Records containing: Metastatic Malignant Solid Neoplasm
This is the wording recorded or indexed by the source. An agency index term is not necessarily an authorised indication. Co-listed drug names are not linked to this term as a treatment relationship.
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CLINICAL_TRIALS study record update · 2026-04-13A Phase 1 Study of Pembrolizumab (MK-3475) in Combination With Recombinant Interleukin-12 in Patients With Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13A Phase I Study of DS-8201a in Combination With Olaparib in HER2-Expressing Malignancies
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CLINICAL_TRIALS study record update · 2026-04-13An Early Phase 1 Study of ABT-888 in Combination With Carboplatin and Paclitaxel in Patients With Hepatic or Renal Dysfunction and Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13A Phase I Study to Investigate the Safety of the Ubiquitin Activating Enzyme Inhibitor TAK-243 in Adult Solid Tumor and Lymphoma Patients
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CLINICAL_TRIALS study record update · 2026-04-13Genomically-Guided Treatment Trial in Brain Metastases
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CLINICAL_TRIALS study record update · 2026-04-13Pilot Study of Pidnarulex Pharmacodynamics in Patients With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13Phase 1/1B Study of DS-8201a in Combination With ATR Inhibition (AZD6738) in Advanced Solid Tumors With HER2 Expression (DASH Trial)
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CLINICAL_TRIALS study record update · 2026-04-13A Molecularly Driven Phase 1b Dose Escalation and Dose Expansion Study of the DNA-PK Inhibitor Peposertib (M3814) in Combination With the ATR Inhibitor M1774
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CLINICAL_TRIALS study record update · 2026-04-13Nilotinib and Paclitaxel in Patients With Prior Taxane-Treated Solid Tumors: A ComboMATCH Treatment Trial
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CLINICAL_TRIALS study record update · 2026-04-13A Phase 1 Study of BET Bromodomain Inhibitor ZEN003694 in Combination With the CDK4/6 Inhibitor Abemaciclib in Patients With NUT Carcinoma, Breast Cancer and Other Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13Phase 2 Study of Paclitaxel (NSC #673089) + Ipatasertib (NSC #781451) in Taxane-Refractory Participants With PTEN/AKT-Altered Advanced Non-Breast Solid Tumors: A ComboMATCH Treatment Trial
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CLINICAL_TRIALS study record update · 2026-04-13A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13Pilot Study of CBX-12 Pharmacodynamics in Patients With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13Phase I/Ib Trial Evaluating the Safety and Efficacy of BET Inhibitor, ZEN003694 With PD-1 Inhibitor, Nivolumab With or Without CTLA-4 Inhibitor, Ipilimumab in Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13Phase Ib Study of Copanlisib in Combination With Nivolumab or With Nivolumab and Ipilimumab
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CLINICAL_TRIALS study record update · 2026-04-13Optimizing Antibody-Drug Conjugate Therapy Through Molecular Analysis for Therapy Choice (ADC MATCH)
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CLINICAL_TRIALS study record update · 2026-04-13A Phase 1 Study of the Polymerase Theta (POLθ) Inhibitor Novobiocin in BRCA- Mutant and Other DNA Damage Repair-Deficient Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13Phase IIR Trial of Single Fraction Stereotactic Radiosurgery (SRS) Compared With Fractionated SRS (FSRS) for Intact Metastatic Brain Disease (FRACTIONATE)
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CLINICAL_TRIALS study record update · 2026-04-13A Phase 1 Study of ZEN003694 in Combination With Binimetinib in Solid Tumors With RAS Pathway Alterations and Triple Negative Breast Cancer
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CLINICAL_TRIALS study record update · 2026-04-13Phase I Clinical Trial of M6620 (VX-970, Berzosertib) in Combination With the Topoisomerase I Inhibitor Irinotecan in Patients With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13A Phase 1/2 Trial Evaluating the Combination of Temozolomide and the Ataxia Telangiectasia and Rad3-Related Inhibitor M1774
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CLINICAL_TRIALS study record update · 2026-04-13A Phase I/II Biomarker Driven Combination Trial of Copanlisib and Immune Checkpoint Inhibitors in Patients With Advanced Solid Tumors
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CLINICAL_TRIALS study record update · 2026-04-13A Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage Response
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CLINICAL_TRIALS study record update · 2026-04-03Phase III Trial of Single Fraction Stereotactic Radiosurgery (SRS) Versus Fractionated SRS (FSRS) for Intact Brain Metastases
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CLINICAL_TRIALS study record update · 2026-04-03A Basket Trial of Pembrolizumab in Patients With Advanced Solid Tumors and Genomic Instability