TTI-0102 versus placebo in MELAS patients is currently recruiting. The sponsor is Thiogenesis Therapeutics, Inc.

• CLINICAL_TRIALS trial_result · 2023-11-15
  Clinical Trial Update: Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS) [Phase 2]

  A Phase 2a trial of IW-6463 in adults with MELAS was terminated, and results were posted in November 2023.